The 16th US-Korea Forum on Nanotechnology: Nanomedicine Focusing on Single Cell Level and Sensors Related to Human Cognition and Brain Research

自2003年以来，美韩纳米技术论坛一直在交替的国家举行。论坛的重点是加强两国科学家和工程师在纳米技术转化领域的研究合作。具体地说，联合论坛促进了两国研究界和机构之间的联系，使双方能够交流信息，探索研究合作的机会。今年的主题是专注于单细胞水平的纳米医学，以及与人类认知和大脑研究相关的传感器。该论坛包括来自美国的8名资深演讲者和7名初出茅庐的演讲者，人数大致相同的韩国演讲者也将参加。本届论坛组委会致力于强调多样性。本论坛积极鼓励在纳米技术领域建立伙伴关系，以便在各个主题上取得突破，同时加强成果并评估在前几届论坛期间提出的建议的进展情况。所有论坛的会议记录和调查结果都可以在卡内基梅隆大学的网站上查阅，供广大受众查阅。这个拟议的论坛的贡献是它能够将致力于纳米医学前沿的专家研究人员和创新者的两国社区聚集在一起，专注于与人类认知相关的单细胞水平和传感器。本次论坛将通过充分利用纳米技术向生物信息认知技术的融合，促进上述两个领域的努力。本次论坛的成果将使两国的研究合作具有里程碑意义和活力，纳米技术的融合将产生巨大的影响。随着我们进入第四次工业革命，其特点是技术的融合正在模糊物理、数字和生物领域之间的界限，处理和存储的海量数据的快速增长导致我们需要一个新兴的技术领域，包括人类认知和纳米医学。为了充分探索这些技术，纳米技术与生物信息认知方法的融合发挥了关键作用。在第16届论坛期间，将仔细讨论以下两个主题。(A)侧重于单细胞水平的纳米医学：纳米医学领域当前的挑战涉及：i)新开发材料的长期命运(在空间和时间上的分布)以及如何将已经开发的纳米材料协同地整合到应用中，ii)纳米材料的利基，iii)改变医疗实践的一般范式，iv)精确监测患者进行预防医学，v)个性化医疗，vi)批次间一致性验证，vii)需要更安全的生物材料，以及viii)针对移动部件的能力。由于单细胞纳米医学的重要性，这一主题将在连续的论坛上进行审查。(B)与人类认知和大脑研究有关的传感器：人类行为改变(HPM)的关键技术组成部分是纳米传感器。将研究能够实现高功率微波时代的新功能的新型纳米传感器。这项技术包括图像处理单元和人工智能单元，仅举几例。通过增加感官输入和增强的传感器，HPM最终可以极大地提高人类的日常表现。纳米技术的融合很可能导致新型传感器技术的发展，这些技术可以在HPM中推进，包括视觉、听力、味觉、嗅觉和体感。该奖项反映了NSF的法定使命，并通过使用基金会的智力优势和更广泛的影响审查标准进行评估，被认为值得支持。

Since 2003, the Forum on Nanotechnology Forum between U.S. and Korea has been held at alternating countries. The forum focuses on enhancing research collaboration in the field of nanotechnology conversion among scientists and engineers from both countries. Specifically, a joint forum facilitates networking between the research communities and agencies of both countries, enabling each side to exchange information and explore opportunities for research collaboration. This year the topics are nanomedicine focusing on single-cell level and sensors related to human cognition and brain research. The forum includes 8 senior presenters and 7 early-career presenters from U.S. and roughly equal number of Korean presenters will also participate. Organizing committee of this forum strives to place emphasis on diversity. This forum actively encourages partnerships in nanotechnology for breakthroughs in various topics, in addition to strengthening achievements and assessing the progress on recommendation made during the previous forums. All of the forum proceedings and findings are available on Carnegie Mellon's website for broad audiences. The contribution of this proposed forum is its ability to bring together a bi-national community of expert researchers and innovators who are working on the leading edge of nanomedicine focusing on single cell level and sensors related to human cognition. This forum will stimulate efforts to promote the above two areas by fully utilizing nanotechnology convergence to bio-information-cognitive technology. The outcome of this forum will lead to milestone and vigorous research collaboration of both countries where nanotechnology convergence will generate a great impact. As we enter the 4th industrial revolution, which is characterized by a fusion of technologies that is blurring the lines between the physical, digital, and biological spheres, the rapid increase in the enormous amount of data processed and stored led us to a need for an emerging field of technologies including human cognition and nanomedicine. To fully explore these technologies, nanotechnology convergence with bio-information-cognitive methods play a critical role. The following two topics will be scrutinized during this 16th Forum. (a) Nanomedicine focusing on single cell level: Current challenges in nanomedicine area involve i) long-term fate for newly developed materials (distribution in space and time) and how to integrate already-developed nano-materials into application synergistically, ii) the niche of nanomaterials, iii)changing the general paradigm of medical practice, iv) precisely monitoring patients for preventive medicine, v) personalized medicine, vi) batch-to-batch consistency validation, vii) need for safer biomaterial, and viii) ability to target moving parts. Due to the importance of single-cell nanomedicine, this topic will be examined during the consecutive forums. (B) Sensors related to human cognition and brain research: Key technical components of human performance modification (HPM) are the nanosensors. Novel nanosensors that are capable of new functions allowing an era in HPM will be investigated. This technology includes an image processing unit and an artificial intelligence unit to name a few. With added sensory inputs and augmented sensors, ultimately HPM can drastically enhance human performance on a daily basis. The convergence of nanotechnology is likely to result in the development of novel sensor technologies that can advance in HPM including vision, audition, gustation, olfaction, and somatosensation.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.