MRI: Track 1 Development of a Combined Optical and Magnetic Resonance Spectroscopy System

MRI：光学和磁共振组合光谱系统的轨道 1 开发

• 批准号: 2320520
• 负责人: Ashok Ajoy
• 金额: $ 87万
• 依托单位: University of California-Berkeley
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-09-01 至 2026-08-31
• 项目状态: 未结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2320520&HistoricalAwards=false
• 关键词: MRI; Track; Development; Combined; Optical

This award is jointly supported by the Major Research Instrumentation (MRI), the Chemistry Research Instrumentation, and Chemical Measurement and Imaging (CMI) programs. The University of California at Berkeley is developing an instrument which incorporates nuclear magnetic resonance (NMR), electron paramagnetic resonance (EPR) and an optical fluorescence spectrometer to support the research of Professor Ashok Ajoy along with colleague Jeffery Reimer. This instrument facilitates research in the areas of materials science, quantum information science, energy storage, and catalysis. This development project enables the simultaneous manipulation of electronic and nuclear spins of proteins, materials, and molecular systems employing the ability to rapidly transport the sample from low to high or high to low magnetic fields at cryogenic temperatures. By combining the three spectroscopic techniques, the instrument enables users to perform cutting-edge dynamic nuclear polarization (DNP) techniques which significantly improve the sensitivity of magnetic resonance experiments for the thorough characterization of the properties of molecular systems. Students and trainees from the undergraduate to postdoctoral level are involved in the development and testing of the instrument. The completed instrument benefits a wide array of research groups and undergraduate students, including those from diverse backgrounds and from a predominately undergraduate institution in the Bay Area, San Jose State University. Multiple investigators from additional universities and Lawrence Berkeley National Laboratory also benefit from this resource.This award is aimed at enhancing research and education at all levels. The instrument enables the development of an optical dynamic nuclear polarization (DNP) NMR system to study metal-organic frameworks. The instrumentation is also used to probe electrons optically and via spin resonance to uncover the role of interactions with their nuclear environment and thereby enable the study of molecular systems for applications in quantum information science. Additionally, the instrument enables the investigation of the chemical surface structure of bulk and nanoscale materials for enhanced quantum sensors and the development of a sub-micron scale NMR in-situ chemical probe within microdroplets using nuclear spin in nanodiamonds as quantum sensors. The instrument also allows the unique ability to simultaneously probe EPR active systems and perform in-situ DNP measurements of light-harvesting complexes within photosystems. Furthermore, by using the three modalities, this instrument aids in understanding the interplay between the electron g-factor and the resulting optically pumped NMR spectra in bulk or heterostructured semiconductors.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

该奖项由重大研究仪器(MRI)、化学研究仪器以及化学测量和成像(CMI)计划联合支持。加州大学伯克利分校正在开发一种集核磁共振(核磁共振)、电子顺磁共振(EPR)和光学荧光光谱仪于一体的仪器，以支持阿肖克·阿霍伊教授和同事杰弗里·雷默的研究。该仪器促进了材料科学、量子信息科学、能量存储和催化等领域的研究。这一开发项目能够同时操纵蛋白质、材料和分子系统的电子自旋和核自旋，利用在低温下快速将样品从低磁场传输到高磁场或从高磁场传输到低磁场的能力。通过结合三种光谱技术，该仪器使用户能够执行尖端的动态核极化(DNP)技术，从而显著提高磁共振实验的灵敏度，以彻底表征分子体系的性质。从本科生到博士后水平的学生和实习生都参与了仪器的开发和测试。完成的仪器使广泛的研究小组和本科生受益，包括来自不同背景的人，以及来自旧金山湾区以本科生为主的机构圣何塞州立大学。来自更多大学和劳伦斯伯克利国家实验室的多名研究人员也受益于这一资源。该奖项旨在加强各级研究和教育。该仪器能够开发光学动态核极化(DNP)核磁共振系统来研究金属-有机骨架。该仪器还用于光学和通过自旋共振探测电子，以揭示与其核环境相互作用的作用，从而使研究分子系统在量子信息科学中的应用成为可能。此外，该仪器还可以研究用于增强型量子传感器的块状和纳米材料的化学表面结构，并利用纳米钻石中的核自旋作为量子传感器，在微滴中开发亚微米级的核磁共振原位化学探针。该仪器还允许同时探测EPR活性系统并对光系统内的捕光复合体进行原位DNP测量的独特能力。此外，通过使用这三种模式，该仪器有助于理解块状或异质结构半导体中电子g因子和由此产生的光泵浦核磁共振谱之间的相互作用。这一奖项反映了NSF的法定使命，并通过使用基金会的智力优势和更广泛的影响审查标准进行评估，被认为值得支持。