ORS Musculoskeletal Biology Workshop at Zermatt

采尔马特 ORS 肌肉骨骼生物学研讨会

• 批准号: 10753967
• 负责人: ALEXANDER G ROBLING
• 金额: $ 1.5万
• 依托单位: INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-07-01 至 2028-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10753967
• 关键词: Address; Award; Basic Science; Biology; Biomechanics; Bone Diseases; Cartilage Diseases; Cells; Cities; Clinical; Clinical Investigator; Communities; Degenerative polyarthritis; Development; Disease; Educational workshop; Electronic Mail; Engineering; Faculty; Feedback; Goals; Idaho; Image; Interdisciplinary Communication; Link; Location; Molecular; Molecular Target; Musculoskeletal; Musculoskeletal Diseases; Myopathy; Orthopedics; Osteoclasts; Pathogenesis; Physicians; Prevention; Problem Solving; Process; Public Health; Request for Applications; Research; Research Personnel; Resort; Scientific Advances and Accomplishments; Scientist; Senior Scientist; Societies; Sodium Chloride; Students; Therapeutic; Time; Tissues; Utah; Work; bone; career development; clinical practice; improved; insight; interdisciplinary collaboration; meetings; multidisciplinary; public health relevance; response; skeletal disorder; skeletal stem cell; student training; symposium; tool; web site

Description This application requests support for the 50th annual meeting of the ORS Musculoskeletal Biology Workshop, which had been held at Sun Valley, Idaho, for the past 20+ years. In 2022 the Workshop moved to the Utah Rockies, just outside Salt Lake City. The 2023 workshop will be held in Midland, Utah at the Zermatt Resort, from July 21-25, 2023. The Workshop was moved to the new location in response to feedback from attendees over the past several years, who expressed a desire to have the meeting at a venue that was less expensive and easier to get to. We have achieved both of those improvements with the new location. The conference itself will maintain the same spirit it has enjoyed for several decades: it emphasizes active participation of junior faculty and students; promotes interdisciplinary communication; and is unusual in that discussion time equals or exceeds time allotted for formal presentation. The goals of the Workshop are to (1) work toward a multidisciplinary basic and clinical synthesis of molecular, tissue and biomechanical processes in musculoskeletal tissues that help us to understand the pathogenesis of bone, muscle, and cartilage disease as well as its prevention and treatment; (2) apply basic science concepts to clinical problems; develop a dialogue between basic and clinical investigators that leads to interdisciplinary collaboration; (3) identify significant problems in musculoskeletal disease, and identify experimental approaches that provide solutions to them and (4) provide a forum for student training and the opportunity in a small group setting for junior scientists to talk with more senior scientists. A partnership between the Workshop and the Orthopaedic Research Society (ORS) provides maximum visibility through broadcast emails and links on the ORS website. This year we continue our newly instituted focus on problem solving, with the theme for the Workshop being “Musculoskeletal cells: identity, targeting, stimulation, and manipulation for therapeutic gain.” Six sessions address relevant and significant current problems, including current challenges with rare skeletal disease, recent breakthroughs in our understanding of the biology of osteoarthritis, progress in bone-targeting molecular tools for delivery of therapeutics, new insights into osteoclast origin and fate, advances in skeletal stem cells, and the intersection of mechanobiology and imaging. A notable feature of this Workshop is that it is becoming a truly musculoskeletal workshop, considering problems of musculoskeletal conditions beyond bone, though the major focus remains bone. Opportunities are provided for junior investigators to interact with more senior investigators. Two Career Development sessions specifically geared toward young investigators will be conducted. Ten ASBMR/Frost Young Investigator Awardees will present their work from the podium. Ten or more Jee Young Investigator Awards will also be distributed to increase young investigator attendance and participation.

描述 本申请请求支持第50届ORS肌肉骨骼生物学研讨会年会， 在过去的20多年里，它一直在爱达荷州的太阳谷举行。2022年，工作室搬到了犹他州。 落基山脉，就在湖城外。2023年研讨会将在犹他州的米德兰采尔马特度假村举行， 2023年7月21日至25日。根据与会者的反馈意见，讲习班移至新地点 在过去几年中，世卫组织表示希望在一个费用较低的地点举行会议， 也更容易接近我们在新的地点实现了这两项改进。会议 它本身将保持几十年来一直享有的精神：它强调年轻人的积极参与 教师和学生;促进跨学科的沟通;是不寻常的，讨论时间等于 或超过规定的正式陈述时间。研讨会的目标是（1）努力实现 分子、组织和生物力学过程的多学科基础和临床综合， 肌肉骨骼组织，帮助我们了解骨骼，肌肉和软骨疾病的发病机制， 及其预防和治疗;（2）将基本科学概念应用于临床问题;开展对话 基础和临床研究者之间的合作，导致跨学科的合作;（3）确定重要的 肌肉骨骼疾病的问题，并确定实验方法，提供解决方案， (4)为学生培训提供一个论坛，并为初级科学家提供小组讨论的机会 更资深的科学家讲习班和矫形外科研究学会之间的伙伴关系 (ORS)通过广播电子邮件和ORS网站上的链接提供最大的可见度。今年我们 继续我们新制定的重点是解决问题，讲习班的主题是 “肌肉骨骼细胞：身份，靶向，刺激和操纵治疗增益。六中 解决当前的相关和重大问题，包括罕见骨骼疾病的当前挑战， 骨关节炎生物学的最新突破，骨靶向分子治疗的进展， 治疗药物的递送工具，破骨细胞起源和命运的新见解，骨骼干细胞的进展， 以及机械生物学和成像的交叉点。这次研讨会的一个显著特点是， 一个真正的肌肉骨骼研讨会，考虑骨骼以外的肌肉骨骼问题，虽然 主要焦点仍然是骨。初级调查员有机会与更高级的调查员进行互动 investigators.两个专门针对年轻调查员的职业发展课程将在 进行。十名ASBMR/弗罗斯特青年研究员获奖者将在讲台上展示他们的工作。十个或 还将分发更多的Jee Young Investigator Awards，以增加年轻调查员的出勤率， 参与的