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NSF-BSF Application: Developing Sustainable Approaches for Cometabolic Degradation of TCE and cDCE in Groundwater through Stable Isotope Techniques

NSF-BSF 应用：通过稳定同位素技术开发地下水中 TCE 和 cDCE 共代谢降解的可持续方法

基本信息

批准号：
2129228
负责人：
Alison Cupples
金额：
$ 26.96万
依托单位：
Michigan State University
依托单位国家：
美国
项目类别：
Standard Grant
财政年份：
2021
资助国家：
美国
起止时间：
2021-08-15 至 2025-07-31
项目状态：
未结题

来源：
https://www.nsf.gov/awardsearch/showAward?AWD_ID=2129228&HistoricalAwards=false
关键词：
NSF BSF Application Developing Sustainable

项目摘要

Groundwater contamination remains a significant global problem because of the risk to human health from drinking contaminated water. Increasing water scarcity has led to an urgent need for effective and inexpensive approaches to treat contaminated groundwater. The goal of this project is to address this need using innovative monitoring methods to determine the most appropriate approach. This research project by an international collaboration of researchers from Michigan State University and Ben Gurion University will develop a biological treatment approach called ‘bioremediation’ to remove two of the most common groundwater contaminants. The research will advance understanding of bioremediation through novel state-of-the-science chemical and biological analytical techniques. Successful development of efficient and low-cost treatment technology will benefit society by increasing availability of clean water. Additional benefits result from the training of underrepresented students in engineering, thus strengthening and diversifying the Nation’s STEM workforce. This research is jointly funded by NSF and The US-Israel Binational Science foundation through the special submission opportunity NSF 20-094.The goal of this project is to enhance the aerobic bioremediation of the important groundwater contaminants trichloroethene [TCE] and cis-dichloroethene [cDCE]. This goal will be achieved by specific research designed to elucidate which microorganisms provide the most sustainable rates of co-metabolic biodegradation of TCE and cDCE, as well as co-metabolic substrate uptake. The fate of carbon from both the co-metabolic substrates as well as TCE, cDCE, and their degradation products will be assessed using stable isotope probing (SIP). SIP will be combined with compound specific isotope analysis (CSIA) to determine isotope enrichment patterns for these transformations using the complementary expertise and facilities of the U.S. and Israeli research teams. The approach of using both SIP and CSIA will allow for the first time the identification of biodegradation pathways and responsible microorganisms in the field. Successful completion of this research will transform our ability to identify the most sustainable bioremediation scenarios and facilitate elucidation of removal mechanisms in situ. Such data will enable remediation professionals to predict contaminant removal times and assess treatment scenarios more accurately. The research has strong potential to benefit society because these chemicals are major groundwater contaminants across a large number of aquifers in the U.S., Israel, and many other countries.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

地下水污染仍然是一个严重的全球问题，因为饮用受污染的水对人类健康构成风险。日益严重的缺水导致迫切需要有效和廉价的方法来处理受污染的地下水。该项目的目标是利用创新的监测方法来确定最适当的办法，以满足这一需要。这项由密歇根州立大学和本古里安大学的研究人员组成的国际合作研究项目将开发一种名为生物修复的生物处理方法，以去除两种最常见的地下水污染物。这项研究将通过新的最先进的化学和生物分析技术促进对生物修复的理解。高效和低成本处理技术的成功开发将通过增加清洁水的可获得性而造福社会。对人数不足的学生进行工程学方面的培训带来了额外的好处，从而加强了该国的STEM劳动力并使之多样化。这项研究是由美国国家科学基金会和美国-以色列两国科学基金会通过特别提交机会NSF 20-094共同资助的。该项目的目标是加强对重要地下水污染物三氯乙烯[TCE]和顺式二氯乙烯[cDCE]的好氧生物修复。这一目标将通过旨在阐明哪些微生物提供最可持续的TCE和cDCE共代谢生物降解率以及共代谢底物吸收的具体研究来实现。将使用稳定同位素探测(SIP)来评估来自共代谢底物以及TCE、cDCE及其降解产物的碳的去向。Sip将与化合物特定同位素分析(CSIA)相结合，利用美国和以色列研究团队的互补专业知识和设施，确定这些转化的同位素浓缩模式。同时使用SIP和CSIA的方法将首次能够确定实地的生物降解途径和负责任的微生物。这项研究的成功完成将改变我们识别最可持续的生物修复方案的能力，并促进现场清除机制的阐明。这些数据将使补救专业人员能够预测污染物清除时间，并更准确地评估处理方案。这项研究具有很强的造福社会的潜力，因为这些化学物质是美国、以色列和许多其他国家大量含水层的主要地下水污染物。这一奖项反映了NSF的法定使命，并通过使用基金会的智力优势和更广泛的影响审查标准进行评估，被认为值得支持。