MRI: Acquisition of an X-ray Diffractometer at Purdue University

MRI：在普渡大学购买 X 射线衍射仪

• 批准号: 1625543
• 负责人: Tong Ren
• 金额: $ 21.85万
• 依托单位: Purdue University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-09-01 至 2019-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1625543&HistoricalAwards=false
• 关键词: MRI; Acquisition; ray; Diffractometer; Purdue

With this award from the Major Research Instrumentation Program (MRI) and support from the Chemistry Research Instrumentation Program (CRIF), Professor Tong Ren from Purdue University and colleagues Matthias Zeller and Suzanne Bart have acquired a single crystal X-ray diffractometer equipped with a molybdenum source. In general, an X-ray diffractometer allows accurate and precise measurements of the full three-dimensional structure of a molecule, including bond distances and angles, and provides accurate information about the spatial arrangement of a molecule relative to neighboring molecules. These studies impact a number of areas, including organic and inorganic chemistry, materials chemistry and biochemistry. This instrument is an integral part of teaching as well as research and research training of undergraduate and graduate students in chemistry and biochemistry at this institution that awards one of the largest number of PhD degrees in the country. The X-ray facility has a tradition of providing data collection and structure solution services for faculty and students from small colleges (PUIs) in the surrounding area. The diffractometer allows this courtesy to remain and be expanded. Finally, building on Purdue's ongoing efforts of making modern research instrumentation available at K-12 levels through the Purdue Science Express Program, the use of X-ray diffraction for K-12 educational purposes is being explored.The award is aimed at enhancing research and education at all levels, especially in areas such as (a) synthesizing conjugated metal acetylides, (b) studying organometallic chemistry of uranium complexes, (c) designing, preparing and investigating single-site catalysts used in green and sustainable chemistry transformations, (d) synthesizing bioactive molecules, (e) designing new HIV-1 protease inhibitors and (f) synthesizing highly reactive radical species.

在主要研究仪器项目（MRI）和化学研究仪器项目（CRIF）的支持下，普渡大学的任通教授及其同事Matthias Zeller和Suzanne Bart获得了一台配备钼源的单晶x射线衍射仪。一般来说，x射线衍射仪可以精确测量分子的完整三维结构，包括键距和角度，并提供有关分子相对于邻近分子的空间排列的准确信息。这些研究影响了许多领域，包括有机和无机化学、材料化学和生物化学。该仪器是该机构化学和生物化学本科生和研究生教学、研究和研究培训的一个组成部分，该机构是该国授予博士学位最多的机构之一。x射线设施有为周边地区小型学院（PUIs）的教师和学生提供数据收集和结构解决方案服务的传统。衍射仪使这种礼貌得以保留和扩展。最后，普渡大学正在努力通过普渡大学科学快车计划为K-12年级的学生提供现代研究仪器，并正在探索x射线衍射在K-12年级教育中的应用。该奖项旨在加强各级的研究和教育，特别是在以下领域：(a)合成共轭金属乙酰酯，(b)研究铀配合物的有机金属化学，(c)设计、制备和研究用于绿色和可持续化学转化的单位点催化剂，(d)合成生物活性分子，(e)设计新的HIV-1蛋白酶抑制剂和(f)合成高活性自由基。