MRI: Acquisition of an Integrated Atomic Force and Fluorescence Microscope to Enhance Undergraduate Research at Wellesley College

MRI：购买集成原子力和荧光显微镜以加强韦尔斯利学院的本科生研究

• 批准号: 1528288
• 负责人: Megan Nunez
• 金额: $ 26.62万
• 依托单位: Wellesley College
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-08-15 至 2018-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1528288&HistoricalAwards=false
• 关键词: MRI; Acquisition; Integrated; Atomic; Force

An award is made to Wellesley College for the acquisition of an atomic force microscope integrated with a fluorescence microscope to enhance the educational and research experience of undergraduate microbiologists, biochemists, cell biologists, analytical chemists, and materials scientists. Wellesley College is an undergraduate college for women whose mission is "to provide an excellent liberal arts education for women who will make a difference in the world." As a liberal arts college, Wellesley focuses on educating a culturally diverse group of young women to be articulate, critical, and well-rounded thinkers and citizens. Roughly a third of students major in a scientific discipline, where they are involved in a rich, inquiry-based laboratory curriculum and independent research with faculty. Encouraged by their laboratory experience, many of them go on to careers in STEM fields. In the most recent NSF survey, Wellesley ranked first among all liberal arts colleges in generating female Ph.D.'s in math and science between 2008 and 2012 (199 Ph.D.s). In addition to supporting undergraduate education through research, this instrument will encourage collaboration between biological and physical scientists and between the Wellesley and Olin College communities, as they combine their disciplinary experience to investigate new questions or to take a new look at stubborn old questions. This research-grade integrated AFM-fluorescence microscope will enable students and faculty to sensitively measure very small and dynamic processes in several research areas. The Núñez lab (Chemistry), Klepac-Ceraj lab (Biological Sciences), and Huang lab (Olin College of Engineering) will explore the structure and dynamics of bacterial communities from diverse systems including predatory soil bacteria, oral biofilms, and green photosynthetic freshwater bacteria. Students in the Darling lab (Biological Sciences) will examine protein-protein interactions between cardiac cells. Young investigators in the Flynn lab (Chemistry) will determine the temporal dynamics of metal nanoparticle films at the nanometer scale. The Goss lab (Biological Sciences) will study exocytosis by the fission yeast S. pombe. Furthermore, undergraduate biology, chemistry, physics, and neuroscience students will use this instrument to discover the utility and limitations of fluorescence and scanning probe microscopies in their coursework, and they will measure nanoscale features and physical properties of polymers, optical components, and alloys in Olin College's materials science program.

授予韦尔斯利学院一个奖项，用于收购原子力显微镜与荧光显微镜集成，以提高本科微生物学家，生物化学家，细胞生物学家，分析化学家和材料科学家的教育和研究经验。 韦尔斯利学院是一所女子本科学院，其使命是“为将在世界上有所作为的女性提供优秀的文科教育。“作为一所文理学院，韦尔斯利专注于教育一群文化多样的年轻女性成为能言善辩、批判性强、全面发展的思想家和公民。大约三分之一的学生主修科学学科，在那里他们参与了丰富的，基于探究的实验室课程和与教师的独立研究。 在实验室经验的鼓舞下，他们中的许多人继续从事STEM领域的职业。在NSF最近的一次调查中，韦尔斯利在培养女博士方面在所有文科院校中排名第一。在2008年至2012年期间在数学和科学领域（199名博士）。 除了通过研究支持本科教育外，该工具还将鼓励生物和物理科学家之间以及韦尔斯利和奥林学院社区之间的合作，因为他们将联合收割机结合自己的学科经验来研究新问题或重新审视顽固的老问题。 这种研究级集成AFM荧光显微镜将使学生和教师能够灵敏地测量几个研究领域中非常小的动态过程。 Núñez实验室（化学），Klepac-Ceraj实验室（生物科学）和Huang实验室（奥林工程学院）将探索来自不同系统的细菌群落的结构和动态，包括捕食性土壤细菌，口腔生物膜和绿色光合淡水细菌。 Darling实验室（生物科学）的学生将研究心脏细胞之间的蛋白质-蛋白质相互作用。 Flynn实验室（化学）的年轻研究人员将在纳米尺度上确定金属纳米颗粒薄膜的时间动力学。戈斯实验室（生物科学）将研究分裂酵母S.粟酒 此外，本科生物学，化学，物理学和神经科学的学生将使用该仪器来发现荧光和扫描探针显微镜在他们的课程中的实用性和局限性，他们将测量聚合物，光学元件和合金的纳米级特征和物理特性在奥林学院的材料科学计划。