Building an Inclusive Community of Biochemistry and Molecular Biology Educators to Develop Competencies for Facilitating Biomolecular Visual Literacy

建立一个包容性的生物化学和分子生物学教育者社区，以培养促进生物分子视觉素养的能力

• 批准号: 1712268
• 负责人: Daniel Dries
• 金额: $ 9.84万
• 依托单位: Juniata College
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-06-01 至 2019-05-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1712268&HistoricalAwards=false
• 关键词: Building; Inclusive; Community; Biochemistry; Molecular

Understanding the structure of biomolecules is a critical component of understanding their function; this information is important in fields such as personalized medicine, agricultural production, and biofuels development. Molecular visualization, or the ability to understand three-dimensionality from two-dimensional representation, is a useful element in this building this understanding, yet few instructors teach or assess the skills needed to interpret two-dimensional images. This project will develop strategies and approaches to help students gain these important skills. In particular, the project will build a community of biochemistry and molecular biology educators who will help develop a set of competencies defining specific tasks that students will be expected to perform to develop their molecular visualization skills. Specifically, during the one-year term of this project, a series of national and regional workshops will be organized to develop a community of educators who are dedicated to the task of producing reliable and valid molecular visualization concept inventories. This group will develop a framework of goals and objectives for understanding four fundamental themes in molecular visualization - Monomer Recognition, Topology and Connectivity, Alternate Renderings, and Molecular Interactions. The group will also develop and populate a website with the competencies arising from the workshops.This project will expand a framework established following an education symposium at the 2013 American Society for Biochemistry and Molecular Biology meeting to include competencies that will ultimately lead to constructing concept inventories in molecular visualization. This project will focus on four fundamental themes: Monomer Recognition, Topology and Connectivity, Alternate Renderings, and Molecular Interactions. Understanding these four themes will build a foundation that allows students to comprehend the structure-function relationship inherent in biomolecules. Regional workshops will bring together educators to identify and reach a consensus on competencies within these four themes. These competencies will be added to the molecular visualization framework housed at http://cbm.msoe.edu/crest/molviz/ for public use. This project has already begun to transform the way many biochemistry and molecular biology instructors use molecular representations in their classroom. For example, several instructors understand the need to assess their students' comprehension of the representations of a particular model before they used the model to draw higher level inferences (e.g. function). In articulating consensus-based learning goals and objectives and identifying competencies, this project will identify the foundations upon which concept inventories will be developed in future years. Importantly, this effort will be built around workshops that establish a community of practice for the explicit instruction of molecular visualization skills.

了解生物分子的结构是了解其功能的关键组成部分;这些信息在个性化医疗，农业生产和生物燃料开发等领域非常重要。 分子可视化，或从二维表示中理解三维的能力，是建立这种理解的有用元素，但很少有教师教授或评估解释二维图像所需的技能。 该项目将制定策略和方法，以帮助学生获得这些重要的技能。 特别是，该项目将建立一个生物化学和分子生物学教育工作者的社区，他们将帮助开发一套能力，定义学生将被期望执行的具体任务，以发展他们的分子可视化技能。 具体而言，在本项目的一年期内，将组织一系列国家和区域讲习班，以发展一个致力于制作可靠和有效的分子可视化概念清单的教育工作者社区。 该小组将制定一个目标和目标的框架，以理解分子可视化中的四个基本主题-分子识别，拓扑和连接，交替渲染和分子相互作用。 该小组还将开发和填充一个网站与讲习班产生的能力，该项目将扩大一个框架后，在2013年美国生物化学和分子生物学学会会议的教育研讨会，包括能力，最终导致构建概念库存在分子可视化。 这个项目将集中在四个基本主题：分子识别，拓扑和连接，交替渲染，和分子相互作用。 理解这四个主题将建立一个基础，让学生理解生物分子中固有的结构-功能关系。 区域讲习班将汇集教育工作者，以确定这四个主题范围内的能力并就此达成共识。 这些能力将被添加到http://cbm.msoe.edu/crest/molviz/上的分子可视化框架中，供公众使用。 这个项目已经开始改变许多生物化学和分子生物学教师在课堂上使用分子表征的方式。 例如，一些教师理解在他们使用模型来得出更高级别的推论（例如函数）之前，需要评估他们的学生对特定模型的表示的理解。 在阐明以共识为基础的学习目标和目的以及确定能力方面，本项目将确定今后几年编制概念清单的基础。 重要的是，这一努力将建立在讲习班，建立一个实践社区的分子可视化技能的明确指导。

项目成果

Meeting report: BioMolViz workshops for developing assessments of biomolecular visual literacy

会议报告：BioMolViz 开发生物分子视觉素养评估研讨会

• DOI: 10.1002/bmb.21440
• 发表时间: 2020
• 期刊: Biochemistry and Molecular Biology Education
• 影响因子: 1.4
• 作者: Procko, Kristen;Engelman, Shelly;Jakubowski, Henry;Beckham, Josh T.;Dean, Diane M.;Franzen, Margaret A.;Novak, Walter R. P.;Roberts, Rebecca;Roca, Alberto I.;Shor, Audrey C.
• 通讯作者: Shor, Audrey C.