IIBR Instrumentation: All Reflective Microscopy for Biological Research

IIBR 仪器：用于生物研究的全反射显微镜

• 批准号: 2034210
• 负责人: Rongguang Liang
• 金额: $ 64.87万
• 依托单位: University of Arizona
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-03-15 至 2025-02-28
• 项目状态: 未结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2034210&HistoricalAwards=false
• 关键词: IIBR; Instrumentation; Reflective; Microscopy; Biological

An award is made to James C Wyant College, The University of Arizona, to develop a high- performance reflective microscope for biological research. This project will advance biological research by simplifying the microscopic imaging system and enabling new biological data collection not previously possible. The microscope design will enable a better understanding of subcellular structures and cellular processes. It will also have major societal impacts through research, education, and research training of the future U.S. research workforce on instrumentation innovation and biological sciences. The innovation project will address unmet needs for microscope imaging for biological research. The microscope will provide new capabilities for high-resolution imaging across the spectrum from UV to far-IR. The new microscope will not only simplify the configurations of the current multimodal imaging systems and data acquisition process over a wide spectral range, but also open new doors to biological research not possible with current refractive and reflective microscopes. The new imaging modality will enhance methods for current biological data collection and enable the collection of new biological data and information to generate knowledge and advance the field of biology.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

亚利桑那大学詹姆斯·C·怀恩特学院被授予为生物研究开发高性能反射显微镜的奖项。该项目将通过简化显微成像系统和实现以前无法实现的新的生物数据收集来促进生物学研究。显微镜的设计将使人们能够更好地了解亚细胞结构和细胞过程。它还将通过研究、教育和未来美国研究人员在仪器创新和生物科学方面的研究培训，产生重大的社会影响。该创新项目将解决生物研究对显微镜成像的未得到满足的需求。该显微镜将为从紫外线到远红外光谱的高分辨率成像提供新的能力。这种新型显微镜不仅将简化当前多模式成像系统的配置和宽光谱范围内的数据采集过程，而且还将为生物研究打开新的大门，这是目前的折射和反射显微镜无法实现的。新的成像模式将增强当前生物数据收集的方法，并使收集新的生物数据和信息能够产生知识并推动生物领域的发展。该奖项反映了NSF的法定使命，并通过使用基金会的智力优势和更广泛的影响审查标准进行评估，被认为值得支持。