PFI-TT: Strengthening Agriculture Through Better Disease Detection

PFI-TT：通过更好的疾病检测加强农业

• 批准号: 2122686
• 负责人: Kitty Cardwell
• 金额: $ 25万
• 依托单位: Oklahoma State University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-07-15 至 2024-09-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2122686&HistoricalAwards=false
• 关键词: PFI; TT; Strengthening; Agriculture; Through

The broader impact/commercial potential of this Partnerships for Innovation - Technology Translation (PFI-TT) project is the improvement in disease diagnostics. The proposed technology provides a process for the rapid development and optimization of diagnostic tests. The results will be available on a website for use by subscribers in laboratories anywhere in the world. The proposed testing platform technology is entirely virtual and does not need shipping, thus saving significant time and costs. Once the proposed technology is verified, recognized, and in wide use, it will have the potential to be made portable for field, pen, or bedside testing. The proposed technology can test for multiple pathogens in one sample. The system works on plant, animal and human diseases.This project will initially focus on the needs of the citrus industry. Citrus planting materials are shipped all around the world. However, before planting material can enter a country, it has to go through extensive testing to ensure that it isn’t carrying any citrus disease from some other part of the world. The U.S. tests all citrus varieties for up to 30 different disease causing viroids, viruses, bacteria, and fungi. The testing and ‘curing’ of this valuable planting material can take years with available technologies. This technology platform enables researchers to test for all pathogens in a single sample, saving significant time and reducing costs. The research objectives of this project are to develop diagnostic test probes for citrus pathogens of concern to the U.S. and test them in parallel with the currently used standard.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

该创新-技术转化伙伴关系（PFI-TT）项目的更广泛影响/商业潜力是改进疾病诊断。所提出的技术提供了用于快速开发和优化诊断测试的过程。研究结果将在一个网站上公布，供世界各地实验室的订户使用。 所提出的测试平台技术完全是虚拟的，不需要运输，从而节省了大量的时间和成本。一旦所提出的技术得到验证、认可并广泛使用，它将有可能变得便携，用于现场、笔式或床边测试。 该技术可以在一个样本中检测多种病原体。 该系统针对植物、动物和人类疾病，该项目最初将侧重于柑橘业的需要。柑橘种植材料运往世界各地。 然而，在种植材料进入一个国家之前，它必须经过广泛的测试，以确保它没有携带任何来自世界其他地方的柑橘疾病。 美国测试所有柑橘品种多达30种不同的疾病引起类病毒，病毒，细菌和真菌。 利用现有技术，这种宝贵的种植材料的测试和“固化”可能需要数年时间。 该技术平台使研究人员能够在单个样本中测试所有病原体，从而节省大量时间并降低成本。 该项目的研究目标是开发美国关注的柑橘病原体的诊断测试探针，并与目前使用的标准进行平行测试。该奖项反映了NSF的法定使命，并通过使用基金会的知识价值和更广泛的影响审查标准进行评估，被认为值得支持。