Homotopy Methods for Computing Bifurcations and Multiple Solutions of Nonlinear Partial Differential Equations with Biological Applications
Homotopy Methods for Computing Bifurcations and Multiple Solutions of Nonlinear Partial Differential Equations with Biological Applications
批准号:
1818769
负责人:
Wenrui Hao
金额:
$10.0万
依托单位国家:
美国
项目类别:
Standard Grant
财政年份:
2018
资助国家:
美国
项目状态:
已结题
起止时间:
2018-08-01 至 2022-01-31
中文摘要
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英文摘要
Many mathematical models of natural phenomena, e.g., biology, physics and materials science, involve nonlinear systems of partial differential equations (PDEs). Traditional numerical methods focus on the unique time-marching solution and are very hard to capture these solution structures such as bifurcations, multiple steady states, and the structural stability. This project aims to address these challenges by developing efficient computational methods to explore bifurcations and multiple solutions of nonlinear PDEs.The aim of this project is to develop efficient numerical methods to study the bifurcations and multiple solutions of nonlinear systems of PDEs. Two novel numerical techniques are proposed to study nonlinear systems of PDEs. First, an adaptive homotopy tracking with bifurcation detection algorithm will be designed for computing bifurcation points and bifurcation solution branches based on adaptive tracking, endgame technique, and inflation process. Second, a homotopy method with optimal basis approximation will be developed to compute multiple solutions of nonlinear systems by optimizing the solution basis in order to minimize the size of the discretized polynomial system. Homotopy method will be employed to solve this bootstrapped discretized polynomial system. The project will also focus on demonstrating and verifying efficiency/reliability of these proposed numerical methods on the real biological problems which have attracted extensive mathematical studies since the models were proposed.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.
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Learn bifurcations of nonlinear parametric systems via equation-driven neural networks
通过方程驱动的神经网络学习非线性参数系统的分岔
DOI:
10.1063/5.0078306
发表时间:
2022
期刊:
Chaos: An Interdisciplinary Journal of Nonlinear Science
影响因子:
--
作者:
[Hao, Wenrui, Zheng, Chunyue]
通讯作者:
Zheng, Chunyue
convergence of a homotopy finite element method for computing steady states of Burgers' equation
用于计算 Burgers 方程稳态的同伦有限元方法的收敛性
DOI:
10.1051/m2an/2018046
发表时间:
2018
期刊:
ESAIM: Mathematical Modelling and Numerical Analysis
影响因子:
--
作者:
[Yang, Yong, Hao, Wenrui]
通讯作者:
Hao, Wenrui
DOI:
10.2140/camcos.2018.13.189
发表时间:
2018-01-01
期刊:
COMMUNICATIONS IN APPLIED MATHEMATICS AND COMPUTATIONAL SCIENCE
影响因子:
2.1
作者:
[Hao, Wenrui, Harlim, John]
通讯作者:
Harlim, John
A Stochastic Homotopy Tracking Algorithm for Parametric Systems of Nonlinear Equations
非线性方程组参数系统的随机同伦跟踪算法
DOI:
10.1007/s10915-021-01506-y
发表时间:
2021
期刊:
Journal of Scientific Computing
影响因子:
2.5
作者:
[Hao, Wenrui, Zheng, Chunyue]
通讯作者:
Zheng, Chunyue
Calibrations and validations of biological models with an application on the renal fibrosis
肾纤维化生物学模型的校准和验证
DOI:
10.1002/cnm.3329
发表时间:
2020
期刊:
International Journal for Numerical Methods in Biomedical Engineering
影响因子:
2.1
作者:
[Karagiannis, Georgios, Hao, Wenrui, Lin, Guang]
通讯作者:
Lin, Guang
共 11 条
Collaborative Research: Personalized Modeling of Alzheimer’s Disease
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批准号:2052685
-
项目类别:Standard Grant
-
资助金额:$22.0万
-
财政年份:2021
-
负责人:Wenrui Hao
-
依托单位:
国内基金
海外基金
Computational Methods for Analyzing Toponome Data
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批准号:60601030
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项目类别:青年科学基金项目
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资助金额:17.0万元
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批准年份:2006
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负责人:Axel Mosig
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依托单位: