MRI: Acquisition of a Field Emission Scanning Electron Microscope with STEM and EDS Capabilities for Interdisciplinary Research and Education at Towson University

MRI：陶森大学购买具有 STEM 和 EDS 功能的场发射扫描电子显微镜，用于跨学科研究和教育

• 批准号: 1626326
• 负责人: Vonnie Shields
• 金额: $ 53.05万
• 依托单位: Towson University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-10-01 至 2019-09-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1626326&HistoricalAwards=false
• 关键词: MRI; Acquisition; Field; Emission; Scanning

The scanning electron microscope requested in this proposal is an instrument capable of obtaining images of various materials and biological specimens with extremely high (nanoscale) resolution. The instrument also includes capability for analyzing the chemical composition of materials with high precision. The proposed instrument will be used to advance research in several areas of biological, chemical, geological and physical sciences, involving faculty and students across multiple departments in the Fisher College of Science and Mathematics at Towson University (TU). The ultrahigh resolution imaging and chemical analysis offered by the new scanning electron microscope is expected to enable break through discoveries that will impact the fundamental science in these diverse disciplines while also contributing to several technologies that are key to societal advancement and sustenance. Examples from the proposed research projects include enhancing our understanding of how and what chemosensory information is detected, analyzed, encoded, and responded to by the insect nervous system, exploring and manipulating the behavior of materials at extremely small size limits that underlie nanotechnology, harnessing the power of "meta materials" to achieve superconductivity at high temperatures with the potential of revolutionizing many technologies including power transmission and quantum computing, developing catalyst materials that are essential for achieving viable renewable and clean energy technologies, and understanding the mineral biosignature preservation in geological systems which is the key to finding life forms in extraterrestrial habitats. These projects will provide opportunities for active participation of undergraduate and master's students at TU and collaborating institutions, who will be trained and supervised by the faculty members on the use of this advanced instrument for interdisciplinary research. Student research will result in their authorship in journal publications and conference presentations. The research and professional careers of participating students is expected to benefit greatly from the hands-on experience and training on this advanced instrument. In addition, the instrument and the research it enables will also be employed to enhance class room and laboratory instructions in several undergraduate and master's level courses offered by the departments of Biological Sciences, Chemistry, and Physics, Astronomy and Geosciences. The K-12 partners will benefit through outreach activities, such as site visits and demonstrations, involving the instrument.This award from the Major Research Instrumentation program supports Towson University's (TU) acquisition of a state-of-the-art low vacuum 30keV Schottky field emission scanning electron microscope (FESEM) with capabilities for nanometer resolution in scanning transmission mode (S-TEM), in-situ e-beam patterning, and elemental analysis via energy dispersive X-ray spectroscopy (EDS). The instrument is crucial to meet the needs in ongoing and future research projects in inorganic, electronic, environmental, forensic, entomological and geobiological material. The FESEM will make a decisive impact in generating advanced scientific understanding, increased speed of research turn-around, and technological innovation by researchers at TU and its committed users from neighboring institutions, namely Loyola University of Maryland and Goucher College. Besides being a flexible tool catering to the ongoing inter-disciplinary research at TU, it will fill a void by serving as an in-house imaging, characterization, and structure fabrication instrument. The project addresses distinct research questions in individual and cross-disciplines, while sharing common characterization and fabrication needs. In short, these are: (1) image cuticular structures on the surface and within subsurface pores in biological samples using beam deceleration; (2) the ability to image with nanometer resolution zero-, two- and three-dimensional objects to understand optical property changes; (3) resolve with high resolution quantum sized nano clusters, ferro-fluids, metamaterial superconductors, perovskite catalysts, in S-TEM mode; (4) the ability to obtain high resolution lithographic patterning, and (5) elemental analysis using EDS. This suite of imaging, fabrication and chemical analysis capabilities within the instrument will allow researchers at TU, and its neighbors, to bolster ongoing research activities with student co-authors, while also propelling new learning outcomes in courses. It will equip students with an understanding of key technologies. This educational emphasis of primarily undergraduate institutions, like TU, affords unique opportunities for such training.

本提案所要求的扫描电子显微镜是一种能够以极高（纳米级）分辨率获得各种材料和生物标本图像的仪器。该仪器还具有高精度分析材料化学成分的能力。该仪器将用于推进生物、化学、地质和物理科学等多个领域的研究，涉及陶森大学费舍尔科学与数学学院多个系的教师和学生。新型扫描电子显微镜提供的超高分辨率成像和化学分析有望实现突破性发现，这些发现将影响这些不同学科的基础科学，同时也为社会进步和维持的关键技术做出贡献。提议的研究项目中的例子包括增强我们对昆虫神经系统如何以及哪些化学感觉信息被检测、分析、编码和响应的理解，探索和操纵纳米技术基础上极小尺寸材料的行为，利用“超材料”的力量在高温下实现超导性，具有革命性的许多技术潜力，包括电力传输和量子计算，开发催化剂材料，这对于实现可行的可再生能源和清洁能源技术至关重要，以及了解地质系统中矿物生物特征的保存，这是在地外栖息地寻找生命形式的关键。这些项目将为TU和合作机构的本科生和硕士生提供积极参与的机会，他们将在教师的培训和监督下使用这种先进的仪器进行跨学科研究。学生的研究将导致他们的作者在期刊出版物和会议报告。参与的学生的研究和职业生涯有望从这种先进仪器的实践经验和培训中受益匪浅。此外，该仪器及其研究成果还将用于生物科学系、化学系、物理系、天文学和地球科学系的一些本科和硕士课程的课堂和实验室教学。K-12合作伙伴将受益于涉及该乐器的外联活动，例如实地考察和示范。该奖项来自主要研究仪器项目，支持陶森大学（TU）购买最先进的低真空30keV肖特基场发射扫描电子显微镜（FESEM），该显微镜具有纳米分辨率的扫描传输模式（S-TEM）、原位电子束图像化和通过能量色散x射线光谱（EDS）进行元素分析的能力。该仪器对于满足无机、电子、环境、法医、昆虫学和地球生物学材料方面正在进行和未来研究项目的需要至关重要。FESEM将在产生先进的科学理解、提高研究周转速度和技术创新方面产生决定性影响，这些都是由TU的研究人员及其来自邻近机构（即马里兰洛约拉大学和古彻学院）的忠实用户进行的。除了作为一种灵活的工具来满足TU正在进行的跨学科研究之外，它还将填补内部成像、表征和结构制造仪器的空白。该项目解决了个人和跨学科的不同研究问题，同时分享了共同的表征和制造需求。简而言之，这些是：(1)利用光束减速成像生物样品表面和表面下孔隙中的角质层结构；(2)对零、二维和三维物体进行纳米分辨率成像，了解光学性质变化的能力；(3)在S-TEM模式下对高分辨率量子级纳米团簇、铁磁流体、超材料超导体、钙钛矿催化剂进行解析；(4)获得高分辨率光刻图案的能力；(5)使用EDS进行元素分析。仪器中的这套成像，制造和化学分析功能将使TU及其邻居的研究人员能够与学生共同作者一起支持正在进行的研究活动，同时也推动课程中的新学习成果。它将使学生了解关键技术。像TU这样的本科院校的教育重点为这种培训提供了独特的机会。

项目成果

Engaging Preservice Secondary Science Teachers in an NGSS-Based Energy Lesson: A Nanoscience Context

让职前中学科学教师参与基于 NGSS 的能源课程：纳米科学背景

• DOI: 10.1021/acs.jchemed.8b00169
• 发表时间: 2019
• 期刊: Journal of Chemical Education
• 影响因子: 3
• 作者: Menon, Deepika;Devadas, Mary Sajini
• 通讯作者: Devadas, Mary Sajini

Observation of plasmon-phonons in a metamaterial superconductor using inelastic neutron scattering

使用非弹性中子散射观察超材料超导体中的等离子体声子

• DOI: 10.1103/physrevb.100.024515
• 发表时间: 2019
• 期刊: Physical Review B
• 影响因子: 3.7
• 作者: Smolyaninova, Vera N.;Lynn, Jeffrey W.;Butch, Nicholas P.;Chen-Mayer, Heather;Prestigiacomo, Joseph C.;Osofsky, M. S.;Smolyaninov, Igor I.
• 通讯作者: Smolyaninov, Igor I.

Synthesis and Characterization of 2D-Graphene Oxide-Metal Hybrid Systems with Increased Solubility

溶解度增加的二维氧化石墨烯-金属杂化体系的合成和表征

• DOI: 10.1557/adv.2019.259
• 发表时间: 2019
• 期刊: MRS Advances
• 影响因子: 0.8
• 作者: Kelani, Hadi;Weatherbee, Shelby;Blama, Stephen;Devadas, Mary Sajini
• 通讯作者: Devadas, Mary Sajini

Signal detection limit of a portable Raman spectrometer for the SERS detection of gunshot residue

• DOI: 10.1557/mrc.2019.100
• 发表时间: 2019-09
• 期刊: MRS Communications
• 影响因子: 1.9
• 作者: Evan C. Thayer;W. Turner;Stephen Blama;M. S. Devadas;E. Hondrogiannis

Gold nanoparticles loaded with cullin-5 DNA increase sensitivity to 17-AAG in cullin-5 deficient breast cancer cells

• DOI: 10.1016/j.ijpharm.2019.04.022
• 发表时间: 2019-06-10
• 期刊: INTERNATIONAL JOURNAL OF PHARMACEUTICS
• 影响因子: 5.8
• 作者: Talamantez-Lyburn, Sarah;Brown, Pierce;Ehrlich, Elana S.
• 通讯作者: Ehrlich, Elana S.