Phase II IUCRC at Kansas State University: Center for Wheat Genetic Resources (WGRC)

堪萨斯州立大学 IUCRC 第二阶段：小麦遗传资源中心 (WGRC)

• 批准号: 1822162
• 负责人: Eduard Akhunov
• 金额: $ 50万
• 依托单位: Kansas State University
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-07-15 至 2024-06-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1822162&HistoricalAwards=false
• 关键词: Phase; II; IUCRC; Kansas; State

Wheat is immensely valued as a staple crop and commodity throughout the world, accounting for over 20% of all protein and calories worldwide while contributing an estimated $30 billion boost to the US economy. Wheat production faces the combined challenges of increasingly variable and unfavorable climates, including new disease and insect pest pressures. In this context, new climate resilient varieties with a broadened genetic base must be developed. As a raw ingredient to the success of new wheat varieties, novel genetic diversity from wild relatives is needed to improve performance and resilience to stress. The Wheat Genetics Resource Center (WGRC) Industry-University Cooperative Research Center (IUCRC) at Kansas State University has the primary focus of effectively and efficiently mining these genetic resources and accelerating delivery of improved diverse germplasm to industry partners with cross-cutting training of the next generation of wheat industry scientists. The delivery of novel genetic resources and high-caliber scientists to industry partners is the ground work for future advancements and success in the wheat industry. The resulting improvement of yield potential and nutritional quality in wheat contributes toward resilience of the agriculture sector and the accessibility of affordable and nutritious wheat-based foods to society.The complex wheat genome, more than five times larger than the human genome, and the narrow genetic base of bread wheat, present formable challenges in breeding and to address problems facing the wheat industry. Managing wheat genetic diversity to improve crop performance and training of new scientists are major functions of the WGRC IUCRC-and are critical success factors for the wheat research enterprise. The center is advancing full genetic characterization and curation of thousands of accessions of wheat wild relatives across all genomes and ploidy levels while leveraging this information to develop improved germplasm for delivery to industry partners. With targeted understanding of the genetic diversity, accessing and delivering novel alleles in improved germplasm through allele mining can be greatly expedited. Technical innovations for efficiently accessing and transferring genes and chromosomes from wild relatives will allow rapid transfer of useful traits to elite germplasm through targeted chromosome engineering, increased recombination, marker assisted breeding and genomic prediction. Through collaborative industry testing networks, the center delivers improved germplasm including chromosome introgression stocks and diverse populations with 1) abiotic stress tolerance, 2) resistance to disease and insects, 3) yield potential and stability and 4) end-use nutrition and grain quality.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

小麦作为一种主食作物和商品在世界各地都很有价值，占全球蛋白质和卡路里总量的20%以上，同时为美国经济贡献了约300亿美元。小麦生产面临着日益多变和不利气候的综合挑战，包括新的疾病和虫害压力。在这种情况下，必须开发具有更广泛遗传基础的适应气候变化的新品种。作为小麦新品种成功的一个重要因素，来自野生近缘种的新的遗传多样性是提高小麦生产性能和抗逆性的必要条件。堪萨斯州立大学的小麦遗传资源中心（WGRC）产学研合作研究中心（IUCRC）的主要重点是有效和高效地挖掘这些遗传资源，并通过对下一代小麦产业科学家的交叉培训，加速向产业合作伙伴提供改良的多样化种质。向行业合作伙伴提供新的遗传资源和高素质的科学家是小麦行业未来进步和成功的基础工作。由此带来的小麦产量潜力和营养质量的提高有助于提高农业部门的抵御力，并有助于社会获得负担得起的营养小麦食品。复杂的小麦基因组比人类基因组大五倍多，而面包小麦的遗传基础狭窄，这给育种和解决小麦行业面临的问题带来了挑战。管理小麦遗传多样性以提高作物性能和培养新科学家是WGRC - iucrc的主要职能，也是小麦研究事业成功的关键因素。该中心正在推进对所有基因组和倍性水平的数千种小麦野生近缘种的全面遗传表征和管理，同时利用这些信息开发改进的种质资源，交付给行业合作伙伴。有针对性地了解遗传多样性，可以通过等位基因挖掘来获取和传递改良种质中的新等位基因。通过有针对性的染色体工程、增加重组、标记辅助育种和基因组预测，有效获取和转移野生近缘基因和染色体的技术创新将使有用性状快速转移到优质种质。通过协作的行业测试网络，该中心提供改良的种质资源，包括染色体渐渗库存和具有1)非生物胁迫耐受性，2)抗病虫害，3)产量潜力和稳定性以及4)最终用途营养和粮食质量的多样化种群。该奖项反映了美国国家科学基金会的法定使命，并通过使用基金会的知识价值和更广泛的影响审查标准进行评估，被认为值得支持。

项目成果

Resistance gene cloning from a wild crop relative by sequence capture and association genetics

• DOI: 10.1038/s41587-018-0007-9
• 发表时间: 2019-02-01
• 期刊: NATURE BIOTECHNOLOGY
• 影响因子: 46.9
• 作者: Arora, Sanu;Steuernagel, Burkhard;Wulff, Brande B. H.
• 通讯作者: Wulff, Brande B. H.

Extrachromosomal DNA‐mediated glyphosate resistance in Italian ryegrass

意大利黑麦草染色体外 DNA 介导的草甘膦抗性

• DOI: 10.1002/ps.7626
• 发表时间: 2023
• 期刊: Pest Management Science
• 影响因子: 4.1
• 作者: Koo, Dal‐Hoe;Ju, Yoonha;Putta, Karthik;Sathishraj, Rajendran;Burgos, Nilda;Jugulam, Mithila;Friebe, Bernd;Gill, Bikram S.
• 通讯作者: Gill, Bikram S.

Homoeologous Recombination: A Novel and Efficient System for Broadening the Genetic Variability in Wheat

• DOI: 10.3390/agronomy10081059
• 发表时间: 2020-08-01
• 期刊: AGRONOMY-BASEL
• 影响因子: 3.7
• 作者: Koo, Dal-Hoe;Friebe, Bernd;Gill, Bikram S.
• 通讯作者: Gill, Bikram S.

Development and Molecular Cytogenetic Characterization of Cold-Hardy Perennial Wheatgrass Adapted to Northeastern China

• DOI: 10.3389/fpls.2020.00582
• 发表时间: 2020-05
• 期刊: Frontiers in Plant Science
• 影响因子: 5.6
• 作者: Wei Yan;Xin Jin;Bo Jiang;X. Qi;Ya-xin Chen;Xinling Li;Xiaoqiang Liu;Yongkang Ren;Lei Cui-Lei

Introgression of a Novel Ug99-Effective Stem Rust Resistance Gene into Wheat and Development of Dasypyrum villosum Chromosome-Specific Markers via Genotyping-by-Sequencing (GBS)

• DOI: 10.1094/pdis-05-18-0831-re
• 发表时间: 2019-06-01
• 期刊: PLANT DISEASE
• 影响因子: 4.5
• 作者: Ando, Kaori;Krishnan, Vandhana;Pumphrey, Michael O.
• 通讯作者: Pumphrey, Michael O.