RUI: Characterizing the Sources, Fates, and Transformation Products of Conjugated, Free, and Halogenated Estrogens in a Sewage-Impacted River

RUI:描述受污水影响的河流中共轭雌激素、游离雌激素和卤化雌激素的来源、命运和转化产物

基本信息

  • 批准号:
    1606190
  • 负责人:
  • 金额:
    $ 32.52万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
    Standard Grant
  • 财政年份:
    2016
  • 资助国家:
    美国
  • 起止时间:
    2016-09-01 至 2020-08-31
  • 项目状态:
    已结题

项目摘要

1606190GriffithGlobally, wastewater can be a significant source of carbon, nutrients, and contaminants to surface waters. Endocrine disrupting chemicals such as steroidal estrogens, which have adverse effects on aquatic vertebrates at low concentrations, are among the compounds which can be in the wastewater. This study will be accomplished through a combination of laboratory, field, and modeling experiments, and will take advantage of previously optimized analytical techniques in the PIs laboratory.The overarching goal of this study is to improve the understanding of the fundamental processes that control wastewater derived sources and the environmental fate of estrogens and halogenated estrogens in aquatic systems. This study has the potential to transform our understanding of estrogen flux from typical wastewater treatment plants that utilize activated sludge secondary treatment and hypochlorite-based disinfection. The objectives of this project use a combination of laboratory, field, and modeling experiments to address: 1) halogenated estrogen formation and distribution in wastewater treatment plant effluent, 2) photolysis and biodegradation at environmentally relevant concentrations, and, 3) fate of halogenated estrogens in a sewage-impacted rivers. The data collected during this project will provide direct numerical inputs into simple mass balance and transport models that will be used to predict estrogen concentrations in the Willamette River, which is representative of many rivers that receive combined inputs from wastewater and storm water. This project will generate kinetic data and transformation product information for a range of estrogen structures that can be used to develop quantitative structure-activity relationships in the future, parameterize existing fate models, and determine the impact on the formation and fate of similar pharmaceuticals and organic contaminants in wastewater and natural waters. The PI and media experts at Mind Open Media will produce and distribute podcasts focused on the concepts and applications of wastewater treatment, and, the fate of chemicals in the environment. The PI will provide the research findings to state entities with a vested interest in wastewater treatment technologies and the health of river systems. Lastly, the project also funds undergraduate students to conduct research at a larger institution where they will be able to utilize the mass spectrometry facilities.
在全球范围内,废水可能是地表水中碳、营养物质和污染物的重要来源。内分泌干扰物,如类固醇雌激素,在低浓度时对水生脊椎动物有不利影响,是废水中可能存在的化合物之一。这项研究将通过实验室、现场和模拟实验相结合的方式完成,并将利用PIS实验室先前优化的分析技术。本研究的总体目标是提高对控制废水来源的基本过程以及水系统中雌激素和卤化雌激素的环境命运的理解。这项研究有可能改变我们对典型污水处理厂雌激素通量的理解,这些污水处理厂使用活性污泥二级处理和基于次氯酸盐的消毒。该项目的目标是结合实验室、现场和模拟实验来解决:1)污水处理厂出水中卤化雌激素的形成和分布,2)环境相关浓度下的光解和生物降解,以及3)受污水影响的河流中卤化雌激素的去向。在该项目期间收集的数据将为简单的质量平衡和运输模型提供直接的数字输入,这些模型将用于预测威拉米特河中的雌激素浓度,该河流代表了许多接受废水和雨水联合输入的河流。该项目将为一系列雌激素结构生成动力学数据和转化产品信息,可用于建立未来的定量结构-活性关系,对现有的命运模型进行参数化,并确定对废水和天然水中类似药物和有机污染物的形成和命运的影响。PI和Mind Open Media的媒体专家将制作和分发播客,重点关注废水处理的概念和应用,以及化学物质在环境中的命运。该研究所将向在废水处理技术和河流系统健康方面具有既得利益的国家实体提供研究结果。最后,该项目还资助本科生在一所更大的机构进行研究,在那里他们将能够利用质谱学设施。

项目成果

期刊论文数量(0)
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会议论文数量(0)
专利数量(0)

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David Griffith其他文献

Comparison of lipase and amylase for diagnosing post‐operative pancreatic fistulae
脂肪酶和淀粉酶诊断术后胰瘘的比较
  • DOI:
  • 发表时间:
    2018
  • 期刊:
  • 影响因子:
    1.7
  • 作者:
    David Griffith;T. Hanna;Kimberley Wong;A. Reece;S. Aroori;M. Bowles;D. Stell;C. Briggs
  • 通讯作者:
    C. Briggs
From city to countryside: recent changes in the structure and location of the meat- and fish-processing industries.
从城市到乡村:肉类和鱼类加工业的结构和布局的最新变化。
  • DOI:
  • 发表时间:
    1995
  • 期刊:
  • 影响因子:
    0
  • 作者:
    M. Broadway;D. Stull;David Griffith
  • 通讯作者:
    David Griffith
Fifty shades of grey: The role of endorectal ultrasound in rectal cancer staging
  • DOI:
    10.1016/j.ijsu.2013.06.229
  • 发表时间:
    2013-10-01
  • 期刊:
  • 影响因子:
  • 作者:
    Adam Smith;David Griffith;Jeremy Williamson;Rami Radwan;Mark Davies;Dean Harris;Martyn Evans;T.V. Chandrasekaran;U. Khot;John Beynon;B. Patel
  • 通讯作者:
    B. Patel
New immigrants in an old industry: Blue crab processing in Pamlico County, North Carolina.
老产业中的新移民:北卡罗来纳州帕姆利科县的蓝蟹加工。
  • DOI:
  • 发表时间:
    1995
  • 期刊:
  • 影响因子:
    0
  • 作者:
    David Griffith;D. Stull;M. Broadway
  • 通讯作者:
    M. Broadway
If it isn't something, it's something else...
如果不是某事,那就是别的事了……

David Griffith的其他文献

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{{ truncateString('David Griffith', 18)}}的其他基金

Rapid Response Research: The political and moral economies of recovery from Hurricanes Irma and Maria in Puerto Rico and the U.S. Virgin Islands.
快速反应研究:波多黎各和美属维尔京群岛飓风艾尔玛和玛丽亚恢复的政治和道德经济。
  • 批准号:
    1806303
  • 财政年份:
    2017
  • 资助金额:
    $ 32.52万
  • 项目类别:
    Standard Grant
RAPID: Theorizing Refugees and Local Labor Markets
RAPID:难民和当地劳动力市场的理论分析
  • 批准号:
    1643223
  • 财政年份:
    2016
  • 资助金额:
    $ 32.52万
  • 项目类别:
    Standard Grant
Managed Migration and the Value of Labor
管理移民和劳动力价值
  • 批准号:
    1157368
  • 财政年份:
    2012
  • 资助金额:
    $ 32.52万
  • 项目类别:
    Continuing Grant
Migration and Knowledge
移民与知识
  • 批准号:
    0722468
  • 财政年份:
    2007
  • 资助金额:
    $ 32.52万
  • 项目类别:
    Standard Grant
Relationships Among Multiple Livelihoods and Human, Social, and Cultural Capital
多种生计与人力、社会和文化资本之间的关系
  • 批准号:
    9706637
  • 财政年份:
    1997
  • 资助金额:
    $ 32.52万
  • 项目类别:
    Standard Grant
Immigrant Adjustment and Interethnic Relations in South Florida
南佛罗里达州的移民调整和种族间关系
  • 批准号:
    9211620
  • 财政年份:
    1992
  • 资助金额:
    $ 32.52万
  • 项目类别:
    Continuing Grant
Wage Labor and Economic Diversification in Small Scale Fishing
小规模渔业的工资劳动和经济多样化
  • 批准号:
    8718670
  • 财政年份:
    1988
  • 资助金额:
    $ 32.52万
  • 项目类别:
    Standard Grant
Adaptive Cephalic Imaging
自适应头部成像
  • 批准号:
    8210738
  • 财政年份:
    1983
  • 资助金额:
    $ 32.52万
  • 项目类别:
    Standard Grant

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