Seizure onset detection using tripolar Laplacian electroencephalography

部落学院和大学计划（TCUP）的一个目标是提高为美国土著学生服务的特定高等教育机构的科学、技术、工程和数学（STEM）教学和研究能力。扩大这些机构的研究能力，可以扩大学生在STEM领域追求具有挑战性、回报丰厚的职业的机会，为当地相关领域的研究提供机会，并鼓励教师群体超越传统课堂，寻求智力和专业发展。该项目直接符合这一目标，而且将增加对可能提高癫痫发作检测的新型设备功效的知识体系。Dine' College将分析数据集，以验证一种新的基于三极拉普拉斯脑电图（tEEG）的癫痫发作检测方法，该方法使用自动检测高频振荡（hfo），具有更好的灵敏度（正确的检出率）、选择性（每小时假阳性检测）和检测延迟，与最近在大型头皮脑电图（EEG）数据集上获得的其他结果相比，将构成积极的输出。本计划将在迪纳尔学院成立一个跨学科的工程应用数学研究实验室，由该计划的首席研究员领导，并由该计划资助，以促进高等教育学生的学习和发展。MEA实验室将设立4个本科生研究助理职位，为din<s:1>学院学生提供宝贵的前沿研究经验。此外，MEA实验室成员的演讲和报告以及与实验室合作的受邀演讲者将有助于进一步让学生参与数学和工程学科。

A goal of the Tribal Colleges and Universities Program (TCUP) is to increase the science, technology, engineering and mathematics (STEM) instructional and research capacities of specific institutions of higher education that serve the Nation's indigenous students. Expanding the research capacity at these institutions expands the opportunities for students to pursue challenging, rewarding careers in STEM fields, provides for research studies in areas that may be locally relevant, and encourages a faculty community to look beyond the traditional classroom for intellectual and professional growth. This project aligns directly with that goal, and moreover will increase the body of knowledge on the efficacy of novel devices that may improve the detection of seizure onset.Dine' College will analyze datasets in order to validate a novel tripolar Laplacian electroencephalogram (tEEG) based seizure onset detection methodology using automatically detected high-frequency oscillations (HFOs) with better sensitivity (correct detection rate), selectivity (false positive detections per hour), and detection delay compared to the recent results of others obtained on large scalp encephalogram (EEG) datasets will constitute a positive output. This project will contribute to advancing quality postsecondary student learning and development through the inter-disciplinary Mathematics for Engineering Applications (MEA) research laboratory to be established at Diné College led by the PI of and funded by this proposal. Four undergraduate research assistant positions will be created in the MEA lab providing Diné College students with valuable cutting edge research experience. Moreover, talks and presentations by the MEA lab members and invited speakers collaborating with the lab will help further involve students into mathematics and engineering disciplines.