Conference: 2023 Plant Proteolysis Gordon Research Conference

蛋白质水解，即蛋白质或多肽分解为氨基酸，对于去除不需要或受损的蛋白质和调节细胞过程（如新陈代谢）至关重要。这次戈登研究会议（GRC）将汇集快速增长的国际研究人员，专注于植物蛋白水解，包括高度多样化的研究生，博士后科学家和新的研究人员。互动、非正式的环境将导致新的联系和合作的发展。因此，本次会议预期的长期影响是加速跨学科的植物蛋白水解研究及其对农业和生物技术的影响，并促进公共和私营部门研究人员之间的合作。蛋白酶以各种方式识别其底物，包括翻译后修饰和条件降解，使细胞能够快速重塑蛋白质组并适应不利条件。这个新的戈登研究会议（GRC）将汇集研究植物蛋白水解的各个方面的研究人员，涵盖广泛的学科，包括细胞和分子生物学，化学和生物化学，成像，物理学和系统生物学，以产生新的研究途径，并为一些社会挑战提供解决方案。邀请来自非植物领域的研究人员提供附加价值，以加速工具的开发和应用，并了解蛋白质水解系统的进化多样化。新的GRC会议将有助于扩大分散群体的科学家群体，这些群体在揭示蛋白质水解在植物生物学中的作用方面有着共同的目标。NSF对这一GRC的支持将吸引和扩大早期职业科学家的参与，包括urm进入这一新兴领域，从而加强和加速植物蛋白水解的未来发现。该奖项反映了美国国家科学基金会的法定使命，并通过使用基金会的知识价值和更广泛的影响审查标准进行评估，被认为值得支持。

Proteolysis, the breakdown of proteins or peptides to amino acids, is critical for removal of unwanted or damaged proteins and regulation of cellular processes such as metabolism. This Gordon Research Conference (GRC) will bring together the rapidly growing international community of researchers focused on plant proteolysis including a highly diverse group of graduate students, postdoctoral scientists and new investigators. The interactive, informal environment will lead to development of new contacts and collaborations. The anticipated long-term impact of this conference is therefore to accelerate plant proteolysis research across disciplines and its impact of agriculture and biotechnology, and catalyze collaboration between researchers in the public and private sectors.Proteases recognize their substrates in various ways, including post-translational modifications and conditional degrons that allow the cell to rapidly reshape the proteome and acclimate to adverse conditions. This new Gordon Research Conference (GRC) will bring together researchers studying all aspects of plant proteolysis and covering a wide range of disciplines, including cell and molecular biology, chemistry and biochemistry, imaging, physics and systems biology, to generate new research avenues and provide solutions to some of society’s challenges. Added value will be provided by invited researchers from non-plant fields to accelerate tool development and application, and to understand evolutionary diversification of proteolytic systems. The new GRC meeting will help grow the community of scientists in dispersed communities that share common goals in unraveling the role of proteolysis in plant biology. NSF support for this GRC will attract and broaden participation of early career scientists, including URMs into this emerging field, and thereby strengthening and accelerating future discoveries in Plant Proteolysis.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.