VR-system for visuo-haptic stimulation during fMRI studies

用于 fMRI 研究期间视觉触觉刺激的 VR 系统

• 批准号: 227695754
• 负责人: Professorin Dr.-Ing. Angelika Peer
• 金额: --
• 依托单位: Max-Planck-Institut für biologische Kybernetik
• 依托单位国家: 德国
• 项目类别: Research Grants
• 财政年份: 2012
• 资助国家: 德国
• 起止时间: 2011-12-31 至 2017-12-31
• 项目状态: 已结题
• 来源: https://gepris.dfg.de/gepris/projekt/227695754?language=en
• 关键词: VR; system; visuo; haptic; stimulation

Reaching and grasping movements represent a fundamental interface for our interactions with the physical and social environment. Their dysfunction (as occurring in stroke patients) has serious consequences for all aspects of everyday life. Functional magnetic resonance imaging (fMRI) allows measuring the brain activity both in healthy subjects and in patient populations, thus substantially contributing to a better understanding of human brain function. However, up to now, the possibilities to investigate natural reach and grasp movements in the MR environment are severely limited, as suitable MR-compatible stimulation systems are rarely available and the movements result in severe artifacts in the fMRI measurements.The aim of the proposed project is (i) to realize a MR-compatible visuo-haptic stimulation system that allows investigating the brain activity during reach and grasp movements using fMRI and (ii) to optimize and adapt the fMRI acquisition and post-processing procedures.A final pilot study will validate the novel overall system and demonstrate its unique capabilities for studying natural (i.e., more complex and less restricted) movements.The VR system aims at the simultaneous presentation and control of visual and somatosensory information in spatial congruency. That is, the system will cover the two most important sensory channels for reach and grasp movements. It will be the first system allowing for the simultaneous testing of combined arm and finger movements in a MR environment. For the first time, brain processes that underlie natural reach-to-grasp movements can be characterized in detail. Our interdisciplinary proposal is characterized by the combination of innovative approaches towards advanced haptic displays and towards novel fMRI acquisition and analysis techniques. Both fields are tightly linked by the rigid validation of the developed novel methodology in a pilot study. This comprehensive approach ensures the usability of the novel overall system in many future studies to come, also in other brain imaging labs.

伸手和抓握动作代表了我们与物理和社会环境互动的基本界面。他们的功能障碍(发生在中风患者中)对日常生活的方方面面都有严重的后果。功能磁共振成像(FMRI)可以测量健康受试者和患者群体中的大脑活动，从而大大有助于更好地了解人类的大脑功能。然而，到目前为止，由于合适的MR兼容刺激系统很少可用，并且运动导致fMRI测量中的严重伪影，因此研究自然触觉和抓取运动的可能性严重受限。本项目的目标是(I)实现与MR兼容的视觉触觉刺激系统，该系统允许使用fMRI来研究触觉和抓取运动中的大脑活动，以及(Ii)优化和调整fMRI采集和后处理程序。最终的初步研究将验证新的整体系统，并展示其研究自然(即，更复杂和更少限制的运动。VR系统的目标是在空间一致性中同时呈现和控制视觉和体感信息。也就是说，该系统将覆盖伸展和抓取动作的两个最重要的感觉通道。这将是第一个允许在磁共振环境中同时测试手臂和手指组合运动的系统。第一次，作为自然伸手抓握动作基础的大脑过程可以被详细描述。我们的跨学科建议的特点是结合先进的触觉显示和新的功能磁共振成像采集和分析技术的创新方法。这两个领域通过在一项初步研究中对开发的新方法进行严格验证而紧密联系在一起。这种综合的方法确保了新的整体系统在未来的许多研究中的可用性，也包括在其他脑成像实验室中的可用性。

项目成果

Design of a new MR-compatible haptic interface with six actuated degrees of freedom

具有六个驱动自由度的新型 MR 兼容触觉界面的设计

• DOI: 10.1109/biorob.2014.6913792
• 发表时间: 2014
• 期刊: 5th IEEE RAS/EMBS International Conference on Biomedical Robotics and Biomechatronics
• 作者: M. A. Ergin;M. Kühne;A. Thielscher;A. Peer
• 通讯作者: A. Peer

An MR-Compatible Haptic Interface With Seven Degrees of Freedom

具有 7 个自由度的 MR 兼容触觉界面

• DOI: 10.1109/tmech.2018.2806440
• 发表时间: 2018
• 期刊: IEEE/ASME Transactions on Mechatronics
• 作者: M. Kühne;M. Eschelbach;A. Aghaeifar;L. von Pflugk;A. Thielscher;M. Himmelbach;K. Scheffler;P. van der Smagt;A. Peer
• 通讯作者: A. Peer

Comparison of prospective head motion correction with NMR field probes and an optical tracking system

• DOI: 10.1002/mrm.27343
• 发表时间: 2019-01-01
• 期刊: MAGNETIC RESONANCE IN MEDICINE
• 影响因子: 3.3
• 作者: Eschelbach, Martin;Aghaeifar, Ali;Scheffler, Klaus
• 通讯作者: Scheffler, Klaus

Second-order model for rotary traveling wave ultrasonic motors

• DOI: 10.1109/humanoids.2015.7363474
• 发表时间: 2015-12
• 期刊: 2015 IEEE-RAS 15th International Conference on Humanoid Robots (Humanoids)
• 作者: R. Garcia-Rochin;Markus Kuhne;R. Santiesteban-Cos;Guillermo Rubio-Astorga;A. Peer

Modeling and Two-Input Sliding Mode Control of Rotary Traveling Wave Ultrasonic Motors

• DOI: 10.1109/tie.2018.2798570
• 发表时间: 2018-09-01
• 期刊: IEEE TRANSACTIONS ON INDUSTRIAL ELECTRONICS
• 影响因子: 7.7
• 作者: Kuehne, Markus;Garcia Rochin, Roberto;Peer, Angelika
• 通讯作者: Peer, Angelika