Equipment: MRI: Track 2 Acquisition of an Automated High-Throughput System for Combinatorial Design and Development of Complex Polymer Systems
设备: MRI:轨道 2 获取用于复杂聚合物系统的组合设计和开发的自动化高通量系统
基本信息
- 批准号:2320276
- 负责人:
- 金额:$ 359.6万
- 依托单位:
- 依托单位国家:美国
- 项目类别:Standard Grant
- 财政年份:2023
- 资助国家:美国
- 起止时间:2023-09-01 至 2026-08-31
- 项目状态:未结题
- 来源:
- 关键词:
项目摘要
This Major Research Instrumentation (MRI) award supports the acquisition of an automated system for high-throughput formulation and characterization of complex polymer materials at the University of Illinois at Urbana-Champaign. This state-of-the-art system integrates component dispensing, mixing, and processing with high-throughput rheological, optical, and thermal characterization of materials. The automated system will enable AI-guided, closed-loop approaches for the design, discovery, and development of new polymeric materials for energy-efficient manufacturing, multi-functional polymers, and new sustainable thermoplastics and thermosets. The automated system is designed to accommodate a variety of research workflows and will include in-line characterization equipment including a rheometer and a differential scanning calorimeter (DSC). Automation will enable data-driven discovery of new materials by drastically increasing the number of samples created and analyzed (up to 50x increase) and the data usability (up to 100x increase) by systematically generating annotated datasets. Production of well-curated data will further increase the impact of the research by promoting the publishing of data to open access national repositories. The instrument will promote synergistic connections between Illinois and external academic and industrial partners while leveraging existing institutes and materials research efforts on campus. Overall, the high-throughput system will fundamentally change how advanced materials are designed and developed by enabling data-driven, closed-loop design and characterization approaches for complex formulations of polymeric materials. This research is aimed at advancing the rate of innovation in materials discovery by enabling data-driven approaches in polymer science. The proposed instrumentation will support the training of students and researchers to include high-throughput, robotic, and data-driven methodologies, which is critical for modern industry and advanced materials manufacturing. Automated instrumentation fundamentally changes how materials research is conducted by enabling high-throughput discovery campaigns, enhanced repeatability of experimental measurements, and improved accuracy of data. Automated characterization will further facilitate the use of artificial intelligence-based methods for materials discovery by greatly expanding the chemical and physical properties space that can be experimentally explored. This research will enable the rapid discovery and development of high-performance polymer materials to address the most pressing challenges in energy, sustainability, and advanced manufacturing. This instrumentation will bring unique capabilities by accelerating fundamental and applied polymer research, while further preparing the next-generation work force for future careers in materials science, chemical engineering, aerospace, data science, and related disciplines that rely on polymer materials. The instrument will support educational outreach efforts and undergraduate research laboratories while further engaging with students in the Worldwide Youth in Science and Engineering (WYSE) camps and the Beckman Institute Open House activities.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.
该重大研究仪器(MRI)奖支持伊利诺伊大学厄巴纳-香槟分校收购用于高通量配制和表征复杂聚合物材料的自动化系统。这一最先进的系统将成分分配、混合和加工与材料的高通量流变、光学和热表征集成在一起。自动化系统将使人工智能指导的闭环方法能够设计、发现和开发用于节能制造的新型聚合物材料、多功能聚合物以及新型可持续热塑性塑料和热固性材料。该自动化系统旨在适应各种研究工作流程,并将包括在线表征设备,包括流变仪和差示扫描量热仪(DSC)。自动化将通过系统地生成带注释的数据集,大幅增加创建和分析的样本数量(最多增加50倍)和数据可用性(最多增加100倍),从而实现数据驱动的新材料发现。编制精心编排的数据将通过促进向开放获取的国家储存库发布数据,进一步增加研究的影响。该工具将促进伊利诺伊州与外部学术和工业合作伙伴之间的协同联系,同时利用校园内现有的研究所和材料研究努力。总体而言,高通量系统将从根本上改变先进材料的设计和开发方式,为复杂的聚合物材料配方提供数据驱动的闭环设计和表征方法。这项研究的目的是通过在聚合物科学中实现数据驱动的方法来提高材料发现的创新速度。拟议的仪器将支持对学生和研究人员的培训,以包括高通量、机器人和数据驱动的方法,这对现代工业和先进材料制造至关重要。自动化仪器从根本上改变了材料研究的方式,实现了高通量的发现活动,增强了实验测量的重复性,并提高了数据的准确性。自动化表征将进一步促进基于人工智能的材料发现方法的使用,因为它大大扩展了可以进行实验探索的化学和物理性质空间。这项研究将使高性能聚合物材料的快速发现和开发能够应对能源、可持续发展和先进制造方面最紧迫的挑战。这种仪器将带来独特的能力,加速基础和应用聚合物研究,同时进一步为下一代劳动力在材料科学、化学工程、航空航天、数据科学以及依赖聚合物材料的相关学科的未来职业生涯做好准备。该工具将支持教育推广工作和本科生研究实验室,同时进一步与世界科学与工程青年(Wyse)夏令营和Beckman Institute Open House活动的学生接触。该奖项反映了NSF的法定使命,并通过使用基金会的智力优势和更广泛的影响审查标准进行评估,被认为值得支持。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Charles Schroeder其他文献
STROKE AND MYASTHENIA GRAVIS LEAD TO CRISIS IN THE ELDERLY
- DOI:
10.1016/j.chest.2019.08.1207 - 发表时间:
2019-10-01 - 期刊:
- 影响因子:
- 作者:
Nick Meyerkord;Yunna Sinskey;Shashank Varakantam;Sana Khan;Charles Schroeder;Nemer Dabage-Forzoli - 通讯作者:
Nemer Dabage-Forzoli
Dose and location-dependent effects of transcranial magnetic stimulation in nonhuman primates
- DOI:
10.1016/j.brs.2023.01.513 - 发表时间:
2023-01-01 - 期刊:
- 影响因子:
- 作者:
Nipun Perera;Sina Shirinpour;Ivan Alekseichuk;Miles Wischnewski;Gary Linn;Charles Schroeder;Arnaud Falchier;Alexander Opitz - 通讯作者:
Alexander Opitz
Intracranial electric field measurements during TES. Identifying determinant factors of the electric field distribution
- DOI:
10.1016/j.brs.2017.04.081 - 发表时间:
2017-07-01 - 期刊:
- 影响因子:
- 作者:
Alexander Opitz;Erin Yeagle;Axel Thielscher;Charles Schroeder;Ashesh Mehta;Michael P. Milham - 通讯作者:
Michael P. Milham
Layer-specific effects of electrical stimulation on local field potentials in the primary visual cortex of monkeys
电刺激对猴初级视觉皮层局部场电位的层特异性效应
- DOI:
10.1016/j.brs.2024.12.1091 - 发表时间:
2025-01-01 - 期刊:
- 影响因子:8.400
- 作者:
Sangjun Lee;Ivan Alekseichuk;Zhihe Zhao;Charles Schroeder;Arnaud Falchier;Alexander Opitz - 通讯作者:
Alexander Opitz
Engineering Zinc Finger Proteins using Accessory Binding Modules
- DOI:
10.1016/j.bpj.2011.11.433 - 发表时间:
2012-01-31 - 期刊:
- 影响因子:
- 作者:
Kathryn Trenshaw;Younghoon Kim;Nathan Yee;Peiyi Wang;Charles Schroeder - 通讯作者:
Charles Schroeder
Charles Schroeder的其他文献
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{{ truncateString('Charles Schroeder', 18)}}的其他基金
Collaborative Research: Dynamics and Stability of Multi-Component Lipid Vesicles in Flow
合作研究:多组分脂质囊泡流动的动力学和稳定性
- 批准号:
2147560 - 财政年份:2022
- 资助金额:
$ 359.6万 - 项目类别:
Standard Grant
Collaborative Research: Micromechanics of Meniscus-bound Particle Clusters
合作研究:弯月面束缚粒子簇的微观力学
- 批准号:
2030537 - 财政年份:2020
- 资助金额:
$ 359.6万 - 项目类别:
Standard Grant
Direct Observation of Vesicle Dynamics, Collision, and Adhesion
直接观察囊泡动力学、碰撞和粘附
- 批准号:
1704668 - 财政年份:2017
- 资助金额:
$ 359.6万 - 项目类别:
Standard Grant
Collaborative Research: Dynamics of Circular Macromolecules (DNA): From Single Molecules to Highly Entangled States
合作研究:圆形大分子(DNA)动力学:从单分子到高度纠缠态
- 批准号:
1604038 - 财政年份:2016
- 资助金额:
$ 359.6万 - 项目类别:
Standard Grant
WORKSHOP: Neurobiology of Cognition: Circuits, dynamics, action and perception GRC & GRS
研讨会:认知神经生物学:回路、动力学、动作和感知 GRC
- 批准号:
1441810 - 财政年份:2014
- 资助金额:
$ 359.6万 - 项目类别:
Standard Grant
CAREER: Molecular Rheology of Architecturally Complex Polymers
职业:结构复杂聚合物的分子流变学
- 批准号:
1254340 - 财政年份:2013
- 资助金额:
$ 359.6万 - 项目类别:
Standard Grant
Multisensory Form Processing in Extrastriate Visual Cortex
纹状体视觉皮层的多感官形式处理
- 批准号:
0519410 - 财政年份:2005
- 资助金额:
$ 359.6万 - 项目类别:
Continuing Grant
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