Seizure onset detection using tripolar Laplacian electroencephalography

使用三极拉普拉斯脑电图检测癫痫发作

• 批准号: 1622481
• 负责人: Oleksandr Makeyev
• 金额: $ 20万
• 依托单位: Dine College
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-09-15 至 2020-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1622481&HistoricalAwards=false
• 关键词: Seizure; onset; detection; using; tripolar

A goal of the Tribal Colleges and Universities Program (TCUP) is to increase the science, technology, engineering and mathematics (STEM) instructional and research capacities of specific institutions of higher education that serve the Nation's indigenous students. Expanding the research capacity at these institutions expands the opportunities for students to pursue challenging, rewarding careers in STEM fields, provides for research studies in areas that may be locally relevant, and encourages a faculty community to look beyond the traditional classroom for intellectual and professional growth. This project aligns directly with that goal, and moreover will increase the body of knowledge on the efficacy of novel devices that may improve the detection of seizure onset.Dine' College will analyze datasets in order to validate a novel tripolar Laplacian electroencephalogram (tEEG) based seizure onset detection methodology using automatically detected high-frequency oscillations (HFOs) with better sensitivity (correct detection rate), selectivity (false positive detections per hour), and detection delay compared to the recent results of others obtained on large scalp encephalogram (EEG) datasets will constitute a positive output. This project will contribute to advancing quality postsecondary student learning and development through the inter-disciplinary Mathematics for Engineering Applications (MEA) research laboratory to be established at Diné College led by the PI of and funded by this proposal. Four undergraduate research assistant positions will be created in the MEA lab providing Diné College students with valuable cutting edge research experience. Moreover, talks and presentations by the MEA lab members and invited speakers collaborating with the lab will help further involve students into mathematics and engineering disciplines.

部落学院和大学方案(TCUP)的一个目标是提高为本国土著学生服务的特定高等教育机构的科学、技术、工程和数学(STEM)教学和研究能力。扩大这些机构的研究能力扩大了学生在STEM领域追求具有挑战性的、有回报的职业的机会，提供了可能与当地相关的领域的研究性学习，并鼓励教师群体将目光投向传统课堂之外的智力和专业成长。Dine‘College将分析数据集，以验证基于自动检测高频振荡(HFO)的新型三极拉普拉斯脑电(TEEG)癫痫发作检测方法，该方法具有更好的灵敏度(正确检测率)、选择性(每小时假阳性检测)和检测延迟，与其他基于大型头皮脑电(EEG)数据获得的最新结果相比，将构成阳性输出。该项目将通过将在迪内学院建立的跨学科工程应用数学(MEA)研究实验室，促进高质量的中学后学生的学习和发展，该实验室将由国际数学研究所牵头，并由该建议提供资金。MEA实验室将设立四个本科生研究助理职位，为迪内学院的学生提供宝贵的尖端研究经验。此外，MEA实验室成员和与实验室合作的特邀演讲者的演讲和演讲将有助于学生进一步参与数学和工程学科。

项目成果

Validating the Comparison Framework for the Finite Dimensions Model of Concentric Ring Electrodes Using Human Electrocardiogram Data

• DOI: 10.3390/app9204279
• 发表时间: 2019-10-01
• 期刊: APPLIED SCIENCES-BASEL
• 影响因子: 2.7
• 作者: Makeyev, Oleksandr;Musngi, Mark;Garcia-Casado, Javier
• 通讯作者: Garcia-Casado, Javier

Evaluation of Bipolar, Tripolar, and Quadripolar Laplacian Estimates of Electrocardiogram via Concentric Ring Electrodes

• DOI: 10.3390/s19173780
• 发表时间: 2019-09-01
• 期刊: SENSORS
• 影响因子: 3.9
• 作者: Garcia-Casado, Javier;Ye-Lin, Yiyao;Makeyev, Oleksandr
• 通讯作者: Makeyev, Oleksandr

Improved Spatial Resolution of Electroencephalogram Using Tripolar Concentric Ring Electrode Sensors

• DOI: 10.1155/2020/6269394
• 发表时间: 2020-06-08
• 期刊: JOURNAL OF SENSORS
• 影响因子: 1.9
• 作者: Liu, Xiang;Makeyev, Oleksandr;Besio, Walter
• 通讯作者: Besio, Walter