I-Corps: An Individualized 3D Printed Silicone Bottle Nipple

I-Corps：个性化 3D 打印硅胶奶嘴

• 批准号: 1838368
• 负责人: Rasim Guldiken
• 金额: $ 5万
• 依托单位: University of South Florida
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-07-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1838368&HistoricalAwards=false
• 关键词: Corps; Individualized; 3D; Printed; Silicone

The broader impact/commercial potential of this I-Corps project is improved health and economic impact as a result of a 3D printing technology, combined with fluid dynamic modeling, that has the potential to prolong breastfeeding. An individualized, 3D printed silicone bottle nipple, that closely mimics a mother's breast, creates continuity between bottle and breast, reducing the primary barrier to breastfeeding, nipple confusion. Prolonged breastfeeding and skin to skin contact enables breast milk to continually act in establishing immunity, enabling protective neurological development, and genetic optimization through microbiome establishment. The core technology of this project has a commercialization potential to solve issues mothers face every day and the global societal impact of the innovation could be substantial. It is projected that increasing rates of breastfeeding could save the lives of more than 820,000 children under age five, annually, prevent 20,000 breast cancer deaths, while saving $300 billion annually in health care costs worldwide. This I-Corps project aims to evaluate the commercialization potential of a baby bottle nipple concept which replicates a mother's nipple in terms of shape and texture while matching the flow rate to that of the maternal flow rate. One of the intellectual merits of the innovation is its individualized 3D printed silicone bottle nipple which addresses nipple confusion related to shape based on a 3D survey of a mother's nipples. The 3D scanning technology allows mothers to use an application to scan their breasts to be able to select which 3D printed mold fits their breasts the best, leading to seamless bottle to breast continuity. The innovation also appropriately addresses nipple confusion related to flow rate in its design. The team conducted fluid dynamics analyses to determine the flow rate through the printed nipple that matches the flow rate from a small data set from preterm mothers. The core technology has the potential to allow better continuity between the breast and bottle, help enable mothers to overcome the barriers they face so they can continue breastfeeding for the recommended minimum of 2 years.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

这个i-Corps项目的更广泛的影响/商业潜力是，3D打印技术与流体动力学建模相结合，有可能延长母乳喂养，从而改善健康和经济影响。个性化的3D打印硅胶奶瓶奶嘴，模仿母亲的乳房，在奶瓶和乳房之间创造了连续性，减少了母乳喂养的主要障碍，乳头混乱。长时间的母乳喂养和皮肤接触使母乳能够继续发挥作用，建立免疫力，保护神经发育，并通过建立微生物组进行遗传优化。该项目的核心技术具有商业化潜力，可以解决母亲们每天面临的问题，这项创新的全球社会影响可能是巨大的。据预测，提高母乳喂养率每年可以挽救82万多名五岁以下儿童的生命，防止2万人死于乳腺癌，同时每年在全球范围内节省3000亿美元的医疗费用。这个i-Corps项目旨在评估婴儿奶瓶乳头概念的商业化潜力，这种概念在形状和质地方面复制了母亲的乳头，同时使流速与母亲的流速相匹配。这项创新的智力价值之一是其个性化的3D打印硅胶奶瓶乳头，它基于对母亲乳头的3D调查，解决了与乳头形状有关的乳头困惑。3D扫描技术允许母亲使用应用程序扫描她们的乳房，以便能够选择最适合她们乳房的3D打印模具，从而实现从奶瓶到乳房的无缝连接。这一创新还适当地解决了设计中与流量有关的乳头混乱问题。研究小组进行了流体动力学分析，以确定通过打印的乳头的流速与来自早产母亲的小数据集的流速相匹配。这项核心技术有可能使母乳和奶瓶之间更好地保持连续性，帮助母亲克服她们面临的障碍，使她们能够在建议的至少两年内继续母乳喂养。该奖项反映了NSF的法定使命，并通过使用基金会的智力优势和更广泛的影响审查标准进行评估，被认为值得支持。