A History of Hormones and Blood Clots

激素和血栓的历史

• 批准号: 1755065
• 负责人: Jutta Schickore
• 金额: $ 1.58万
• 依托单位: Indiana University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-02-15 至 2019-01-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1755065&HistoricalAwards=false
• 关键词: History; Hormones; Blood; Clots

This historical project will study the role of blood clotting disorders in the development of the medicine for women. It will explore the role of the body in the development of medical theory and practice. The work will be of interest to medical advocates, citizens, doctors, and public health workers. The study will provide findings that may improve doctor-patient relationships, research methods, roles of bodies in research and development, and public health activism.The project will document the story of the development of the pill by looking at how the science was built upon the knowledge of what caused blood clots to form and how they moved throughout the body. The study will explore perceptions of risk and the asymmetry of risk by tracing the active agents in shaping pathological thought on venous blood clotting in the eighteenth and nineteenth centuries and ideas about hormonal contraception and its risks in the twentieth century. The project will use archival materials from pathologists, patients, and drug developers in order to trace the history of hormones and clotting risks. It will illustrate the many contributions of the patients and physicians involved in this research on blood clotting from the 18th- 20th centuries.

这一历史性项目将研究凝血障碍在妇女药物开发中的作用。它将探讨身体在医学理论和实践发展中的作用。这项工作将对医学倡导者、公民、医生和公共卫生工作者感兴趣。这项研究将提供可能改善医患关系、研究方法、研究和开发中身体的作用以及公共卫生行动主义的发现。该项目将通过观察科学是如何建立在什么导致血栓形成以及血栓如何在体内移动的知识基础上来记录避孕药的发展故事。这项研究将探讨风险的看法和风险的不对称性，通过追踪十八世纪和十九世纪形成静脉血液凝固病理思想的活性剂，以及二十世纪关于激素避孕及其风险的想法。该项目将使用来自病理学家，患者和药物开发人员的档案材料，以追踪激素和凝血风险的历史。 它将说明从18世纪到20世纪参与这项血液凝固研究的患者和医生的许多贡献。