MRI: Acquisition of High-Throughput Fluorescence Imaging System for Undergraduate Research and Teaching at Pace University

MRI：佩斯大学采购高通量荧光成像系统用于本科生研究和教学

• 批准号: 1919713
• 负责人: Aaron Steiner
• 金额: $ 37.23万
• 依托单位: Pace University New York Campus
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-09-01 至 2023-09-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1919713&HistoricalAwards=false
• 关键词: MRI; Acquisition; Throughput; Fluorescence; Imaging

An award is made to Pace University to acquire an automated high-resolution imaging system for screening large numbers of fluorescent zebrafish larvae and cancer cells. This automated imaging system will dramatically enhance scientific research at Pace University. Beyond being used by researchers at Pace University, the imaging system will also be integrated into the scientific training of undergraduate students enrolled in upper-division Biology and Chemistry courses. Students in these courses will gain hands-on research experiences and improve their quantitative and analytical skills as they work through the large datasets that they will collect. The use of the system in teaching laboratories will allow us to pursue inquiry-based projects within upper-level biology classes, exposing many more students to authentic scientific experimentation and discovery. The automated high-resolution fluorescence imaging system will be used to tackle a broad range of important questions from the fields of neuroscience, developmental biology, cancer biology, and biophysical chemistry. Furthermore, this imaging system will facilitate and promote interdepartmental research collaborations between the Biology and Chemistry departments, and engage undergraduates in publishable research. This imaging system will allow faculty and students to determine how various genes impact neural circuits, to identify key genes governing sensory organ development and regeneration, to examine cell proliferations, and to work on other topics. The results from the research obtained with this imaging system will be shared via scientific meetings and published in peer-reviewed journals.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

美国佩斯大学（Pace University）获得了一份合同，以获得一套自动高分辨率成像系统，用于筛选大量荧光斑马鱼幼虫和癌细胞。这种自动成像系统将极大地加强佩斯大学的科学研究。除了供佩斯大学的研究人员使用外，该成像系统还将被整合到高年级生物和化学课程的本科生的科学训练中。在这些课程中，学生将获得动手研究经验，并提高他们的定量和分析技能，因为他们将通过收集的大型数据集工作。在教学实验室中使用该系统将使我们能够在高级生物学课程中开展探究性项目，使更多的学生接触到真正的科学实验和发现。自动化高分辨率荧光成像系统将用于解决神经科学，发育生物学，癌症生物学和生物物理化学领域的广泛重要问题。此外，该成像系统将促进和促进生物和化学部门之间的跨部门研究合作，并吸引本科生进行可发表的研究。该成像系统将允许教师和学生确定各种基因如何影响神经回路，识别控制感觉器官发育和再生的关键基因，检查细胞增殖，并在其他主题上工作。使用该成像系统获得的研究结果将通过科学会议共享，并发表在同行评议的期刊上。该奖项反映了美国国家科学基金会的法定使命，并通过使用基金会的知识价值和更广泛的影响审查标准进行评估，被认为值得支持。