Gordon Research Conference on Plant Molecular Biology: Spatial and Temporal Dynamics in Plant Biology, Holderness, New Hampshire, June 14-19, 2020

第28届戈登植物分子生物学研究会议，题为“植物生物学的时空动态”，定于2020年6月14日至19日在新罕布什尔州霍尔德内斯举行。人类面临的挑战是，在可耕地减少和环境恶化的情况下，可持续地为全球90亿至100亿人口提供营养丰富的食物。植物不能移动，因此必须通过适当的反应来应对不断变化和日益紧张的环境。这次会议的重点是植物对环境的实时反应，但在不同的时间尺度上。例如，光感知是快速的（发生在几毫秒内），但许多信号级联在几分钟到几小时内运行。生物生物钟在以天为单位的时间尺度上运作，但对季节感知也至关重要。进化的时间尺度从几年延伸到几千年。植物的环境响应也发生在不同的空间尺度上，从亚细胞和细胞到整个器官和整个植物。此外，植物对环境的反应也受到其相关微生物的影响，其中包括有益和致病的相互作用。了解植物在时间和空间尺度上对环境响应的机制基础是开发作物在面对不断增加和变化的环境胁迫时能够更好地保持甚至提高其生产力的重要的第一步。本次会议的目标是在科学界和广大公众中传播这些见解，以告知和加强农业实践及其欣赏。为了生存，植物必须实时适应不断变化的环境，然而目前的研究通常只捕获了植物响应的一个（单个时间点）快照。本次会议将重点介绍在不同时间和空间尺度上实时跟踪和分析植物动态响应的新方法和方法-从光敏色素光感知的原子动力学，到表观遗传和转录动力学，再到细胞生物学和发育过程的动力学，再到整个植物生理学和进化动力学。将考虑新的建模和统计方法，包括基于时间的研究，这些研究揭示了以前未知的基因网络相互作用，这些相互作用是使用更传统的方法无法识别的。会议的小规模和对讨论的强调提供了一个独特的机会来发展一个社区，这个社区包含了认识到生命，特别是植物生命在时间和空间上的多种不同组织尺度的重要性。植物信号在不同的时间和空间尺度上运作，从植物物种和群落的进化，但有一些共同的逻辑适用，它们的应用丰富和推进了我们的工作，以了解这些尺度上的植物生物学。一个明确的目标是拓宽在GRC中互动的科学家的思维，另一个平行的目标是通过招募具有新技能的新参与者来建立和扩大植物研究界。这一目标与GRC上讨论的具体研究同样重要。该奖项由植物基因组研究计划、综合生物系统部门的植物、真菌和微生物发育机制计划以及分子和细胞生物科学部的细胞动力学和功能集群共同资助。该奖项反映了美国国家科学基金会的法定使命，并通过使用基金会的知识价值和更广泛的影响审查标准进行评估，被认为值得支持。

The 28th Gordon Research Conference on Plant Molecular Biology, entitled “Spatial and Temporal Dynamics in Plant Biology,” is scheduled for June 14-19, 2020 in Holderness, NH. Humanity faces the challenge of providing a global population of 9-10 billion with nourishing food, sustainably, in spite of loss of arable land and environmental degradation. Plants cannot move and so must deal with a changing and increasingly stressful environment by responding in place. This conference focuses on plant responses to their environment in real time, but at different time scales. For example, light perception is rapid (occurs in milliseconds), but many signaling cascades operate over minutes to hours. The biological circadian clock operates on a time scale of days yet is also critical for seasonal perception. Evolutionary time scales extend over years to millennia. Plant environmental responses also occur at different spatial scales, from subcellular and cellular to whole organ and whole plant. Moreover, plant responses to the environment are also influenced by their associated microbes, which include both beneficial and pathogenic interactions. Understanding the mechanistic basis of plant responses to their environment across both temporal and spatial scales is an important first step towards developing crops better able to maintain or even increase their productivity in the face of increasing and changing environmental stresses. The goal of this conference is the dissemination of these insights both within the scientific community and to the greater public to inform and enhance agricultural practice and its appreciation.To survive, plants must adapt to an ever-changing environment in real-time, yet current studies typically capture only a (single time point) snapshot of plant responses. This conference will highlight new methods and approaches to track and analyze dynamic responses in plants in real time, at different temporal and spatial scales – from the atomic dynamics of light perception by phytochrome, through epigenetic and transcription dynamics, to dynamics of cell biological and developmental processes, to whole plant physiology and evolutionary dynamics. Novel modeling and statistical approaches will be considered, including time-based studies, that reveal previously unknown gene-network interactions at a variety of levels that could not be identified using more conventional means. The small scale of the meeting, and the emphasis on discussion offers a unique opportunity to develop a community that embraces the importance of recognizing the multiple distinct scales of organization, both temporal and spatial, at which life, specifically plant life, operates. Plant signaling operates at different temporal and spatial scales from the evolution of plant species and communities, yet there are commonalities of logic that apply, and their application enriches and advances our work to understand plant biology at each of these scales. While one explicit objective is to broaden the thinking of the scientists who interact at this GRC, a parallel objective is to build and broaden the plant research community through the recruitment of new participants with new skill sets. This objective is as important as the specific research discussed at the GRC. This award was co-funded by the Plant Genome Research Program and the Plant, Fungal and Microbial Developmental Mechanisms Program in the Division of Integrative Organismal Systems, and the Cellular Dynamics and Function Cluster in the Division of Molecular and Cellular Biosciences.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.