CAS:Toward Iron Olefin Metathesis: Synthesis and Reactivity of Iron Carbenes

CAS：铁烯烃复分解：铁卡宾的合成和反应性

• 批准号: 2102517
• 负责人: Vlad Iluc
• 金额: $ 47.5万
• 依托单位: University of Notre Dame
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-08-15 至 2024-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2102517&HistoricalAwards=false
• 关键词: CAS; Toward; Iron; Olefin; Metathesis

With the support of the Chemical Catalysis program in the Division of Chemistry, Vlad M. Iluc of Notre Dame University will study an important chemical transformation known olefin metathesis, using earth-abundant transition metal catalysts. The olefin metathesis reaction positively impacts numerous fields in academic research and industry, ranging from synthesis of value-added compounds to applications in materials science and biology. Catalysts currently employed utilize rather costly transition metals such as ruthenium. The proposed research seeks to fundamentally change this approach and could have a significant component of sustainable chemistry as an effective olefin metathesis reaction based upon an earth-abundant metal such as iron would reduce dependence on precious and toxic metals. Dr. Iluc and his team will integrate their scientific activities and results with the Center for Sustainable Energy at Notre Dame (ND Energy) and share their discoveries with the broader research community. The Iluc research group will work to enhance diversity in science by attracting women and underrepresented minorities to work on the proposed projects. The PI and several group members will continue their in person mentorship of teenagers at the Bashor Children’s Home, a non-profit child welfare agency that provides assistance to troubled children and their families through residential care, and help with alternative education and other activities.Vlad M. Iluc and his team at the University of Notre Dame will work to develop an alternative manifold for olefin metathesis based upon earth-abundant metal catalysts. Olefin metathesis reactions are well known for ruthenium catalysis, but those that utilize iron are only now being discovered. Recent workroom the Iluc group demonstrating that iron carbenes can mediate olefin metathesis reactions similar to ruthenium lay the foundation for the proposed work. The results from this project will likely provide foundational insight to guide future developments in iron olefin metathesis catalysis. In this project, Dr. Iluc and his coworkers will investigate the electronic structures and chemical reactivity of tethered iron carbene complexes and apply this knowledge to the synthesis and isolation of mono-tethered and untethered analogues for new catalytic applications. This research program is designed to increase broader participation in STEM through team-coordinated outreach activities.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

在化学催化计划的支持下，巴黎圣母院大学的弗拉德·伊卢克（Vlad M.Iluc）将使用土壤丰富的过渡金属催化剂研究重要的化学转化已知烯烃元件。烯烃的分解反应对学术研究和行业的众多领域产生了积极影响，从增值化合物到材料科学和生物学中的应用。目前使用的催化剂利用诸如氟森等相当昂贵的过渡金属。拟议的研究旨在从根本上改变这种方法，并可能具有可持续化学的重要组成部分，作为基于地球丰富金属（例如铁）（例如铁）的有效烯烃化学反应，将减少对珍贵和有毒金属的依赖。 ILUC博士和他的团队将将他们的科学活动和结果与巴黎圣母院（ND Energy）的可持续能源中心融合在一起，并与更广泛的研究社区分享他们的发现。 ILUC研究小组将通过吸引妇女和代表性不足的少数群体从事拟议项目来提高科学的多样性。 The PI and several group members will continue their in person mentality of teenagers at the Bashor Children’s Home, a non-profit child welfare agency that provides assistance to troubled children and their families through residents care, and help with alternative education and other activities.Vlad M. Iluc and his team at the University of Notre Dame will work to develop an alternative manifold for olefin metathesis based upon earth-abundant metal catalysts.烯烃的分解反应以钌催化而闻名，但是那些利用铁的反应才被发现。最近的工作室ILUC组表明，铁碳纤维可以介导类似于ruthenium的烯烃化学反应为拟议的工作奠定了基础。该项目的结果可能会提供基本的见解，以指导铁烯烃催化剂的未来发展。在这个项目中，ILUC博士和他的同事将研究束缚铁碳纤维络合物的电子结构和化学反应性，并将这些知识应用于新催化应用的单螺旋和不束缚的类似物的合成和隔离。该研究计划旨在通过团队协调的外展活动来增加对STEM的广泛参与。该奖项反映了NSF的法定任务，并使用基金会的知识分子优点和更广泛的影响标准通过评估来诚实地获得支持。