MRI: Acquisition of a Confocal Microscope for Student-Faculty Research and Research Training

MRI：购买共焦显微镜用于师生研究和研究培训

• 批准号: 1828041
• 负责人: Marta Laskowski
• 金额: $ 57.62万
• 依托单位: Oberlin College
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-10-01 至 2021-09-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1828041&HistoricalAwards=false
• 关键词: MRI; Acquisition; Confocal; Microscope; Student

An award is made to Oberlin College to support the acquisition of a confocal microscope for use by faculty from Oberlin's Biology, Chemistry & Biochemistry, and Neuroscience Departments and by faculty at other institutions in the region. The confocal system will advance undergraduate training through mentored research and expansion of course-based research. The increased ease of use and robustness of the requested confocal will greatly expand Oberlin's ability to support student use in individually mentored research and in curricular offerings, while the higher scan speed, greater sensitivity, and addition of environmental control will enhance data collection. Science education at Oberlin will therefore be enhanced by the improved activity and productivity of individual faculty research programs. Access to up-to-date instrumentation is essential to prepare students for careers in scientific research, and Oberlin College faculty will incorporate the new confocal system into four upper-level investigative laboratory courses as well as mentored research where broadening participation of under-represented student groups is particularly emphasized. Modern confocal microscopy systems improve the types and quality of data that researchers can obtain and expand the range of research questions faculty can undertake. Oberlin researchers will use the system to gain deeper insight into developmental and biochemical processes through analysis of the mechanisms leading to organ initiation and spacing in plants, regulation of a proton mediated cell-cell signaling event in C. elegans, embryo formation in marsupials, immune responses to intracellular bacterial pathogens, and a range of neuroscience topics. Data and analyses from these studies will be published in peer-reviewed scientific journals, presented at scientific meetings, and used in both educational and public outreach activities.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

一个奖项是作出奥伯林学院，以支持收购共聚焦显微镜使用的教师从奥伯林的生物学，化学，生物化学和神经科学部门和教师在该地区的其他机构。共聚焦系统将通过指导研究和扩展基于课程的研究来推进本科生培训。所要求的共聚焦的易用性和鲁棒性的增加将大大扩展奥伯林的能力，以支持学生在单独指导的研究和课程中使用，而更高的扫描速度，更高的灵敏度，并增加环境控制将增强数据收集。 因此，奥伯林的科学教育将通过提高教师个人研究项目的活动和生产力来加强。获得最新的仪器是必不可少的准备学生的职业生涯在科学研究，和奥伯林学院教师将新的共聚焦系统纳入四个上层调查实验室课程，以及指导的研究，扩大代表性不足的学生群体的参与是特别强调。现代共聚焦显微镜系统提高了研究人员可以获得的数据的类型和质量，并扩大了教师可以承担的研究问题的范围。奥伯林的研究人员将利用该系统，通过分析导致植物器官启动和间隔的机制，C.线虫，有袋动物的胚胎形成，对细胞内细菌病原体的免疫反应，以及一系列神经科学主题。这些研究的数据和分析将发表在同行评审的科学期刊上，在科学会议上发表，并用于教育和公共宣传活动。该奖项反映了NSF的法定使命，并被认为值得通过使用基金会的知识价值和更广泛的影响审查标准进行评估来支持。