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MRI: Acquisition of a fluorescence microscope for manipulating and imaging live cells

MRI：获取用于操作和成像活细胞的荧光显微镜

基本信息

批准号：
1727033
负责人：
Guy Hagen
金额：
$ 19.63万
依托单位：
University of Colorado at Colorado Springs
依托单位国家：
美国
项目类别：
Standard Grant
财政年份：
2017
资助国家：
美国
起止时间：
2017-09-01 至 2020-08-31
项目状态：
已结题

来源：
https://www.nsf.gov/awardsearch/showAward?AWD_ID=1727033&HistoricalAwards=false
关键词：
MRI Acquisition fluorescence microscope manipulating

项目摘要

An award is made to the University of Colorado, Colorado Springs to acquire a fluorescence microscope for manipulating and imaging live cells. The advanced microscope will be located in an open-access core facility and will support the long-term growth of research activities at the university. The new microscope will serve as a platform for basic research, for new innovations, and as a vital tool for research projects coming from investigators in multiple departments and across several disciplines. Acquisition of the microscope system will significantly support the research programs of the faculty members involved, and will enhance the hands-on training of many undergraduate and graduate students in state of the art technology through coursework and research.The award is aimed at enhancing interdisciplinary research and education at all levels, especially in areas such as (a) investigations of alternative approaches for super-resolution structured illumination microscopy, (b) using newly-developed genome editing technology and single molecule RNA-FISH methods to study the genetic basis of speciation in Drosophila, (c) studies of newly discovered cell-cell communication mechanisms in the immune system, (d) development of novel single-wall carbon nanotube probes for imaging live cells, and (e) studies of nanomaterial cytotoxicity.

科罗拉多州斯普林斯的科罗拉多大学获得了一项奖励，以获得用于操纵活细胞并为其成像的荧光显微镜。先进的显微镜将位于一个开放的核心设施中，并将支持该大学研究活动的长期增长。新的显微镜将作为基础研究、新创新的平台，并成为来自多个部门和几个学科的研究人员的研究项目的重要工具。获得显微镜系统将极大地支持相关教师的研究计划，并将通过课程和研究加强许多本科生和研究生在最新技术方面的动手培训。该奖项旨在加强各级跨学科研究和教育，特别是在以下领域：(A)研究超分辨率结构照明显微镜的替代方法，(B)使用新开发的基因组编辑技术和单分子RNA-FISH方法研究果蝇物种形成的遗传基础，(C)研究新发现的免疫系统中细胞与细胞之间的通讯机制，(D)开发用于成像活细胞的新型单壁碳纳米管探针，以及(E)研究纳米材料的细胞毒性。