SusChEM: On the Role of Molecular Baskets in the Activation of Hydrocarbons and Stereoselective Recognition in Water

SusChEM:分子篮在水中碳氢化合物活化和立体选择性识别中的作用

基本信息

  • 批准号:
    1606404
  • 负责人:
  • 金额:
    $ 56.8万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
    Continuing Grant
  • 财政年份:
    2016
  • 资助国家:
    美国
  • 起止时间:
    2016-09-15 至 2021-08-31
  • 项目状态:
    已结题

项目摘要

With increasing rate of the population growth in the world, it is of prime interest to develop novel methods for the effective production of food, pharmaceuticals and advanced materials from sustainable resources and to reduce the reliance on petroleum-based chemicals. As the reserves of natural gas are large, Professor Badjic of Ohio State University explores the development of environmentally friendly and energy efficient ways to convert simple compounds that are abundant in natural gas into more complex structures with desired properties. In addition, his research group designs complex molecular "baskets" and investigates their potential use in chemical separation and as scavengers of toxic substances for cleaning the environment and recycling chemicals. This project enhances cultural and gender diversity by engaging underrepresented minorities and women in research. Outreach activities are designed to educate general public and high school students about the importance of sustainability for the progress of our society. There are two main goals for this project. The first one is to improve our understanding about the role of proximity and molecular encapsulation in the activation of carbon-hydrogen bonds of hydrocarbons. Specifically, Professor Badjic's research group studies the assembly of trivalent ligands and molecular baskets into ionic capsules that bind metal ions and examines their capacity to act as supramolecular catalysts in 'green' aqueous media for converting cheap and abundant hydrocarbons into valuable products. Another goal is to advance our knowledge about the kinetics and thermodynamics of stereoselective encapsulation and provide basic rules for predicting the recognition of chiral substances within the baskets and stereoselective activation of prochiral molecules. The resulting knowledge is expected to facilitate the design of chemical scavengers that can remove toxic substances and recycle useful chemicals from aqueous systems.
随着世界人口增长率的提高,开发新的方法以从可持续资源有效生产食品、药品和先进材料并减少对石油基化学品的依赖是最重要的。由于天然气的储量很大,俄亥俄州州立大学的Badjic教授探索开发环保和节能的方法,将天然气中丰富的简单化合物转化为具有所需性质的更复杂的结构。此外,他的研究小组设计了复杂的分子“篮子”,并研究了它们在化学分离中的潜在用途,以及作为有毒物质的清除剂来清洁环境和回收化学品。 该项目通过让代表性不足的少数民族和妇女参与研究,增强了文化和性别多样性。外联活动旨在教育公众和高中学生了解可持续发展对我们社会进步的重要性。这个项目有两个主要目标。 第一个是提高我们对邻近和分子封装在碳氢化合物的碳氢键活化中的作用的理解。 具体来说,Badjic教授的研究小组研究了三价配体和分子篮组装成离子胶囊,结合金属离子,并研究了它们在“绿色”水介质中作为超分子催化剂的能力,将廉价和丰富的碳氢化合物转化为有价值的产品。另一个目标是推进我们对立体选择性包封的动力学和热力学的知识,并提供基本的规则,用于预测篮子内的手性物质的识别和立体选择性激活的前手性分子。 由此产生的知识,预计将有助于设计的化学清除剂,可以去除有毒物质和回收有用的化学品从水系统。

项目成果

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Jovica Badjic其他文献

Jovica Badjic的其他文献

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{{ truncateString('Jovica Badjic', 18)}}的其他基金

Pillararene-Basket Conjugates, Deeper Cavity Baskets and Covalent Basket Cages for Allosteric Complexation of Toxicants
用于毒物变构络合的柱芳烃篮缀合物、深腔篮和共价篮笼
  • 批准号:
    2304883
  • 财政年份:
    2023
  • 资助金额:
    $ 56.8万
  • 项目类别:
    Standard Grant
CAS: Effective and Selective Sequestration of Functional Molecules with Baskets and Covalent Basket Cages
CAS:用篮子和共价篮笼有效选择性地封存功能分子
  • 批准号:
    2002781
  • 财政年份:
    2020
  • 资助金额:
    $ 56.8万
  • 项目类别:
    Standard Grant
Gated Molecular Encapsulation in Water
水中的门控分子封装
  • 批准号:
    1305179
  • 财政年份:
    2013
  • 资助金额:
    $ 56.8万
  • 项目类别:
    Standard Grant
Gated Molecular Encapsulation and Reactivity
门控分子封装和反应性
  • 批准号:
    1012146
  • 财政年份:
    2010
  • 资助金额:
    $ 56.8万
  • 项目类别:
    Standard Grant
Gated Molecular Baskets
门控分子篮
  • 批准号:
    0716355
  • 财政年份:
    2007
  • 资助金额:
    $ 56.8万
  • 项目类别:
    Continuing Grant

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