Conference: Genetic Recombination and Genome Rearrangments FASEB Summer Research Conference

该奖项是为支持会议遗传修饰和基因组重排，将于2022年8月14日至19日在汽船泉，科罗拉多. 这是一个自1985年以来每两年举行一次的既定会议。会议将包括8场全体会议，每场会议将有6至8场20分钟的演讲。三分之二的演讲者是应邀而来的，其余的将来自贡献的摘要，重点是早期的职业科学家。本次会议将有200多名代表所有职业阶段的与会者，从受训人员到已建立的PI。该委员会将作出特别努力，为不同的年轻科学家提供全体演讲机会和简短的海报演讲。值得注意的是，NSF的所有资金将用于支持受训人员和年轻研究人员的参与，重点是那些代表性不足的群体以及那些有经济需要的人。会议将集中讨论重组及其对染色体分离、DNA修复、基因组重排和突变的影响。这些主题将从多个角度进行探讨，包括重组中涉及的蛋白质的结构和生物物理分析，以及重组对基因组结构的影响的基因组分析。会议将重点关注应用于DNA损伤反应、染色质重塑以及复制和重组的一般过程的结构生物学、分子遗传学和生物化学前沿方法所带来的突破。该奖项反映了NSF的法定使命，并通过使用基金会的智力价值和更广泛的影响审查标准进行评估，被认为值得支持。

This award is for support of the conference Genetic Recombination and Genome Rearrangements, to be held August 14-19, 2022 in Steamboat Springs, Colorado. This is a well-established conference that has occurred biennially since 1985. The meeting will include 8 plenary sessions, each of which will have 6 to 8 20 minute presentations. Two thirds of the speakers are by invitation, and the remainder will be from contributed abstracts, with an emphasis on early career scientists. This meeting will have over 200 participants representing all career stages, from trainees to established PI’s. The committee will make a special effort to provide plenary speaking opportunities and short poster talks to diverse junior scientists as well. Notably, all NSF funds will be used to support participation by trainees and young investigators, with an emphasis on those from under-represented groups as well as those with financial need. The conference will focus on the topic of recombination and its implications for chromosome segregation, DNA repair, genome rearrangement, and mutation. These topics will be explored from multiple perspectives,including structural and biophysical analyses of the proteins involved in recombination, and genomic analyses of the consequences of recombination for genome structure. The meeting will emphasize breakthroughs spurred by cutting-edge approaches from structural biology, molecular genetics, and biochemistry as applied to DNA damage responses, chromatin remodeling, and the general processes of replication and recombination.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.