MRI: Acquisition of a High-Field NMR Spectrometer

该奖项由主要研究仪器和化学研究仪器计划支持。代顿大学正在购买一台配备自动进样器的400 MHz核磁共振（NMR）光谱仪，以支持Jeremy Erb教授和同事弗拉基米尔贝宁。该光谱仪可用于各种领域的研究，例如加速具有重要经济意义的化学反应的研究，以及允许研究生物相关物种的研究。一般来说，NMR光谱是化学家用来阐明分子结构的最有力的工具之一。它用于识别未知物质，表征分子内原子的特定排列，并研究溶液或固态分子之间相互作用的动力学。 NMR光谱仪是代顿大学和附近的辛克莱社区学院化学和生物化学本科生教学、研究和研究培训的一个组成部分。授予NMR光谱仪的目的是加强各级的研究和教育。该收购尤其影响了手性有机磷酸酯及其与农药相关的衍生物合成的立体特异性反应的发现。该仪器也用于研究冷驯化的生物学机制，在南方灰树蛙dryophytes chrysoscelis。此外，该仪器还提供了有助于阻燃剂设计、制备和研究的信息。该光谱仪还用于探索聚合物合成和生物降解机制以及多烯在生物降解中的应用。最后，核磁共振光谱仪也被用于鉴定含有硼二吡咯亚甲基的合成荧光染料。该奖项反映了NSF的法定使命，并通过使用基金会的知识价值和更广泛的影响审查标准进行评估，被认为值得支持。

This award is supported by the Major Research Instrumentation and the Chemistry Research Instrumentation programs. The University of Dayton is acquiring a 400 MHz nuclear magnetic resonance (NMR) spectrometer equipped with an automatic sample changer to support Professor Jeremy Erb and colleague Vladimir Benin. This spectrometer allows research in a variety of fields such as those that accelerate chemical reactions of significant economic importance, as well as those permitting study of biologically relevant species. In general, NMR spectroscopy is one of the most powerful tools available to chemists for the elucidation of the structure of molecules. It is used to identify unknown substances, to characterize specific arrangements of atoms within molecules, and to study the dynamics of interactions between molecules in solution or in the solid state. The NMR spectrometer is an integral part of teaching as well as research and research training of undergraduate students in chemistry and biochemistry at the University of Dayton and nearby Sinclair Community College. The award of the NMR spectrometer is aimed at enhancing research and education at all levels. The acquisition especially impacts discovery of stereospecific reactions for the synthesis of chiral organophosphates and their derivatives of relevance to pesticides. The instrumentation is also used for studying biological mechanisms of cold-acclimation in the southern gray tree frog dryophytes chrysoscelis. In addition, the instrument provides information to aid the design, preparation, and studies of flame retardants. The spectrometer is also used to explore polymer synthesis and biodegradation mechanisms and the use of polyenes in biodegradation. Finally, the NMR spectrometer is also utilized to identify synthetic fluorescent dyes having boron dipyrromethene.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.