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Fundamental Study of Synthetic and Transformational Reactions of Molecular Silver and Gold Nanoparticles

分子银、金纳米粒子的合成与转化反应的基础研究

基本信息

批准号：
1905262
负责人：
Terry Bigioni
金额：
$ 27万
依托单位：
University of Toledo
依托单位国家：
美国
项目类别：
Standard Grant
财政年份：
2019
资助国家：
美国
起止时间：
2019-08-15 至 2023-07-31
项目状态：
已结题

来源：
https://www.nsf.gov/awardsearch/showAward?AWD_ID=1905262&HistoricalAwards=false
关键词：
Fundamental Study Synthetic Transformational Reactions

项目摘要

Chemists routinely transform molecules using chemical reactions to make and break chemical bonds, rearranging the atoms in controlled and deliberate ways to make new and valuable molecules. The synthesis and transformation of molecular nanoparticles (10-100 times the size of most small molecules) lack that level of control and sophistication. Professor Terry Bigioni and his research group at the University of Toledo are changing this limitation by systematically studying different types of nanoparticle reactions to learn the details of nanoparticle synthesis and transformation. By shedding light on how nanoparticles react, chemists may be able to make better nanomaterials and enable new technologies that drive the economy and help society. The fundamental nature of this work means that it can impact a broad range of fields, such as better catalysts that clean the air and conserve energy, new classes of anti-cancer and anti-viral drugs, light-emitting beacons for biomedical imaging, or energy absorbers for harvesting energy directly from the sun. Students involved in this research gain valuable skills and interdisciplinary training that is vital to strengthening our nation's economy, technical leadership, and workforce. This project includes extensive outreach activities, including the popular "Saturday Morning Science" public lecture series at the University of Toledo.Monolayer-protected clusters (MPCs) are a class of nanoparticles that are small enough to have discrete molecular structures. Despite being a molecular species, it is still not yet possible to predict the outcome of MPC reactions. With support from the Macromolecular, Supramolecular and Nanochemistry program of the NSF Chemistry Division, Professor Terry Bigioni and his research group are studying the fundamental chemical principles of noble metal MPCs (primarily gold, silver, and their alloys), to better understand reactions involving this new class of compounds. The research focuses on learning the synthetic principles of nanoparticle formation as well as the underlying concepts of nanoparticle modification and transformation using a subset of MPCs with known structures. To accomplish this, the team is developing methods to study equilibrium distributions and reaction kinetics in order to gain a more detailed picture of metal nanoparticle thermodynamics and reaction pathways. These are important steps toward establishing a predictive theory of noble metal nanoparticle reactivity and improving our ability to rationally control their structures and properties.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

化学家经常通过化学反应来改变分子，以建立和打破化学键，以受控和有意的方式重新排列原子，以制造新的有价值的分子。分子纳米粒子的合成和转化(是大多数小分子的10-100倍大小)缺乏这种水平的控制和复杂程度。托莱多大学的特里·比吉奥尼教授和他的研究小组正在通过系统地研究不同类型的纳米颗粒反应来了解纳米颗粒合成和转化的细节，从而改变这一限制。通过揭示纳米颗粒是如何反应的，化学家们可能能够制造出更好的纳米材料，并使新技术能够驱动经济和帮助社会。这项工作的基本性质意味着它可以影响广泛的领域，例如清洁空气和节约能源的更好的催化剂、新型抗癌和抗病毒药物、用于生物医学成像的发光信标，或者直接从太阳获取能量的能量吸收器。参与这项研究的学生获得宝贵的技能和跨学科培训，这对加强我们国家的经济、技术领导力和劳动力至关重要。该项目包括广泛的外联活动，包括在托莱多大学举办的广受欢迎的“星期六早上科学”公开讲座系列。单层保护的团簇(MPC)是一类足够小的具有离散分子结构的纳米颗粒。尽管它是一个分子物种，但它仍然不可能预测MPC反应的结果。在NSF化学部大分子、超分子和纳米化学项目的支持下，Terry Bigion i教授和他的研究小组正在研究贵金属MPC(主要是金、银及其合金)的基本化学原理，以更好地了解涉及这类新化合物的反应。这项研究的重点是学习纳米颗粒形成的合成原理，以及使用具有已知结构的MPC的子集进行纳米颗粒修饰和转化的基本概念。为了实现这一目标，该团队正在开发研究平衡分布和反应动力学的方法，以便更详细地了解金属纳米粒子的热力学和反应路径。这些都是建立贵金属纳米粒子反应性预测理论和提高我们合理控制其结构和性能的能力的重要步骤。该奖项反映了NSF的法定使命，并通过使用基金会的智力优势和更广泛的影响审查标准进行评估，被认为值得支持。