Conference: 2018 Enzymes, Coenzymes and Metabolic Pathways GRS: How Enzymes Work: From Mechanism and Function to Therapeutic Applications; July 21-22, 2018; Waterville Valley, NH

本项目将组织一次关于酶、辅酶和代谢途径的戈登研究研讨会（GRS）。本次研讨会将在戈登酶、辅酶和代谢途径定期研究会议之前举行。“酶”GRS是早期职业研究人员的关键会议，专注于剖析生化反应的分子机制，并为在非正式环境中分享想法和建立网络提供了一个中心会议场所。本次研讨会的长期目标是促进研究生和博士后之间的互动和合作，专注于研究酶在生命基础生物过程中的作用。GRS创建了一个由13名演讲者组成的项目（其中12名从研究生和博士后提交的摘要中选择），1名确定的研究者作为主题演讲者。这些讲座将描述当前在理解酶机制方面的进展，以及研究它们的跨学科方法。此外，GRS将举办职业指导小组（6位来自不同背景的领导者），让学生和博士后作为酶研究领域的科学家接触不同的职业选择，帮助他们在不同的道路之间做出选择，如果他们还没有这样做，或者与他们已经选择的特定职业的小组成员建立联系。代表性不足的群体成员、女学生和博士后将被特别邀请参加。本次研讨会由分子和细胞生物科学部分子生物物理组部分资助。该奖项反映了美国国家科学基金会的法定使命，并通过使用基金会的知识价值和更广泛的影响审查标准进行评估，被认为值得支持。

This project will organize a Gordon Research Seminar (GRS) on Enzymes, Coenzymes, and Metabolic Pathways. This seminar will precede the regular Gordon Research Conference on Enzymes, Coenzymes, and Metabolic Pathways. The "Enzymes" GRS is the pivotal conference for early-career researchers focused on dissecting the molecular mechanisms of biochemical reactions and provides a central meeting place for sharing ideas and networking in an informal setting. The long-term goals of this seminar are to foster interactions and collaborations within the graduate-student and postdoc community focused on studying the roles of enzymes in the biological processes that are fundamental for life. The GRS has created a program of 13 Speakers (12 chosen from abstracts submitted by graduate students and postdocs, and 1 established investigator as a Keynote Speaker. These talks will describe current advances in understanding enzyme mechanisms, interdisciplinary methods to study them. Additionally, the GRS will hold a Career Mentorship Panel (6 leaders from diverse backgrounds), to expose the students and postdocs to different career options as scientists in the field of enzyme research, to help them decide between different paths if they have not done so yet, or to network with the panelists in the specific career they have already chosen. Members of underrepresented groups and female students and postdocs will specifically be invited to participate. This seminar is partially funded by the Molecular Biophysics Cluster of the Molecular and cellular Biosciences Division.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.