CAREER: Carborane Cluster Architectures Featuring Multiple Metal-Boron Interactions

职业：具有多种金属-硼相互作用的碳硼烷簇结构在这个由化学部化学合成计划资助的项目中，南卡罗来纳州大学化学和生物化学系的Dmitry Peryshkov教授正在开发新的分子结构，在金属中心上实施独特的电子和几何环境。 反过来，这些结构预计将显着改变这些金属中心的化学反应性。一种不寻常的三维结构被称为碳硼烷，它由硼和碳原子簇组成，用于合成这些具有新化学键的金属络合物。该项目研究这些金属-硼键在有机分子活化和转化为有用产品中的作用。 Peryshkov博士还在制定一项外联倡议，促进南卡罗来纳州代表性不足的少数群体，包括历史上的黑人学院和大学的学生的研究生教育和科学研究。该计划为无机和有机金属化学的学生提供了教育和研究机会。在这个项目中，Peryshkov教授正在开发基于二十面体碳硼烷笼合成新型分子结构的方法。Peryshkov博士利用硼笼独特的三维几何结构和离域电子结构来获得硼簇表面金属中心的新型排列。碳硼烷、碳硼烷基和碳本烯键合模式之间的轻易相互转化在这些金属配合物的反应性中起着重要作用，并导致有机底物的协同活化。Peryshkov博士还在开发含有三元（B）（B）（M）金属杂环的新型（BB）-卡波姆络合物的合成方法，这些金属杂环是金属苯炔络合物的无机硼基类似物。这些碳炔的不寻常的电子结构导致与有机和无机亲电组分的反应性增强。在新的分子结构中的金属-硼相互作用的研究提供了一个基本的理解，为开发新的合成方法，功能化的硼簇和它们在催化转化中的利用。Peryshkov博士参与了旨在吸引和留住STEM学科有才华的学生的教育推广计划，目标是属于代表性不足的少数群体的本科生。

CAREER: Carborane Cluster Architectures Featuring Multiple Metal-Boron InteractionsIn this project funded by the Chemical Synthesis Program of the Chemistry Division, Professor Dmitry Peryshkov of the Department of Chemistry and Biochemistry at the University of South Carolina is developing novel molecular architectures that enforce unique electronic and geometric environments on metal centers. These architectures, in turn, are expected to significantly change the chemical reactivity of these metal centers. An unusual three-dimensional structure known as a carborane, which consists of a cluster of boron and carbon atoms, is utilized for the synthesis of these metal complexes with novel chemical bonds. This project studies the role of these metal-boron bonds in the activation and transformation of organic molecules into useful products. Dr. Peryshkov is also developing an outreach initiative, which promotes graduate-level education and scientific research among underrepresented minority groups in South Carolina, including students at Historically Black Colleges and Universities. This program integrates educational and research opportunities for students in inorganic and organometallic chemistry.In this project, Professor Peryshkov is developing methods to synthesize novel molecular architectures based on icosahedral carborane cages. Dr. Peryshkov utilizes the unique three-dimensional geometry and delocalized electronic structure of boron cages to access novel types of arrangements of metal centers on the surfaces of boron clusters. Facile interconversion between carborane, carboranyl, and carboryne bonding modes plays an important role in the reactivity of these metal complexes and leads to cooperative activation of organic substrates. Dr. Peryshkov is also developing synthetic methods for novel (BB)-carboryne complexes containing three-membered (B)(B)(M) metallacycles, which are inorganic boron-based analogs of metal benzyne complexes. The unusual electronic structure of these carborynes results in enhanced reactivity with organic and inorganic electrophilic components. Studies of metal-boron interactions in the novel molecular architectures provide a fundamental understanding for development of new synthetic approaches to functionalization of boron clusters and their utilization in catalytic transformations. Dr. Peryshkov is engaged in the educational outreach initiative aimed to attract and retain talented students in STEM disciplines targeting undergraduate students belonging to underrepresented minority groups.