2020 SynCell Meeting

2018年，作为NSF十大创意的一部分，举办了一个关于“构建合成细胞”的研讨会（也称为创意实验室），以确定科学和工程前沿的项目，这些项目将使用合成方法从第一个原理构建细胞。已确定并资助了七个这样的项目，通过本提案资助的会议将使成功的团体聚集在一起，讨论自资助开始以来的一年中取得的进展。追求从无生命的化学物质中构建活细胞的目标为推进美国生物技术中的生物制造提供了重要的机会，生物医学和材料研究，并为参与项目的学生和博士后提供独特的教育和培训机会。会议将为美国科学家和生物医学研究人员提供一个论坛，工程师们概述了他们最近的工作，包括创造由具有相反手性的分子组成的细胞，构建人工神经元和构建没有脂质的细胞以及其他尖端合成生物学项目。这次会议将为科学团体之间的研究思想交流提供时间，并为初级和高级科学家提供网络机会。该奖项反映了NSF的法定使命，并通过使用基金会的知识价值和更广泛的影响审查标准进行评估，被认为值得支持。

In 2018, as part of NSF’s 10 Big Ideas, a workshop (also known as an Ideas lab) on ‘Building a Synthetic Cell’ was held to identify projects at the frontiers of science and engineering that would use synthetic approaches to build cells from first principals. Seven such projects were identified and funded and the meeting funded through this proposal will serve to bring the successful groups together to discuss their progress in the year since funding began. Pursuing the goal of building living cells from inanimate chemistry provides significant opportunities to advance US bio-manufacturing in biotechnology, biomedicine and materials research as well as providing a unique educational and training opportunity for students and post-docs involved in the projects.The meeting will provide a forum for US scientists and bio-engineers to outline their most recent work on creating cells comprised of molecules with opposite chirality, building artificial neurons and constructing cells without lipids among other cutting edge synthetic biology projects. The meeting will allow time for the exchange of research ideas between scientific groups and networking opportunities for both junior and senior scientists.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.