Vascular Tissue Road-mapping Workshop & Micro-gravity Impact Roundtable

1642055-NeubertNSF已颁发奖项，支持参与者的差旅费和管理费用与"血管组织路线图研讨会微重力影响圆桌会议"正在举行的山景，加利福尼亚州，在美国宇航局艾姆斯研究中心，2016年8月20日。& 该提案建立在2015年NSF BME资助的研讨会上，该研讨会创建了一个路线图，确定了结束器官短缺的途径，里程碑和挑战。 本次研讨会的重点是确定的里程碑之一，“厚组织血管化”，这导致美国宇航局推出了“血管组织挑战赛”，并向第一个能够成功血管化的研究小组提供了50万美元的奖金。尽管人们对可能的技术了解很多，但对微重力可能带来的好处却知之甚少。 研讨会将为追求血管化目标的研究界提供一个机会，以更好地了解这条道路上的里程碑沿着，并了解更多关于可能的使能机会。研讨会将分为3个部分：1）血管组织路线图会议，2）血管组织挑战团队峰会，3）微重力环境对组织工程影响的圆桌会议。预期产出包括：1）一份关于血管化途径的路线图报告，以解决器官短缺问题，其中将包括识别和描述研究和资助团体共同感兴趣的具体里程碑和沿着挑战; 2）一份关于厚组织血管化最新技术水平的白色文件; 3）一份关于厚组织血管化研究小组可用资源和机会的白色文件和4）一份关于微重力对厚组织血管化影响的知识现状的白色文件。 主题演讲者和参与者将通过血管组织挑战团队名册，现有的新器官咨询委员会成员和厚组织血管化研究社区进行策划。 该研讨会预计将利用新的关系，为结束器官短缺的生物工程途径提供额外的奖项和挑战。 最终，这种崇拜将有助于推进为需要它们的患者提供再生的工程器官和组织的目标。

1642055 - NeubertNSF has made an award in support of participant travel costs and management costs associated with the "Vascular Tissue Road-mapping Workshops & Micro-gravity Impact Roundtable" being held in the Mountain View, CA, at the NASA Ames Research Center, August 20, 2016. The proposal builds upon a previous 2015 NSF BME funded workshop in which a Roadmap was created identifying pathways, milestones, and challenges toward ending the organ shortage. This workshop focuses on one of the identified milestones, "thick-tissue vascularization," which has led to NASA's launch of a "Vascular Tissue Challenge" with a $500,000 prize purse provided to the first research groups that can successfully vascularize 1 cm thick tissues with active parenchymal cells (liver, lung, heart, muscle, kidney cells.) Though much is known about possible techniques, very little is known about the possible enabling benefits of microgravity. The workshop will provide the research community pursuing this vascularization goal an opportunity to better understand the milestones along this pathway and learn more about possible enabling opportunities.The workshop will be conducted in 3 parts: 1) a Vascular Tissue Road-mapping session, 2) a Vascular Tissue Challenge Team Summit, and 3) a Roundtable on the micro-gravity environment's impact on tissue engineering. Outputs expected include: 1) A Road-mapping Report on the Vascularization Pathway towards solutions to the organ shortage that will include identification and descriptions of specific milestones and challenges along this pathway of mutual interest to the research and funding communities; 2) A White Paper on the current state of the art in thick-tissue vascularization; 3) A White Paper on available resources and opportunities for research groups pursuing thick-tissue vascularization and 4) A White Paper on the current state of knowledge about the impacts of micro-gravity on thick-tissue vascularization. Keynote speakers and participants will be curated through the Vascular Tissue Challenge team roster, existing New Organ Advisory Board members and the thick-tissue vascularization research community. The workshop is expected to leverage new relationships for additional prizes and challenges on the bioengineering pathways toward ending the organ shortage. Ultimately, the worship will help advance the goal of making regenerated, engineered organs and tissues available to patients who need them.