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REU Site: Mechanobiology at VCU

REU 网站：VCU 机械生物学

基本信息

批准号：
1852116
负责人：
Rebecca Heise
金额：
$ 33.19万
依托单位：
Virginia Commonwealth University
依托单位国家：
美国
项目类别：
Standard Grant
财政年份：
2019
资助国家：
美国
起止时间：
2019-06-01 至 2023-05-31
项目状态：
已结题

来源：
https://www.nsf.gov/awardsearch/showAward?AWD_ID=1852116&HistoricalAwards=false
关键词：
REU Site Mechanobiology VCU

项目摘要

This REU site in Mechanobiology at the Virginia Commonwealth University (VCU) College of Engineering will annually engage a diverse cohort of undergraduate students and faculty members in biomedical engineering research projects in areas related to mechanobiology. Mechanobiology is an emerging field at the interface of biology and engineering that focuses on how physical forces and changes in the mechanical properties of cells and tissues contribute to development, physiology, and disease. The field of mechanobiology is a rapidly expanding research area that requires a unique set of interdisciplinary skills. The individual projects in this REU program will be focused on gaining interdisciplinary skills related to cell mechanics, mechanobiology in drug delivery, pulmonary mechanics, and orthopedic regenerative medicine. Furthermore, trainees will learn the basic scientific method, statistics skills, research ethics, and the workings of collaborative biomedical research laboratories. This 10 week summer REU site has 3 goals for the participants. The first goal is to increase participation in mechanobiology research. The second goal is to provide opportunities to enhance scientific literacy and communication at the interface of engineering and life sciences. The third goal is to prepare trainees for graduate study or research careers in mechanobiology or related fields. The students will be equipped with cutting-edge research skills in mechanobiology including microfabricated post arrays, mechanotransduction pathway analysis, FRET-based force sensing, cell-material interactions, and mechanically enabled drug delivery. Student participants will also participate in a local outreach activity that enhances engineering knowledge of K-12 students and teachers. At weekly meetings, students will learn about research techniques, participate in journal clubs, and hear talks from experts in mechanobiology. At the end of each summer, students will participate in a research symposium and draft abstracts to present their work at a national engineering meeting.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

这个REU网站在机械生物学在工程的弗吉尼亚联邦大学（VCU）学院将每年从事本科生和教师在生物医学工程研究项目在与机械生物学领域的多元化队列。机械生物学是生物学和工程学的一个新兴领域，专注于细胞和组织的物理力和机械特性的变化如何促进发育，生理学和疾病。机械生物学领域是一个快速发展的研究领域，需要一套独特的跨学科技能。在这个REU计划的个人项目将侧重于获得相关的细胞力学，药物输送机械生物学，肺力学和骨科再生医学的跨学科技能。此外，学员将学习基本的科学方法，统计技能，研究道德和合作生物医学研究实验室的工作。这个为期10周的夏季REU网站有3个目标的参与者。第一个目标是增加对机械生物学研究的参与。第二个目标是提供机会，提高工程和生命科学的科学素养和沟通。第三个目标是为机械生物学或相关领域的研究生学习或研究职业做好准备。学生将具备机械生物学方面的尖端研究技能，包括微制造后阵列，机械转导通路分析，基于FRET的力传感，细胞-材料相互作用和机械药物输送。学生参与者还将参加当地的推广活动，提高K-12学生和教师的工程知识。在每周的会议上，学生将学习研究技术，参加期刊俱乐部，并听取机械生物学专家的演讲。在每年夏季结束时，学生将参加一个研究研讨会和草案摘要，介绍他们的工作在一个国家工程会议。这个奖项反映了NSF的法定使命，并已被认为是值得通过评估使用基金会的智力价值和更广泛的影响审查标准的支持。