CAREER: Controlling Polymer Degradation, Microstructures, and Sequences via Living Alternating Polymerization of Cyclopropenes and Low-Strain Cyclic Olefins

职业：通过环丙烯和低应变环烯烃的活性交替聚合来控制聚合物降解、微观结构和序列

• 批准号: 1553780
• 负责人: Yan Xia
• 金额: $ 67.5万
• 依托单位: Stanford University
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-03-01 至 2021-09-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1553780&HistoricalAwards=false
• 关键词: CAREER; Controlling; Polymer; Degradation; Microstructures

Polymers are ubiquitous and serve as important and versatile materials in a myriad of societal sectors, and their properties are dictated by the polymer structures. In this project funded by the Macromolecular, Supramolecular and Nanochemistry Program of the Chemistry Division, Prof. Yan Xia of Stanford University develops new synthetic strategies to collectively address the challenges in controlling polymer structure, functionality and degradability. Fundamental studies and method development of this project aim to enable the synthesis of highly functionalized and precisely structured polymers with tailored properties. This project provides valuable training experiences for undergraduate and graduate students to continue to advance our ability to synthesize complex macromolecular structures. This program integrates educational endeavors at several levels to 1) use after-school educational activities and social media to facilitate recruitment and retention of high school students, especially underrepresented students in the Bay Area; 2) enhance the public awareness of soft materials, both commodity and high-end plastics, enabled by new chemistry and engineering; 3) interface organic chemistry with materials science in undergraduate and graduate education to cultivate interdisciplinary researchers.The goal of this research is to provide new insights of metathesis chemistry, new patterns of monomer reactivity, and new synthetic strategies to prepare well-defined polymers and materials with tailored properties. This project develops living alternating ring-opening metathesis polymerization (AROMP) and thermodynamically driven single monomer additions to control polymer backbone and side chain functionalities, microstructures, and monomer sequences. The approach to tune materials properties and assembly behaviors of the resulting polymers is by controlling the structural regularity.It also integrates broader educational endeavors to: 1) facilitate recruitment and retention of underrepresented students in the Bay Area in science majors through local visits and social media; 2) enhance the public awareness of both commodity and high-end plastics enabled by new chemistry; and 3) interface organic chemistry with polymer science in Stanford undergraduate courses to cultivate future interdisciplinary researchers.

聚合物是无处不在的，并作为重要的和多功能的材料在无数的社会部门，其性质是由聚合物的结构。 在这个由化学系高分子、超分子和纳米化学项目资助的项目中，斯坦福大学的Yan Xia教授开发了新的合成策略，以共同应对控制聚合物结构、功能和降解性的挑战。 该项目的基础研究和方法开发旨在合成具有定制特性的高度官能化和精确结构的聚合物。该项目为本科生和研究生提供了宝贵的培训经验，以继续提高我们合成复杂大分子结构的能力。该计划整合了多个层面的教育工作，以1）利用课后教育活动和社交媒体促进高中生的招聘和保留，特别是湾区代表性不足的学生; 2）通过新的化学和工程技术，提高公众对软材料（商品和高端塑料）的认识; 3）在本科和研究生教育中将有机化学与材料科学相结合，培养跨学科的研究人员。本研究的目标是提供复分解化学的新见解，单体反应性的新模式，以及新的合成策略，以制备具有定制特性的明确定义的聚合物和材料。该项目开发了活性交替开环易位聚合（AROMP）和手性驱动的单单体加成，以控制聚合物主链和侧链的官能度、微观结构和单体序列。通过控制聚合物的结构规则性，调整材料性能和聚合物组装行为的方法，并结合更广泛的教育努力：1）通过当地访问和社交媒体，促进湾区理工科专业学生的招聘和保留; 2）通过新化学提高公众对商品和高端塑料的认识; 3）通过新化学提高公众对商品和高端塑料的认识。3）在斯坦福大学本科课程中将有机化学与高分子科学相结合，以培养未来的跨学科研究人员。