MRI: Acquisition of a fluorescence-activated cell analyzer (FACS) to enhance undergraduate classroom and research experiences

MRI：购买荧光激活细胞分析仪（FACS）以增强本科生课堂和研究经验

• 批准号: 1920116
• 负责人: Melanie Gubbels Bupp
• 金额: $ 19.63万
• 依托单位: Randolph-Macon College
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-08-15 至 2023-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1920116&HistoricalAwards=false
• 关键词: MRI; Acquisition; fluorescence; activated; cell

An award is made to Randolph-Macon College to acquire a flow cytometer, an instrument capable of measuring up to 16 molecular properties of thousands of individual cells per second. Access to the flow cytometer will facilitate undergraduate research and training across disciplines and institutions. In particular, research projects supported by the instrument will enable the mentorship and training of over 25 undergraduate research students per year at Randolph-Macon College and Longwood University. An additional 50 students per year will benefit from the inclusion of the instrument in laboratory courses at Randolph-Macon College. Further, the acquisition of the cytometer will enhance outreach activities to Latina high school women enrolled in Randolph-Macon College's NSF-funded Pathways to Science Program and local middle school students. Overall, the addition of the flow cytometer to Randolph-Macon College will enhance the scientific training and literacy of undergraduate students, Latina high school students, local middle school students, and the general public.The flow cytometer will support research projects directed by seven faculty from two departments and three institutions, spanning a broad range of investigative topics. These topics include: a range of immunology studies, neural physiology, mammalian fertility, the evolution of brewer's yeast, and other topics. Overall these projects will enhance our understanding of the natural world and are likely to generate a significant degree of collaboration between the investigators and senior personnel, enhancing the already strong intellectual community at Randolph-Macon College and Longwood University. Results from projects enabled by the acquisition of the flow cytometer will be communicated in peer-reviewed publications and at regional and national scientific conferences.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

伦道夫-梅肯学院获得了流式细胞仪的奖励，这是一种每秒能够测量数千个细胞的多达16种分子特性的仪器。 使用流式细胞仪将促进跨学科和跨机构的本科生研究和培训。特别是，该工具支持的研究项目将使伦道夫梅肯学院和朗伍德大学每年超过25名本科研究生的导师和培训成为可能。 另外50名学生每年将受益于在伦道夫梅肯学院的实验室课程列入仪器。 此外，细胞计数器的购买将加强对参加伦道夫-梅肯学院NSF资助的科学之路项目的拉丁裔高中女生和当地中学生的外展活动。 总的来说，流式细胞仪的加入，伦道夫梅肯学院将提高本科生，拉丁高中学生，当地中学生和公众的科学培训和素养。流式细胞仪将支持由来自两个部门和三个机构的七名教师指导的研究项目，跨越广泛的调查主题。 这些主题包括：一系列免疫学研究，神经生理学，哺乳动物生育能力，啤酒酵母的进化，以及其他主题。 总的来说，这些项目将提高我们对自然世界的理解，并有可能产生调查人员和高级人员之间的合作，加强在伦道夫梅肯学院和朗伍德大学已经强大的知识界的显着程度。通过购买流式细胞仪而获得的项目结果将在同行评审的出版物以及区域和国家科学会议上进行交流。该奖项反映了NSF的法定使命，并通过使用基金会的知识价值和更广泛的影响审查标准进行评估，被认为值得支持。

项目成果

Malnutrition Disrupts T Cell Migration

营养不良会破坏 T 细胞的迁移

• DOI: 10.4049/jimmunol.208.supp.167.08
• 发表时间: 2022
• 期刊: The Journal of Immunology
• 作者: Dadzie, Kwesi A.;Foster, Takesha R;Mister, Abigail;Goulmamine, Syreen;Gibson, David;Adams, Olivia;Gubbels-Bupp, Melanie R
• 通讯作者: Gubbels-Bupp, Melanie R

The Effect of Malnutrition on T-cell Circadian Rhythms

营养不良对 T 细胞昼夜节律的影响

• DOI: 10.4049/jimmunol.208.supp.167.07
• 发表时间: 2022
• 期刊: The Journal of Immunology
• 作者: Foster, Takesha R.;Dadzie, Kwesi A;Adams, Olivia;Gubbels-Bupp, Melanie R
• 通讯作者: Gubbels-Bupp, Melanie R