PFI-TT: Organic innovation in phenylalanine-containing seed coatings and treatments to maximize crops of economic importance

创新伙伴关系-技术转化（PFI-TT）项目的更广泛影响/商业潜力为更可持续的农业实践提供了替代产品。这项技术开发和商业化项目的预期成果预计将减少有害生物的压力，增加粮食安全，改善社区经济和环境的稳定性。参与测试拟议技术的种植者将提供有关治疗方式的反馈，为商业化进程奠定基础。行业和学术人员将积极指导项目招募的研究生和本科生，努力招募STEM中代表性不足的学生。研究生和本科生的创业培训和领导力发展将包括对食品和农业科学和商业的沉浸。本科生将有独立的项目，有助于整体项目方向。所有学生都将参与提供培训和就业机会网络的农业社区。拟议的转化研究项目将开发对植物生命周期生长过程有不同影响的材料。抗药性害虫的数量正在增长，它们的管理在美国造成了数十亿美元的收入损失，同时造成了健康问题和环境侵蚀。实现可持续和有效的害虫治疗的障碍包括寻找新的诸如抗性育种的方法，这造成了瓶颈：害虫种群的适应速度超过了解决方案的速度。本项目有三个目标：1)设计针对大豆囊线虫等有害生物的单一和组合产品；2)在不同状态和不同土壤类型的现场场地，在现场条件下测试最有希望的原型；3)将有效的产品商业化，以解决造成作物损失的害虫。提出的方法可以在发育，细胞和生化水平上解决害虫相互作用的反应，以使产品配方失调和破坏已知害虫。通过开发利用植物和害虫生长策略的产品，该项目可能揭示植物生物合成和防御途径之间的作用机制或合作机制，从而改善害虫的综合治理。该奖项反映了美国国家科学基金会的法定使命，并通过使用基金会的知识价值和更广泛的影响审查标准进行评估，被认为值得支持。

The broader impact/commercial potential of this Partnerships for Innovation - Technology Translation (PFI-TT) project offers alternative products for more sustainable farming practices. The expected outcome of this technology development and commercialization project is expected to reduce pest pressures and increase food security, improving community economic and environmental stability. Growers involved in testing the proposed technology will give feedback on treatment modalities to provide a foundation for commercialization processes. Industry and academic personnel will actively mentor graduate students and undergraduates recruited to the project, with efforts to recruit underrepresented students in STEM. Entrepreneurial training and leadership development of graduate and undergraduate students will consist of immersion in the science and business of food and agriculture. Undergraduate students will have independent projects that contribute to the overall project direction. All students will be involved in the agricultural community which provides a network of training and employment opportunities.The proposed translational research project will develop materials that differentially affect growth processes in the plant life cycle. Resistant pest populations are growing and their management costs billions in lost revenue in the US while contributing to health problems and environmental erosion. Hurdles to attaining sustainable and effective pest treatments include finding novel such as breeding for resistances have created bottlenecks: pest populations adaptations are outpacing the solutions. There are three objectives to this project: 1) Design single and combinatorial products that target pests like soybean cyst nematode; 2) Test the most promising prototypes under field conditions at field sites in various states and across soil types; and 3) Commercialize effective products to address the pests that cause crop loss. The proposed methods may address responses of pest interaction at developmental, cellular and biochemical levels to make products formulated to dysregulate and disrupt known pests. By developing products to exploit plant and pest growth strategies, the project may reveal mechanism(s) of action or a cooperative mechanism between plant biosynthesis and defense pathways, leading to improvements to integrated pest management.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.