Conference: Genetic Recombination and Genome Rearrangments FASEB Summer Research Conference

该奖项是为了支持将于2022年8月14日至19日在科罗拉多州蒸汽船泉举行的基因重组和基因组重排会议。这是一个成熟的会议，自1985年以来每两年举行一次。会议将包括8次全体会议，每次会议将有6至8次20分钟的发言。三分之二的演讲者是受邀的，其余的将来自投稿摘要，重点是早期职业科学家。这次会议将有200多名与会者，他们代表了从实习生到成熟的PI的所有职业阶段。委员会将特别努力为不同的青年科学家提供全体发言机会和简短的海报演讲。值得注意的是，所有NSF资金将用于支持受训者和年轻研究人员的参与，重点是那些来自代表性不足的群体以及有经济需要的群体。会议将集中讨论重组及其对染色体分离、DNA修复、基因组重排和突变的影响。这些主题将从多个角度进行探讨，包括重组中涉及的蛋白质的结构和生物物理分析，以及重组对基因组结构的影响的基因组分析。会议将强调结构生物学、分子遗传学和生物化学的前沿方法在DNA损伤反应、染色质重塑以及复制和重组的一般过程中的应用所带来的突破。该奖项反映了美国国家科学基金会的法定使命，并通过使用基金会的知识价值和更广泛的影响审查标准进行评估，被认为值得支持。

This award is for support of the conference Genetic Recombination and Genome Rearrangements, to be held August 14-19, 2022 in Steamboat Springs, Colorado. This is a well-established conference that has occurred biennially since 1985. The meeting will include 8 plenary sessions, each of which will have 6 to 8 20 minute presentations. Two thirds of the speakers are by invitation, and the remainder will be from contributed abstracts, with an emphasis on early career scientists. This meeting will have over 200 participants representing all career stages, from trainees to established PI’s. The committee will make a special effort to provide plenary speaking opportunities and short poster talks to diverse junior scientists as well. Notably, all NSF funds will be used to support participation by trainees and young investigators, with an emphasis on those from under-represented groups as well as those with financial need. The conference will focus on the topic of recombination and its implications for chromosome segregation, DNA repair, genome rearrangement, and mutation. These topics will be explored from multiple perspectives,including structural and biophysical analyses of the proteins involved in recombination, and genomic analyses of the consequences of recombination for genome structure. The meeting will emphasize breakthroughs spurred by cutting-edge approaches from structural biology, molecular genetics, and biochemistry as applied to DNA damage responses, chromatin remodeling, and the general processes of replication and recombination.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.