RUI: Experimental Studies of Active Mixing in Extended Fluid Systems
RUI:扩展流体系统中主动混合的实验研究
基本信息
- 批准号:2302708
- 负责人:
- 金额:$ 19.49万
- 依托单位:
- 依托单位国家:美国
- 项目类别:Standard Grant
- 财政年份:2023
- 资助国家:美国
- 起止时间:2023-07-01 至 2026-06-30
- 项目状态:未结题
- 来源:
- 关键词:
项目摘要
Non-Technical AbstractExperiments in this project explore the effects of fluid flows on “active” agents such as swimming organisms and moving reaction fronts. Fluid flows are everywhere in nature and in technology, including in living organisms; in rivers, lakes and oceans; in the atmosphere and in stars; in numerous industrial processes; and even in “flows” of people in society. These experiments test predictions that fluid mixing can synchronize the growth of microbial colonies, similar to the rapid “blooming” of algae in the oceans; that mixing patterns in the flow can affect the formation of biofilms on surfaces; that the combination of swimming and the fluid flow can result in “chaotic” trajectories; and that flows can enhance – and sometimes inhibit -- the spreading of groups of swimming microbes and of reaction fronts. The results from these experiments could help explain how algae blooms form and how diseases spread in moving populations; an understanding of active mixing could also help in the development of “self-assembled” microstructures. All of the research is done with undergraduate students, giving them experiences that play an important role in their development as scientists.Technical AbstractThe experiments in this project study the effects of laminar flows on active impurities that consume energy, resulting in motion relative to the fluid. The active impurities are (a) self-propelled microbes, such as swimming bacteria and algae; and (b) propagating chemical reaction fronts. The flows include vortex chain and vortex array flows, hyperbolic flows in a cross-channel, time-dependent channel flows, and spatially-disordered flows. Previous experiments by the PI’s group have demonstrated that “burning invariant manifolds” and “swimming invariant manifolds” block the motion of active impurities in laminar flows. We will extend these studies to explore transport and pattern formation of active impurities over distances larger than typical flow scales. The experiments will investigate: (1) the effects of laminar mixing on the growth of microbial colonies, both with and without chemo- and phototaxis; (2) the effects of chaotic fluid mixing on biofilm formation; (3) large-scale propagation of reaction fronts and the leading edges of microbial ensembles; (4) chaotic motion of active impurities in flows where passive mixing is non-chaotic; (5) long-range transport of active impurities in laminar flows; and (6) how selection over multiple generations enhances certain swimming protocols in response to the fluid mixing.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.
本项目中的实验探索流体流动对“活性”物质的影响,如游动的生物和移动的反应前沿。流体流动在自然界和技术中无处不在,包括在生物体中;在河流、湖泊和海洋中;在大气和恒星中;在许多工业过程中;甚至在社会中的人的“流动”中。这些实验测试的预测是,流体混合可以同步微生物菌落的生长,类似于海洋中藻类的快速“开花”;流动中的混合模式可以影响表面生物膜的形成;游泳和流体流动的结合可能导致“混乱”的轨迹;流动可以促进--有时甚至抑制--游泳微生物群体和反应前沿的传播。这些实验的结果可以帮助解释藻类水华是如何形成的,以及疾病是如何在流动的种群中传播的;对主动混合的理解也可以帮助开发“自组装”的微结构。所有的研究都是在本科生身上完成的,给他们提供了在他们作为科学家的发展中发挥重要作用的经验。技术摘要本项目中的实验研究了层流对消耗能量的活性杂质的影响,导致相对于流体的运动。活性杂质是(A)自行推进的微生物,如游动的细菌和藻类;以及(B)传播化学反应前沿。这些流动包括涡链和涡阵流动、跨通道中的双曲流动、时间相关的通道流动和空间无序流动。PI小组以前的实验已经证明,“燃烧不变流形”和“游动不变流形”阻碍了层流中活性杂质的运动。我们将扩展这些研究,以探索活性杂质在比典型流动尺度更大的距离上的传输和图案形成。这些实验将研究:(1)层流混合对微生物菌落生长的影响,包括趋化性和趋光性;(2)混沌流体混合对生物膜形成的影响;(3)反应前沿和微生物群前沿的大规模传播;(4)被动混合非混沌流动中活性杂质的混沌运动;(5)层流流中活性杂质的远程传输;以及(6)多代选拔如何改进某些游泳方案以应对液体混合。该奖项反映了NSF的法定使命,并通过使用基金会的智力优势和更广泛的影响审查标准进行评估,被认为值得支持。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Thomas Solomon其他文献
OA-41 Iberdomide, bortezomib, and dexamethasone (IberVd) in transplant-ineligible newly diagnosed multiple myeloma (NDMM): results from the CC-220-MM-001 trial
- DOI:
10.1016/s2152-2650(23)01608-7 - 发表时间:
2023-09-01 - 期刊:
- 影响因子:
- 作者:
Darrell White;Brea Lipe;Mercedes Gironella Mesa;Ruben Niesvizky;Albert Oriol;Anna Sureda Balari;Manisha Bhutani;Cristina Encinas;Abdullah Khan;Michael Amatangelo;Kexin Jin;Thomas Solomon;Kevin Hong;Alpesh Amin;Paulo Maciag;Niels van de Donk;Sagar Lonial - 通讯作者:
Sagar Lonial
Theory and Method in Popular Music Analysis: Text and Meaning
流行音乐分析的理论与方法:文本与意义
- DOI:
- 发表时间:
2012 - 期刊:
- 影响因子:0
- 作者:
Thomas Solomon - 通讯作者:
Thomas Solomon
MM-488 Iberdomide, Bortezomib, and Dexamethasone (IberVd) in Transplant-Ineligible Newly Diagnosed Multiple Myeloma (NDMM): Results From the CC-220-MM-001 Trial
- DOI:
10.1016/s2152-2650(24)01687-2 - 发表时间:
2024-09-01 - 期刊:
- 影响因子:
- 作者:
Darrell White;Brea Lipe;Mercedes Gironella;Ruben Niesvizky;Albert Oriol;Anna Sureda Balari;Manisha Bhutani;Cristina Encinas;Abdullah Khan;Michael Amatangelo;Kexin Jin;Thomas Solomon;Kevin Hong;Alpesh Amin;Paulo Maciag;Niels W.C.J. van de Donk;Sagar Lonial - 通讯作者:
Sagar Lonial
Among the Jasmine Trees: Music and Modernity in Contemporary Syria . By Jonathan Holt Shannon. Middletown: Wesleyan University Press, 2006. xxvi + 252 pp. ISBN 978-0-8195-6798-7
茉莉花树丛中:当代叙利亚的音乐与现代性。
- DOI:
10.1017/s0261143009990183 - 发表时间:
2009 - 期刊:
- 影响因子:0.4
- 作者:
Thomas Solomon - 通讯作者:
Thomas Solomon
OA-55 Iberdomide, Daratumumab, and Dexamethasone (IberDd) in Transplant-Ineligible (TNE) Newly Diagnosed Multiple Myeloma (NDMM): Results From the CC-220-MM-001 Trial
- DOI:
10.1016/s2152-2650(24)01896-2 - 发表时间:
2024-09-01 - 期刊:
- 影响因子:
- 作者:
Anna Sureda Balari;Abdullah Khan;Albert Oriol;Mercedes Gironella Mesa;Faiz Anwer;Cristina Encinas Rodríguez;Brea Lipe;Paula Rodríguez-Otero;Michael Amatangelo;Kexin Jin;Thomas Solomon;Lilia Taningco;Alpesh Amin;Paulo Maciag;Sagar Lonial - 通讯作者:
Sagar Lonial
Thomas Solomon的其他文献
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{{ truncateString('Thomas Solomon', 18)}}的其他基金
RUI: Lagrangian studies of active mixing -- barriers, enhanced transport and collective behavior
RUI:主动混合的拉格朗日研究——障碍、增强的运输和集体行为
- 批准号:
1806355 - 财政年份:2018
- 资助金额:
$ 19.49万 - 项目类别:
Standard Grant
RUI: The effects of three-dimensional fluid flows on front propagation
RUI:三维流体流动对前沿传播的影响
- 批准号:
1361881 - 财政年份:2014
- 资助金额:
$ 19.49万 - 项目类别:
Standard Grant
Workshop: Nonlinear Dynamics and Fluid Instabilities in the 21st Century; Haverford College; near Philadelphis, Pennsylvania; May 19 - 20, 2011
研讨会:21世纪的非线性动力学和流体不稳定性;
- 批准号:
1103121 - 财政年份:2011
- 资助金额:
$ 19.49万 - 项目类别:
Standard Grant
RUI: Reaction Fronts in Fluid Flows -- Pinning, Lobes and Flights
RUI:流体流动中的反应前沿——钉扎、波瓣和飞行
- 批准号:
1004744 - 财政年份:2010
- 资助金额:
$ 19.49万 - 项目类别:
Standard Grant
RUI: Fronts and Patterns in Advection-Reaction-Diffusion Systems
RUI:平流反应扩散系统的前沿和模式
- 批准号:
0703635 - 财政年份:2007
- 资助金额:
$ 19.49万 - 项目类别:
Standard Grant
RUI: Pattern Formation in Reaction-Advection-Diffusion Systems with Lagrangian Chaos
RUI:拉格朗日混沌反应-平流-扩散系统中的模式形成
- 批准号:
0404961 - 财政年份:2004
- 资助金额:
$ 19.49万 - 项目类别:
Standard Grant
RUI: Lagrangian Chaos: Phase Separation, Coalescence and Aggregation
RUI:拉格朗日混沌:相分离、合并和聚集
- 批准号:
0071771 - 财政年份:2000
- 资助金额:
$ 19.49万 - 项目类别:
Standard Grant
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