FASEB's The Dynamic DNA Structures in Biology Conference

该奖项将支持研究生、博士后和新研究者参加2020年6月7日至12日在加拿大新斯科舍省橡树岛度假村和会议中心举行的美国实验生物学学会联合会（FASEB）会议。会议的重点是独特的DNA结构以及它们如何影响生物和突变过程。本次会议由dr。Lorraine Symington（哥伦比亚大学），Kirill Lobachev（佐治亚理工学院）和Karen Usdin（国立卫生研究院）。会议的形式包括36场邀请演讲，14场从提交的摘要中选出的演讲，以及几场海报会议。此外，Virginia Zakian（普林斯顿大学）和Tom Petes（杜克大学）的两个主题演讲将开始会议。还有两个专门的1小时会议供学员与主要专家互动，并在晚上举行三个单独的海报会议。还将为受训者举办职业讲习班。42%的受邀演讲是女性，组织者和会议主席在从摘要中选择演讲时，会优先考虑研究生、博士后和新研究人员。这次会议还提供了许多（正式和非正式的）机会来分享最近的研究成果和探索合作，并寻求在会议的各个方面包括那些在科学领域代表性不足的人。这是一场关于替代性DNA结构的重要而独特的会议，吸引了许多国内和国际参与者，其中包括许多nsf资助的研究人员。该会议始于2008年，每两年举行一次。这次会议将汇集来自世界各地的不同科学家，重点介绍DNA修复、DNA复制、转录、非规范DNA和DNA- rna结构方面的最新进展。与上次会议相比，选择这个新地点对美国和国际与会者来说都更容易到达。会议主题包括：可扩展重复序列和人类疾病，rna介导的基因组不稳定性，结构诱导的基因组不稳定性，停滞复制叉的动力学，G四联体和端粒，基因编辑，复制和修复结构的单分子分析，染色体重排/脆弱性。会议主要突出未发表的研究成果，并为年轻研究人员提供许多经验，以了解该领域并设计未来的研究途径。这次会议将鼓励新一代研究人员的职业发展，包括那些在科学领域代表性不足的研究人员。该奖项反映了美国国家科学基金会的法定使命，并通过使用基金会的知识价值和更广泛的影响审查标准进行评估，被认为值得支持。

This award will support graduate student, postdoctoral and new investigator attendance at the Federation of American Societies for Experimental Biology (FASEB) meeting at the Oak Island Resort and Conference Center in Nova Scotia, Canada from June 7-12, 2020. The meeting focuses on unique DNA structures and how they affect biological and mutational processes. The meeting is co-organized by Drs. Lorraine Symington (Columbia University), Kirill Lobachev (Georgia Institute of Technology) and Karen Usdin (NIH). The format of the meeting is a combination of 36 invited talks, 14 talks selected from submitted abstracts, and several poster sessions. In addition, two keynote lectures by Virginia Zakian (Princeton University) and Tom Petes (Duke University) will begin the meeting. There are also two dedicated 1-hour sessions for trainees to interact with leading experts and three separate poster sessions held in the evenings. A career-workshop will also be held for trainees. 42% of the invited talks are by women and the organizers and session chairs seek to prioritize graduate students, postdocs and new investigators in the selection of talks chosen from the abstracts. This meeting also affords many opportunities (both formal and informal) for sharing recent research findings and exploring collaborations and seeks to include those underrepresented in science in every aspect of the meeting.This is a premier and unique meeting on alternate DNA structures that draws many national and international participants, and includes many NSF-funded investigators. The meeting began in 2008 and is held every other year. Recent advances in DNA repair, DNA replication, transcription, and non-canonical DNA and DNA-RNA structures will be highlighted in this conference, which will bring together diverse scientists from around the world. This new venue was chosen as a more easily accessible site for both US and international participation than at the last meeting. The session topics include: Expandable Repeats and Human Disease, RNA-mediated Genome Instability, Structure-Induced Genome Instability, Dynamics at Stalled Replication Forks, G quadruplexes and Telomeres, Gene Editing, Single Molecule Analysis of Replication and Repair Structures, and Chromosome Rearrangements/Fragility. The conference primarily highlights unpublished research findings and provides many experiences for young researchers to learn about the field and devise future avenues for research. The meeting will encourage career development of a new generation of researchers, including those who are underrepresented in science.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.