Exploiting Chemical and Structural Tunability to Harness Temperature-Dependent Luminescence at the Nanoscale

利用化学和结构可调性来利用纳米尺度的温度依赖性发光

基本信息

  • 批准号:
    2003118
  • 负责人:
  • 金额:
    $ 45.13万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
    Continuing Grant
  • 财政年份:
    2020
  • 资助国家:
    美国
  • 起止时间:
    2020-07-01 至 2024-06-30
  • 项目状态:
    已结题

项目摘要

The accurate and precise determination of temperature is critical in diagnostic and therapeutic biosystems. Nanomaterials capable of serving as optical temperature sensors are uniquely suited for this task because they are able to operate in environments where contact thermometry cannot be implemented (e.g., cells and deep tissues). However, the vast majority of luminescent nanothermometers lack the required temperature sensitivity. New inorganic nanomaterials with temperature-dependent luminescence response will be discovered and developed in this research. Through a combination of synthesis and characterization studies the rules governing the temperature sensitivity of these phosphors are established. These rules are then used to design optical thermometers with targeted sensitivity within a given temperature window. In addition, this project provides opportunities for workforce development at both undergraduate and graduate levels and K-12 STEM outreach. Graduate and undergraduate students are trained in the synthesis and advanced characterization of luminescent nanomaterials. 6th through 9th grade students participating in the annual STEM Day hosted by Wayne State University are introduced to optical materials research through a hands-on activity based on photostimulable phosphors.The research aims to develop an understanding of how to tune the temperature sensitivity of luminescent nanothermometers by rationally matching hosts and activators. The chemical and structural tunability of a novel family of host materials is exploited to this end. The project can be divided into three thrust areas. The first area involves synthesis of a series of inorganic nanocrystals that incorporate divalent and trivalent metal dopants as luminescent centers. To this end, colloidal synthetic routes to heterocationic and heteroanionic nanocrystals are developed. The second thrust focuses on ascertaining the placement of the luminescent centers in the nanocrystalline hosts. This task involves interrogating the atomic arrangement in multiple length scales using element-specific spectroscopic probes. Finally, in the third thrust, the temperature-dependent luminescence response of the nanocrystals is systematically probed using steady-state and time-dependent spectrofluorometry. Composition–structure–luminescence relationships are then derived to reveal the fundamental chemical and structural principles governing the temperature sensitivity of the nanothermometers.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.
准确和精确的温度测定在诊断和治疗生物系统中至关重要。能够用作光学温度传感器的纳米材料独特地适合于该任务,因为它们能够在不能实施接触式测温的环境中操作(例如,细胞和深层组织)。然而,绝大多数发光纳米温度计缺乏所需的温度灵敏度。本研究将发现和开发具有温度依赖性发光响应的新型无机纳米材料。通过合成和表征的研究相结合的规则,这些磷光体的温度敏感性的建立。然后使用这些规则来设计在给定温度窗口内具有目标灵敏度的光学温度计。此外,该项目还为本科和研究生阶段的劳动力发展以及K-12 STEM外展提供了机会。研究生和本科生在发光纳米材料的合成和先进的表征培训。参加由韦恩州立大学主办的年度STEM日的6至9年级学生通过基于光激励磷光体的动手活动介绍了光学材料研究。该研究旨在了解如何通过合理匹配主机和激活剂来调整发光纳米温度计的温度灵敏度。为此,利用了一种新的宿主材料家族的化学和结构可调性。该项目可分为三个重点领域。第一个领域涉及一系列无机纳米晶体的合成,这些无机纳米晶体将二价和三价金属掺杂剂作为发光中心。为此,胶体合成路线的杂阳离子和杂阴离子纳米晶体的开发。第二个重点是确定纳米晶基质中发光中心的位置。这项任务涉及使用特定元素的光谱探针在多个长度尺度上询问原子排列。最后,在第三个推力,温度依赖的发光响应的纳米晶体系统探测使用稳态和时间依赖的荧光光谱。该奖项反映了NSF的法定使命,并已被认为是值得通过使用基金会的智力价值和更广泛的影响审查标准进行评估的支持。

项目成果

期刊论文数量(5)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
Temperature-dependent luminescence of CaFCl:Yb,Er upconverting nanocrystals
CaFCl:Yb,Er 上转换纳米晶体的温度依赖性发光
  • DOI:
    10.1016/j.jlumin.2021.117974
  • 发表时间:
    2021
  • 期刊:
  • 影响因子:
    3.6
  • 作者:
    Dhanapala, B. Dulani;Munasinghe, Hashini N.;Rabuffetti, Federico A.
  • 通讯作者:
    Rabuffetti, Federico A.
Local atomic environment of Yb 3+ in alkaline-earth fluorohalide nanocrystals
碱土氟卤化物纳米晶中Yb 3 的局域原子环境
  • DOI:
    10.1039/d2ce00636g
  • 发表时间:
    2022
  • 期刊:
  • 影响因子:
    3.1
  • 作者:
    Amarasinghe, Dinesh K.;Dissanayake, K. Tauni;Dhanapala, B. Dulani;Rabuffetti, Federico A.
  • 通讯作者:
    Rabuffetti, Federico A.
Expanding the synthetic toolbox to access pristine and rare-earth-doped BaFBr nanocrystals
  • DOI:
    10.1039/d1dt02694a
  • 发表时间:
    2021-10-12
  • 期刊:
  • 影响因子:
    4
  • 作者:
    Dhanapala, B. Dulani;Munasinghe, Hashini N.;Rabuffetti, Federico A.
  • 通讯作者:
    Rabuffetti, Federico A.
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Federico Rabuffetti其他文献

Federico Rabuffetti的其他文献

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{{ truncateString('Federico Rabuffetti', 18)}}的其他基金

OP: Establishing the Crystallochemical Principles Governing Energy-Transfer Processes in Upconversion Nanocrystals
OP:建立控制上转换纳米晶体能量转移过程的晶体化学原理
  • 批准号:
    1606917
  • 财政年份:
    2016
  • 资助金额:
    $ 45.13万
  • 项目类别:
    Standard Grant

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Chinese Journal of Chemical Engineering
  • 批准号:
    21224004
  • 批准年份:
    2012
  • 资助金额:
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  • 项目类别:
    专项基金项目
Chinese Journal of Chemical Engineering
  • 批准号:
    21024805
  • 批准年份:
    2010
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    23H03559
  • 财政年份:
    2023
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