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REU Site: Engineered Materials for Tissue Engineering and Drug Delivery

REU 网站：用于组织工程和药物输送的工程材料

基本信息

批准号：
1852609
负责人：
Adam Engler
金额：
$ 35.16万
依托单位：
University of California-San Diego
依托单位国家：
美国
项目类别：
Standard Grant
财政年份：
2019
资助国家：
美国
起止时间：
2019-04-01 至 2023-03-31
项目状态：
已结题

来源：
https://www.nsf.gov/awardsearch/showAward?AWD_ID=1852609&HistoricalAwards=false
关键词：
REU Site Engineered Materials Tissue

项目摘要

This Research Experiences for Undergraduates (REU) Site focuses on the expanding research opportunities in biomaterials as the community discovers new applications of and regulation by biomaterials. Hosted by the Jacobs School of Engineering at the University of California-San Diego, this site will provide research opportunities and professional development for a diverse cohort of talented undergraduates from traditionally under-represented backgrounds for whom research and further graduate training is not often obtainable. Participants will make contributions to our fundamental understanding of the interactions between cells and tissues and their surrounding natural or synthetic environment or between drug carriers and their target cells. This Site will specifically investigate the benefit of this training for rising junior undergraduate students from traditionally underrepresented groups with limited research opportunities. The Site will assess the impact of hands-on biomaterials research, faculty and near-peer mentoring, research presentations at local and national meetings, and professional development activities on continued training in biomaterials at the graduate level. Over a three-year period, this REU Site will focus on providing research experiences at the interface of materials science, biological science, and bioengineering via 2 themes: (1) building and testing how bio-inspired niche influence cell behaviors and (2) fabrication of novel drug delivery vehicles to improve delivery of a wide class of drugs. Through a combination of research, biomaterials "boot camp," weekly research skills workshops, professional activities, state-of-the-art facilities, and social functions, the participant cohort will be exposed to graduate education and the ethos of the biotechnology sector present in San Diego. Participants will be matched with one of a dozen participating faculty members and tracked via Individualized Development Plans tailored for each participant to ensure the best possible outcomes for their training and development. Given the breadth and depth of Site faculty, research will appeal to a wide range of students, particularly those entering their junior year who are beginning the in-depth portion of their academic engineering training. Attendance and participation in research conferences and professional meetings will serve as capstone activities of this REU Site to improve awareness of career paths and the value of graduate education. As a result of this Site, we aim to show that the activities listed above, especially when targeted at juniors, can result in higher academic performance in subsequent years in school and in higher entry into graduate training.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

随着社区发现生物材料的新应用和监管，该本科生研究经验 (REU) 网站重点关注生物材料领域不断扩大的研究机会。该网站由加州大学圣地亚哥分校雅各布斯工程学院主办，将为来自传统上代表性不足的背景的各种才华横溢的本科生提供研究机会和专业发展，而这些学生通常无法获得研究和进一步的研究生培训。参与者将为我们对细胞和组织及其周围天然或合成环境之间或药物载体与其靶细胞之间相互作用的基本理解做出贡献。本网站将专门调查这种培训对于来自传统上代表性不足且研究机会有限的群体的初中本科生的好处。该网站将评估生物材料实践研究、教师和近同行指导、地方和国家会议上的研究报告以及专业发展活动对研究生生物材料继续培训的影响。在三年的时间内，该 REU 站点将重点通过两个主题提供材料科学、生物科学和生物工程交叉领域的研究经验：(1) 构建和测试仿生利基如何影响细胞行为；(2) 制造新型药物输送载体以改善多种药物的输送。通过研究、生物材料“训练营”、每周研究技能研讨会、专业活动、最先进的设施和社交活动的结合，参与者群体将接触到研究生教育和圣地亚哥生物技术领域的精神。参与者将与十多名参与教师中的一名进行匹配，并通过为每位参与者量身定制的个性化发展计划进行跟踪，以确保他们的培训和发展取得最佳结果。鉴于现场教师的广度和深度，研究将吸引广泛的学生，特别是那些进入大三、开始深入学术工程培训的学生。出席和参与研究会议和专业会议将作为该 REU 站点的顶峰活动，以提高对职业道路和研究生教育价值的认识。通过本网站，我们旨在表明，上述活动，尤其是针对三年级学生的活动，可以在随后几年的学校学习中取得更高的学业成绩，并提高进入研究生培训的机会。该奖项反映了 NSF 的法定使命，并通过使用基金会的智力价值和更广泛的影响审查标准进行评估，被认为值得支持。