Dissertation Research: A Phylogenomic and Specimen-based Bioinformatics Approach to Reconstruct Freshwater Mussel Evolution and Biogeography

论文研究：重建淡水贻贝进化和生物地理学的系统基因组学和基于样本的生物信息学方法

• 批准号: 1701901
• 负责人: Lawrence Page
• 金额: $ 1.95万
• 依托单位: University of Florida
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-06-01 至 2019-05-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1701901&HistoricalAwards=false
• 关键词: Dissertation; Research; Phylogenomic; Specimen; based

Freshwater mussels of the family Unionidae are ecologically and economically important, and the most species-rich family of freshwater bivalves worldwide. However, current understanding of tropical freshwater mussel relationships limits basic and applied research on the family, especially within mainland Southeast Asia (Indochina). This area is the global epicenter of unionid diversity and the most species-rich region for the group outside of North America. This research seeks to estimate the evolutionary history of freshwater mussels to examine species limits and geographical history of the group. The project will train one graduate student and two undergraduates in diverse systematics methods. Data from the project will be disseminated broadly via the MUSSEL Project database. Given the economic importance of the group, the resulting classification and phylogeny will provide a well-supported evolutionary framework for the future basic and applied research projects on the group.This research uses a phylogenomic and specimen-based bioinformatics approach to transform the current understanding of the evolutionary history and biogeography of freshwater mussels of Indochina. The diversity and distribution of the Indochinese freshwater mussel assemblage will be evaluated using hybrid enrichment of over two hundred exons and thousands of digitized museum records. This research aims to complete three primary objectives: 1) reconstruct the supraspecific relationships of the three major freshwater mussel radiations in Indochina; 2) revise the species-level diversity and geographic ranges of freshwater mussels in the region; 3) and analyze spatiotemporal patterns of freshwater mussel diversity.

蚌科（Unionidae）是世界上种类最丰富的淡水双壳类，具有重要的生态和经济价值。然而，目前对热带淡水贻贝关系的理解限制了对该家族的基础和应用研究，特别是在东南亚大陆（印度支那）。该地区是全球珠蚌多样性的中心，也是北美以外该群体物种最丰富的地区。这项研究旨在估计淡水贻贝的进化历史，以研究该群体的物种限制和地理历史。 该项目将培训一名研究生和两名本科生学习不同的系统学方法。 该项目的数据将通过MUSSEL项目数据库广泛传播。鉴于该群体的经济重要性，由此产生的分类和系统发育将提供一个良好的支持，为未来的基础和应用研究项目的group.This研究使用的生物基因组学和基于生物信息学的方法，以改变目前的理解的进化历史和淡水贻贝的印度支那。印度支那淡水贻贝组合的多样性和分布将使用超过200个外显子和数以千计的数字化博物馆记录的混合富集进行评估。本研究旨在完成三个主要目标：1）重建印度支那三个主要淡水贝类辐射区的超种关系; 2）修订该地区淡水贝类的物种水平多样性和地理范围; 3）分析淡水贝类多样性的时空格局。

项目成果

Molecular phylogeny and taxonomic revision of two enigmatic freshwater mussel genera (Bivalvia: Unionidae incertae sedis: Harmandia and Unionetta) reveals a diverse clade of Southeast Asian Parreysiinae

两个神秘的淡水贻贝属（双壳纲：Unionidae incertae sedis：Harmandia 和 Unionetta）的分子系统发育和分类学修订揭示了东南亚 Parreysiinae 的多样化分支

• DOI: 10.1093/mollus/eyy028
• 发表时间: 2018
• 期刊: Journal of Molluscan Studies
• 影响因子: 1.2
• 作者: Pfeiffer, John M;Graf, Daniel L;Cummings, Kevin S;Page, Lawrence M
• 通讯作者: Page, Lawrence M

Unioverse: A phylogenomic resource for reconstructing the evolution of freshwater mussels (Bivalvia, Unionoida)

• DOI: 10.1016/j.ympev.2019.02.016
• 发表时间: 2019-08-01
• 期刊: MOLECULAR PHYLOGENETICS AND EVOLUTION
• 影响因子: 4.1
• 作者: Pfeiffer, John M.;Breinholt, Jesse W.;Page, Larry M.
• 通讯作者: Page, Larry M.

A new genus and two new species of freshwater mussels (Unionidae) from western Indochina

印度支那西部淡水贻贝（贻贝科）一新属和二新种

• DOI: 10.1038/s41598-019-39365-1
• 发表时间: 2019
• 期刊: Scientific Reports
• 影响因子: 4.6
• 作者: Konopleva, Ekaterina S.;Pfeiffer, John M.;Vikhrev, Ilya V.;Kondakov, Alexander V.;Gofarov, Mikhail Yu.;Aksenova, Olga V.;Lunn, Zau;Chan, Nyein;Bolotov, Ivan N.
• 通讯作者: Bolotov, Ivan N.

Phylogeny of Mesoamerican freshwater mussels and a revised tribe‐level classification of the Ambleminae

中美洲淡水贻贝的系统发育和修订后的 Ambleminae 部落级别分类

• DOI: 10.1111/zsc.12322
• 发表时间: 2018
• 期刊: Zoologica Scripta
• 影响因子: 2.5
• 作者: Pfeiffer, John M.;Atkinson, Carla L.;Sharpe, Ashley E.;Capps, Krista A.;Emery, Kitty F.;Page, Lawrence M.
• 通讯作者: Page, Lawrence M.