Novel Lanthanide Complexes and Polymeric Luminescent Chelates for Biomedical Imaging and Bioassay

用于生物医学成像和生物测定的新型稀土配合物和聚合物发光螯合物

• 批准号: DP0879996
• 负责人: A/Prof Evan Moore
• 金额: $ 20.85万
• 依托单位: The University of Melbourne
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2008
• 资助国家: 澳大利亚
• 起止时间: 2008-07-14 至 2011-07-13
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP0879996
• 关键词: Novel; Lanthanide; Complexes; Polymeric; Luminescent

The development of advanced materials and frontier technologies such as the luminescent chelates proposed here is essential for Australia's evolution as a competitive nation in fields such as biomedical imaging and clinical diagnostics. For example, the total expenditure on fluorescent reagents in 2004 exceeded US$1.5 billion, with an estimated 25% annual growth. With proven applications in diagnostic immunoassay and high throughput screening, the use of luminescent lanthanide complexes allows significant improvements over traditional fluorophores, facilitating miniaturisation and ultimately leading to reduced costs for the consumer.

先进材料和前沿技术的发展，如本文提出的发光螯合物，对于澳大利亚在生物医学成像和临床诊断等领域成为一个具有竞争力的国家至关重要。例如，2004年荧光试剂的总支出超过15亿美元，估计年增长率为25%。随着在诊断免疫测定和高通量筛选方面的成熟应用，发光镧系化合物的使用比传统的荧光团有了显著的改进，促进了小型化，并最终降低了消费者的成本。