Development and commercialization of novel diagnostic assays for the early detection of acute dengue virus infection

用于早期检测急性登革热病毒感染的新型诊断方法的开发和商业化

• 批准号: LP0668437
• 负责人: Prof Paul Young
• 金额: $ 14.01万
• 依托单位: The University of Queensland
• 依托单位国家: 澳大利亚
• 项目类别: Linkage Projects
• 财政年份: 2006
• 资助国家: 澳大利亚
• 起止时间: 2006-09-28 至 2009-09-27
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/LP0668437
• 关键词: Development; commercialization; novel; diagnostic; assays

Dengue is an emerging disease of the tropics and is endemic in more than 100 countries with up to 100 million cases annually. Of these, 500,000 result in dengue haemorrhagic fever (DHF), a serious life-threatening complication of dengue virus infection. Dengue activity in northern Australia has increased in recent years with suggestions that it may be coming endemic in this country. Early diagnosis, using NS1 based assays should facilitate containment of such outbreaks through earlier identification, treatment, isolation and strategic mosquito control.

登革热是一种新出现的热带疾病，在 100 多个国家流行，每年病例数高达 1 亿。其中，500,000 例导致登革出血热 (DHF)，这是登革热病毒感染的一种严重危及生命的并发症。近年来，澳大利亚北部的登革热活动有所增加，有迹象表明该病可能在该国流行。使用基于 NS1 的检测进行早期诊断应有助于通过早期识别、治疗、隔离和战略性蚊子控制来遏制此类疫情的爆发。