Retroviral invasion of the koala genome: Where did it come from and what is it doing now that its there?

逆转录病毒入侵考拉基因组：它从哪里来？现在它在那里做什么？

• 批准号: DP0879906
• 负责人: Prof Paul Young
• 金额: $ 17.68万
• 依托单位: The University of Queensland
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2008
• 资助国家: 澳大利亚
• 起止时间: 2008-01-01 至 2011-06-30
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP0879906
• 关键词: Retroviral; invasion; koala; genome; Where

Although some populations of free-ranging koalas are flourishing, many are in decline as a result of habitat loss and disease. We have shown that a recently identified virus that has infected koalas throughout most mainland Australian populations is associated with high rates of cancer in these animals. This project will study the growth properties of this virus and the mechanism by which it causes cancer in order to provide a foundation for developing intervention strategies for protection of this iconic Australian species.

尽管一些自由放养的考拉种群数量繁盛，但由于栖息地丧失和疾病，许多考拉数量正在减少。我们已经证明，最近发现的一种病毒已经感染了澳大利亚大陆大多数种群的考拉，并且与这些动物的高癌症发病率有关。该项目将研究这种病毒的生长特性及其致癌机制，以便为制定保护这一标志性澳大利亚物种的干预策略奠定基础。