Doctoral Dissertation Research: Positioning translational research in the biotech ecosystem: From basic research to more exploitable knowledge
博士论文研究:在生物技术生态系统中定位转化研究:从基础研究到更可利用的知识
基本信息
- 批准号:2022218
- 负责人:
- 金额:$ 1.14万
- 依托单位:
- 依托单位国家:美国
- 项目类别:Standard Grant
- 财政年份:2020
- 资助国家:美国
- 起止时间:2020-09-01 至 2023-06-30
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
Novel scientific discoveries in the biomedical sector do not become viable clinical treatments or commercial products by themselves. There are numerous steps to go through and obstacles to overcome along the complex biomedical developmental process. Translational research has emerged to increase the speed of the conversion process and improve biomedical productivity. Since 2006, the National Institutes of Health (NIH)’s Clinical and Translational Science Awards (CTSA) program has supported over 60 institutions in order to improve the clinical and translational research environment. While current literature examines the effect of the NIH translational research program, the scope of its analysis is generally restricted to publication at the recipient level. This study analyzes the effect of the NIH CTSA program on biotech entrepreneurship by expanding the scope of analysis to a broader level. In addition, this project attempts to identify the effective combinations of conditions for a high level of biotech entrepreneurship with a specific emphasis on the role of translational research. The results will contribute to a more comprehensive understanding of the effect of translational research in the context of biotech entrepreneurial activity and help us to assess the potential benefit of translational research to the public health. The research draws on the entrepreneurial ecosystem approach and the knowledge spillover theory of entrepreneurship to analyze the effects of translational research on biotech entrepreneurship. The overarching analytical framework is that translational research increases biotech entrepreneurship by increasing the commercially exploitable knowledge stock that is available to entrepreneurs. For the empirical testing, the project uses federal innovation programs such as the Small Business Innovation Research as a proxy for biotech entrepreneurship. This study also considers and examines the biomedical patent, among other forms of exploitable knowledge. The empirical methods highlight how having the translational research program makes differences in the outcomes. Data is collected through various sources including federal agencies such as the National Institutes of Health, the National Science Foundation, and the Census Bureau. The findings will be principally disseminated through publication and will contribute to the literature in the translational research and entrepreneurial ecosystem fields. Additionally, federal agencies like the NIH will have access to a careful empirical appraisal of the CTSA program’s contribution to biomedical enterprises.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.
生物医学领域的新科学发现本身并不能成为可行的临床治疗或商业产品。在复杂的生物医学发展过程中,有许多步骤需要经历,也有许多障碍需要克服。为了提高转化过程的速度和提高生物医学生产率,已经出现了转化研究。自2006年以来,美国国立卫生研究院的S临床和转化科学奖(CTSA)计划已经资助了60多家机构,以改善临床和转化研究环境。虽然目前的文献考察了美国国立卫生研究院翻译研究项目的效果,但其分析的范围一般限于接受者层面的出版。本研究通过将分析范围扩展到更广泛的层面来分析NIH CTSA计划对生物技术创业的影响。此外,该项目试图确定高水平生物技术创业的条件的有效组合,并特别强调转化性研究的作用。研究结果将有助于更全面地理解转化研究在生物技术创业活动中的作用,并帮助我们评估转化研究对公众健康的潜在好处。本研究借鉴创业生态系统方法和创业知识溢出理论,分析了转化型研究对生物技术创业的影响。最重要的分析框架是,转化研究通过增加企业家可利用的商业知识储备来增加生物技术企业家精神。在实证测试中,该项目使用了联邦创新项目,如小企业创新研究,作为生物技术创业的代理。这项研究还考虑和审查了生物医学专利,以及其他形式的可开发知识。实证方法强调了翻译研究项目如何在结果中产生差异。数据是通过各种来源收集的,包括联邦机构,如国家卫生研究院、国家科学基金会和人口普查局。这些发现将主要通过出版物传播,并将有助于翻译研究和创业生态系统领域的文献。此外,像NIH这样的联邦机构将有权对CTSA计划对生物医学企业的贡献进行仔细的实证评估。该奖项反映了NSF的法定使命,并通过使用基金会的智力优势和更广泛的影响审查标准进行评估,被认为值得支持。
项目成果
期刊论文数量(2)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
Translational research: from basic research to regional biomedical entrepreneurship
- DOI:10.1007/s11187-022-00676-9
- 发表时间:2022-08-30
- 期刊:
- 影响因子:6.4
- 作者:
- 通讯作者:
Biomedical entrepreneurship in U.S. regions
- DOI:10.1007/s10961-023-09996-8
- 发表时间:2023-02
- 期刊:
- 影响因子:0
- 作者:Sang-Min Park;Nicholas S. Vonortas
- 通讯作者:Sang-Min Park;Nicholas S. Vonortas
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Nicholas Vonortas其他文献
Nicholas Vonortas的其他文献
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{{ truncateString('Nicholas Vonortas', 18)}}的其他基金
Science Policy Research Report: The Use of Research Portfolios in Science Policy
科学政策研究报告:研究组合在科学政策中的运用
- 批准号:
1734829 - 财政年份:2017
- 资助金额:
$ 1.14万 - 项目类别:
Standard Grant
Research and Technology Partnerships: Quantifying Strategic Relationships
研究和技术合作伙伴关系:量化战略关系
- 批准号:
0738112 - 财政年份:2007
- 资助金额:
$ 1.14万 - 项目类别:
Standard Grant
Collaborative Research: Economic Analysis of Intellectual Property Protection Mechanisms for Research Partnerships
合作研究:研究伙伴关系知识产权保护机制的经济分析
- 批准号:
9906140 - 财政年份:1999
- 资助金额:
$ 1.14万 - 项目类别:
Continuing Grant
An Inquiry into Research Joint Ventures of the European Union
欧盟研究合资企业调查
- 批准号:
9616859 - 财政年份:1996
- 资助金额:
$ 1.14万 - 项目类别:
Standard Grant
Research and Development Cooperation in the United States
美国研发合作
- 批准号:
9510909 - 财政年份:1995
- 资助金额:
$ 1.14万 - 项目类别:
Standard Grant
Scientific Visit to Establish Collaboration on Technology Adoption and Implementation: Small and Medium Sized Firms; March 23-28, 1993
科学访问以建立技术采用和实施方面的合作:中小型企业;
- 批准号:
9311992 - 财政年份:1993
- 资助金额:
$ 1.14万 - 项目类别:
Standard Grant
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