Conference: FASEB Conference on Dynamic DNA Structures in Biology

该奖项将支持研究生、博士后和新研究者参加美国实验生物学学会联合会（FASEB）会议，会议于2024年7月21日至25日在美国墨尔本的墨尔本海滨皇冠假日酒店举行。会议的重点是独特的DNA和RNA结构以及它们如何影响生物和突变过程。本次会议由dr。Kirill Lobachev（佐治亚理工学院）、Karen Usdin（美国国立卫生研究院）、Mitch McVey（塔夫茨大学）和Guy-Franck Richard（巴斯德研究所）。会议的形式包括45场邀请演讲，18场从提交的摘要中选出的演讲，以及几场海报会议。此外，Lorraine Symington（哥伦比亚大学）的主题演讲和peter Cejka （Bellinzona生物医学研究所）的EMBO主题演讲将开始会议。还有一个专门的1小时会议供学员与主要专家互动，以及三个单独的海报会议。还将为受训者举办职业发展讲习班。组织者和会议主席将优先考虑从摘要中选择的研究生，博士后和新研究人员的演讲。这次会议为分享最近的研究成果和探索合作提供了许多正式和非正式的机会，并寻求扩大研究人员在这一领域的参与。这次关于替代性DNA结构的重要而独特的会议吸引了许多国内和国际参与者，其中包括许多nsf资助的研究人员。该会议始于2008年，每两年举行一次。本次会议将重点介绍DNA修复、DNA复制、转录、非规范DNA和DNA- rna结构的最新进展。会议主题包括“DNA结构的生物化学和单分子分析”、“动态DNA分析的新技术”、“结构诱导的基因组不稳定性”、“G四联体和端粒”、“复制和修复的结构分析”、“人类疾病中的可扩展重复序列”、“可扩展重复序列疾病的基因治疗”、“染色体脆弱性”、“转座因子、病毒和寄生虫”和“rna介导的基因组不稳定性”。会议主要突出了未发表的研究成果，并为年轻研究人员提供了许多了解该领域和设计未来研究途径的机会。该项目还为新一代研究人员提供职业发展培训和指导。该项目由生物科学理事会分子和细胞生物科学部的遗传机制项目和分子生物物理学项目共同资助。该奖项反映了美国国家科学基金会的法定使命，并通过使用基金会的知识价值和更广泛的影响审查标准进行评估，被认为值得支持。

This award will support graduate student, postdoctoral and new investigator attendance at the Federation of American Societies for Experimental Biology (FASEB) meeting at Crowne Plaza Melbourne-Oceanfront Hotel, Melbourne, USA from July 21-25, 2024. The meeting focuses on unique DNA and RNA structures and how they affect biological and mutational processes. The meeting is co-organized by Drs. Kirill Lobachev (Georgia Institute of Technology), Karen Usdin (NIH), Mitch McVey (Tufts University) and Guy-Franck Richard (Institut Pasteur). The format of the meeting is a combination of 45 invited talks, 18 talks selected from submitted abstracts, and several poster sessions. In addition, a keynote lecture by Lorraine Symington (Columbia University), and an EMBO keynote lecture by Petr Cejka (Institute for Research in Biomedicine, Bellinzona) will begin the meeting. There is also a dedicated 1-hour session for trainees to interact with leading experts and three separate poster sessions. A career development workshop will also be held for trainees. The organizers and session chairs will prioritize graduate students, postdocs, and new investigators in the selection of talks chosen from the abstracts. This meeting affords many formal and informal opportunities for sharing recent research findings and exploring collaborations, and seeks to broaden participation of researchers in this field.This premier and unique meeting on alternate DNA structures draws many national and international participants, and includes many NSF-funded investigators. The meeting began in 2008 and is held every other year. Recent advances in DNA repair, DNA replication, transcription, and non-canonical DNA and DNA-RNA structures will be highlighted in this conference. The session topics include “Biochemical and Single Molecule Analysis of DNA Structures”, “New Technologies for the Analysis of Dynamic DNA”, “Structure-induced Genome Instability”, “G quadruplexes and Telomeres”, “Structural Analysis of Replication and Repair”, “Expandable Repeats in Human Disorders”, “Gene Therapies for Expandable Repeat Diseases”, “Chromosome Fragility”, “Transposable Elements, Viruses and Parasites”, and “RNA-mediated Genome Instability”. The conference primarily highlights unpublished research findings and provides many opportunities for young researchers to learn about the field and devise future avenues for research. The program also offers career development training and mentoring for a new generation of researchers.This project is jointly funded by the Genetic Mechanisms program and the Molecular Biophysics program in the Division of Molecular and Cellular Biosciences of the Directorate for Biological Sciences.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.