MRI: Acquisition of a Modern Single Crystal X-ray Diffractometer for Research and Education

MRI：购买现代单晶 X 射线衍射仪用于研究和教育

• 批准号: 2117287
• 负责人: Wei You
• 金额: $ 27.89万
• 依托单位: University of North Carolina at Chapel Hill
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-08-01 至 2024-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2117287&HistoricalAwards=false
• 关键词: MRI; Acquisition; Modern; Single; Crystal

This award is supported by the Major Research Instrumentation and the Chemistry Research Instrumentation programs. The University of North Carolina at Chapel Hill is acquiring a single crystal X-ray diffractometer (SCXRD) to support Professor Wei You and colleagues Jeffrey Johnson, Alexander Miller, Jillian Dempsey and Aleksandr Zhukhovitskiy. In general, an X-ray diffractometer allows for the accurate and precise determination of the full three-dimensional structure of a molecule, including bond distances and angles, and provides accurate information about the spatial arrangement of a molecule relative to neighboring molecules in the crystal lattice. The studies described here impact many areas, including organic and inorganic chemistry, materials chemistry, solar fuel production and biochemistry. This instrument is an integral part of teaching as well as research and research training of undergraduate and graduate students in chemistry and biochemistry at this institution as well as collaborators from other regional universities such as the University of North Carolina Greensboro, North Carolina Central University, Duke University, Elon University, Davidson College and East Carolina University.The award of this diffractometer is aimed at enhancing research and education at all levels. It especially impacts the development of chemical reactions and deployment of reaction strategies for the synthesis of bioactive natural products with an emphasis on sustainable catalysis. The instrumentation is used in the development of approaches to the sustainable synthesis of chemical building blocks and fuels and for improving efficiency in solar fuel production by optimizing fundamental electron transfer processes. In addition, it benefits studies of high-valent iron-oxo porphyrins that perform selective hydroxylations of unactivated sp3 hybridized carbon-hydrogen bonds and studies developing asymmetric methods for enantioselective synthesis of lactones and hydroxy esters. This diffractometer also benefits the exploration of catalysis for conjugated polymer synthesis, and the creation of optoelectronic devices through the development of hybrid perovskites.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

该奖项由主要研究仪器和化学研究仪器计划支持。位于查佩尔山的北卡罗来纳州大学正在购买一台单晶X射线衍射仪（SCXRD），以支持Wei You教授及其同事Jeffrey约翰逊、亚历山大米勒、Jillian Dempsey和Aleksandr Zhukhovitskiy。通常，X射线衍射仪允许准确和精确地确定分子的完整三维结构，包括键距和角度，并提供关于分子相对于晶格中相邻分子的空间排列的准确信息。这里描述的研究影响了许多领域，包括有机和无机化学，材料化学，太阳能燃料生产和生物化学。该仪器是该机构化学和生物化学本科生和研究生教学、研究和研究培训的组成部分，也是其他地区大学的合作者，如北卡罗来纳州格林斯伯勒大学、北卡罗来纳州中央大学、杜克大学、埃隆大学、戴维森学院和东卡罗莱纳大学。该衍射仪的获奖旨在加强各级的研究和教育。它特别影响化学反应的发展和反应策略的部署，以合成具有生物活性的天然产物，重点是可持续催化。该仪器用于开发化学构件和燃料的可持续合成方法，并通过优化基本电子转移过程提高太阳能燃料生产效率。此外，它有利于研究高价铁氧卟啉，执行未活化的sp3杂化碳-氢键的选择性羟基化和研究开发不对称方法的不对称合成内酯和羟基酯。该衍射仪还有利于共轭聚合物合成催化剂的探索，以及通过混合钙钛矿的开发创造光电器件。该奖项反映了NSF的法定使命，并通过使用基金会的知识价值和更广泛的影响审查标准进行评估，被认为值得支持。

项目成果

Visible light induced formation of a tungsten hydride complex

可见光诱导氢化钨络合物的形成

• DOI: 10.1039/d2dt03675d
• 发表时间: 2023
• 期刊: Dalton Transactions
• 影响因子: 4
• 作者: Isaacs, Diane P.;Gruninger, Cole T.;Huang, Tao;Jordan, Aldo M.;Nicholas, Genique;Chen, Chun-Hsing;ter Horst, Marc A.;Dempsey, Jillian L.
• 通讯作者: Dempsey, Jillian L.