Center for the Advancement of Wearable Technologies (CAWT): Engineered (Bio)Interfaces, Energy Harvesting/Storage and Data Analytics for Health and Diagnostic Monitoring

可穿戴技术促进中心 (CAWT)：用于健康和诊断监测的工程（生物）接口、能量收集/存储和数据分析

• 批准号: 1849243
• 负责人: Arturo Hernandez-Maldonado
• 金额: $ 1710万
• 依托单位: University of Puerto Rico
• 依托单位国家: 美国
• 项目类别: Cooperative Agreement
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-07-01 至 2025-06-30
• 项目状态: 未结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1849243&HistoricalAwards=false
• 关键词: Center; Advancement; Wearable; Technologies; CAWT

This project aims to build significant research capacity in Puerto Rico (PR) in the wearable technology field by forming the Center for the Advancement of Wearable Technologies (CAWT). The center will build on the research capacity developed by prior nanoscience research activities funded by the NSF Established Program to Stimulate Competitive Research (EPSCoR) and managed by the PR EPSCoR office. CAWT is structured around three goals: 1) advance the fundamental and applied science of biosensors, portable power and storage, and data analytics; 2) provide an engaged and diverse workforce for the nation's wearable technology sector; and 3) stimulate economic development together with PR's medical device industry. PR EPSCoR will utilize a rich network of academic, industry, and government partnerships to access state-of-the-art equipment, research opportunities for trainees and build a robust innovation ecosystem. The project will also leverage established infrastructure in PR for education, outreach, workforce development activities to make significant strides towards developing a diverse, next-generation STEM workforce that is well-aligned with the science priorities of the jurisdiction. PR EPSCoR will build a Center for the Advancement of Wearable Technologies (CAWT) to leverage the jurisdiction's research strengths in nanotechnology towards advancing the wearable technology field. Providing easy access to new types of wearable devices that sense and monitor health conditions and provide consistent, reproducible, and personalized medical information is essential for continued growth within the wearable technology sector. Wearable devices face three fundamental research and development challenges: 1) ensuring that functional components made of materials that are fully compatible with end users; 2) generating adequate and lasting power; and 3) updating data analytics to utilize and manage steady streams of data generated wearable devices. The CAWT motivates its research agenda by these challenges and is thus organized into three Interdisciplinary Research Groups (IRGs). IRG1 focuses on the design of optical and electrochemical sensors, microfluidic platforms, and characterization studies of materials components that come in direct contact with biological materials. IRG2 aims to harness existing low-level energy sources to drive low-power wearable devices and investigate new multicomponent battery materials. IRG3 aims to develop big data tools to address materials design problems and support the experimental design of projects within IRG1 and IRG2. The CAWT seeks to build a research agenda that creates novel and sustainable research lines while also building up a workforce that can address needs within the local medical device industry. This project will realize PR EPSCoR's goal of building research capacity, advancing scientific discovery in wearable technology, developing a well-trained and diverse scientific workforce, and promoting economic development throughout the region.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

该项目旨在通过成立可穿戴技术进步中心（CAWT），在波多黎各（PR）建立可穿戴技术领域的重要研究能力。该中心将建立在先前纳米科学研究活动所开发的研究能力的基础上，这些活动由NSF建立的刺激竞争性研究计划（EPSCoR）资助，并由PR EPSCoR办公室管理。CAWT围绕三个目标构建：1)推进生物传感器，便携式电源和存储以及数据分析的基础和应用科学；2)为国家的可穿戴技术部门提供敬业和多样化的劳动力；3)与PR的医疗器械产业一起带动经济发展。PR EPSCoR将利用丰富的学术、行业和政府合作伙伴网络，为学员提供最先进的设备和研究机会，并建立一个强大的创新生态系统。该项目还将利用现有的公共关系基础设施进行教育、推广和劳动力发展活动，在培养多元化的下一代STEM劳动力方面取得重大进展，这与该司法管辖区的科学优先事项非常一致。PR EPSCoR将建立一个可穿戴技术发展中心（CAWT），以利用该司法管辖区在纳米技术方面的研究优势，推动可穿戴技术领域的发展。提供易于访问的新型可穿戴设备，以感知和监测健康状况，并提供一致、可重复和个性化的医疗信息，对于可穿戴技术领域的持续增长至关重要。可穿戴设备面临着三个根本性的研发挑战：1)确保由与最终用户完全兼容的材料制成的功能部件；2)产生充足、持久的电力；3)更新数据分析，利用和管理可穿戴设备生成的稳定数据流。CAWT通过这些挑战来推动其研究议程，因此被组织成三个跨学科研究小组（irg）。IRG1专注于光学和电化学传感器的设计，微流体平台，以及与生物材料直接接触的材料组件的表征研究。IRG2的目标是利用现有的低能量源来驱动低功耗可穿戴设备，并研究新的多组分电池材料。IRG3旨在开发大数据工具来解决材料设计问题，并支持IRG1和IRG2项目的实验设计。CAWT寻求建立一个研究议程，创建新颖和可持续的研究线，同时也建立一支能够满足当地医疗设备行业需求的劳动力队伍。该项目将实现PR EPSCoR的目标，即建立研究能力，推进可穿戴技术的科学发现，培养一支训练有素的多元化科学队伍，并促进整个地区的经济发展。该奖项反映了美国国家科学基金会的法定使命，并通过使用基金会的知识价值和更广泛的影响审查标准进行评估，被认为值得支持。

项目成果

Monitoring decellularization via absorbance spectroscopy during the derivation of extracellular matrix scaffolds.

• DOI: 10.1088/1748-605x/ac361f
• 发表时间: 2021-11-26
• 期刊: Biomedical materials (Bristol, England)

CuB monolayer: a novel 2D anti-van’t Hoff/Le Bel nanostructure with planar hyper-coordinate boron/copper and superconductivity

• DOI: 10.20517/jmi.2022.10
• 发表时间: 2022
• 期刊: Journal of Materials Informatics
• 作者: Kaixiong Tu;Jinxing Gu;Linguo Lu;Shijun Yuan;Long Zhou;Zhongfang Chen

Planar Hypercoordinate Motifs in Two-Dimensional Materials

二维材料中的平面超坐标基序

• DOI: 10.1021/acs.accounts.0c00025
• 发表时间: 2020
• 期刊: Accounts of Chemical Research
• 影响因子: 18.3
• 作者: Wang Yu;Li Yafei;Chen Zhongfang
• 通讯作者: Chen Zhongfang

Fabrication of paper-based microfluidic devices using a 3D printer and a commercially-available wax filament

使用 3D 打印机和市售蜡丝制造纸基微流体装置

• DOI: 10.1016/j.talo.2022.100142
• 发表时间: 2022
• 期刊: Talanta Open
• 作者: Espinosa, Antonio;Diaz, Joannes;Vazquez, Edgar;Acosta, Lina;Santiago, Arianna;Cunci, Lisandro
• 通讯作者: Cunci, Lisandro

MX Anti-MXenes from Non-van der Waals Bulks for Electrochemical Applications: The Merit of Metallicity and Active Basal Plane

• DOI: 10.1021/acsnano.0c08429
• 发表时间: 2021-03-18
• 期刊: ACS NANO
• 影响因子: 17.1
• 作者: Gu, Jinxing;Zhao, Ziyuan;Chen, Zhongfang
• 通讯作者: Chen, Zhongfang