ORS Musculoskeletal Biology Workshop at Zermatt

采尔马特 ORS 肌肉骨骼生物学研讨会

• 批准号: 10753967
• 负责人: ALEXANDER G ROBLING
• 金额: $ 1.5万
• 依托单位: INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-07-01 至 2028-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10753967
• 关键词: Address; Award; Basic Science; Biology; Biomechanics; Bone Diseases; Cartilage Diseases; Cells; Cities; Clinical; Clinical Investigator; Communities; Degenerative polyarthritis; Development; Disease; Educational workshop; Electronic Mail; Engineering; Faculty; Feedback; Goals; Idaho; Image; Interdisciplinary Communication; Link; Location; Molecular; Molecular Target; Musculoskeletal; Musculoskeletal Diseases; Myopathy; Orthopedics; Osteoclasts; Pathogenesis; Physicians; Prevention; Problem Solving; Process; Public Health; Request for Applications; Research; Research Personnel; Resort; Scientific Advances and Accomplishments; Scientist; Senior Scientist; Societies; Sodium Chloride; Students; Therapeutic; Time; Tissues; Utah; Work; bone; career development; clinical practice; improved; insight; interdisciplinary collaboration; meetings; multidisciplinary; public health relevance; response; skeletal disorder; skeletal stem cell; student training; symposium; tool; web site

Description This application requests support for the 50th annual meeting of the ORS Musculoskeletal Biology Workshop, which had been held at Sun Valley, Idaho, for the past 20+ years. In 2022 the Workshop moved to the Utah Rockies, just outside Salt Lake City. The 2023 workshop will be held in Midland, Utah at the Zermatt Resort, from July 21-25, 2023. The Workshop was moved to the new location in response to feedback from attendees over the past several years, who expressed a desire to have the meeting at a venue that was less expensive and easier to get to. We have achieved both of those improvements with the new location. The conference itself will maintain the same spirit it has enjoyed for several decades: it emphasizes active participation of junior faculty and students; promotes interdisciplinary communication; and is unusual in that discussion time equals or exceeds time allotted for formal presentation. The goals of the Workshop are to (1) work toward a multidisciplinary basic and clinical synthesis of molecular, tissue and biomechanical processes in musculoskeletal tissues that help us to understand the pathogenesis of bone, muscle, and cartilage disease as well as its prevention and treatment; (2) apply basic science concepts to clinical problems; develop a dialogue between basic and clinical investigators that leads to interdisciplinary collaboration; (3) identify significant problems in musculoskeletal disease, and identify experimental approaches that provide solutions to them and (4) provide a forum for student training and the opportunity in a small group setting for junior scientists to talk with more senior scientists. A partnership between the Workshop and the Orthopaedic Research Society (ORS) provides maximum visibility through broadcast emails and links on the ORS website. This year we continue our newly instituted focus on problem solving, with the theme for the Workshop being “Musculoskeletal cells: identity, targeting, stimulation, and manipulation for therapeutic gain.” Six sessions address relevant and significant current problems, including current challenges with rare skeletal disease, recent breakthroughs in our understanding of the biology of osteoarthritis, progress in bone-targeting molecular tools for delivery of therapeutics, new insights into osteoclast origin and fate, advances in skeletal stem cells, and the intersection of mechanobiology and imaging. A notable feature of this Workshop is that it is becoming a truly musculoskeletal workshop, considering problems of musculoskeletal conditions beyond bone, though the major focus remains bone. Opportunities are provided for junior investigators to interact with more senior investigators. Two Career Development sessions specifically geared toward young investigators will be conducted. Ten ASBMR/Frost Young Investigator Awardees will present their work from the podium. Ten or more Jee Young Investigator Awards will also be distributed to increase young investigator attendance and participation.

描述 该申请要求支持ORS肌肉骨骼生物学研讨会的第50届年度会议， 在过去的20多年中，它在爱达荷州的太阳谷举行。 2022年，研讨会搬到了犹他州 落基山脉，就在盐湖城外。 2023年的研讨会将在犹他州米德兰举行， 从2023年7月21日至25日开始。研讨会被转移到新地点，以回应与会者的反馈 在过去的几年中，他们表示希望在价格较低的场地举行会议 更容易到达。我们已经通过新地点实现了这两个改进。会议 本身将保持与几十年来所享有的同样的精神：它强调了初中的积极参与 教师和学生；促进跨学科的交流；在讨论时间等于 或超过分配的时间进行正式演示。研讨会的目标是（1）朝着一个 分子，组织和生物力学过程的多学科基本和临床合成 肌肉骨骼组织有助于我们理解骨，肌肉和软骨疾病的发病机理 以及预防和治疗； （2）将基本科学概念应用于临床问题；建立对话 在导致跨学科合作的基础研究人员和临床研究人员之间； （3）确定重要的 肌肉骨骼疾病的问题，并确定为它们提供解决方案的实验方法， （4）为学生培训提供了一个论坛，并在小组环境中提供了一个初级科学家进行交谈的机会 与更多的高级科学家。研讨会与骨科研究协会之间的伙伴关系 （ORS）通过ORS网站上的广播电子邮件和链接提供最大的可见性。今年我们 继续我们新成立的关注问题解决问题，讲习班的主题是 “肌肉骨骼细胞：认同，靶向，刺激和操纵治疗性增益。”六次会议 解决相关和重大的当前问题，包括目前遇到罕见骨骼疾病的挑战， 在我们对骨关节炎的生物学的理解中，最近的突破，靶向骨头的进展 提供治疗的工具，对破骨细胞起源和命运的新见解，骨骼干细胞的进步， 以及机械生物学和成像的交集。该研讨会的一个显着特征是它正在变得 一个真正的肌肉骨骼研讨会，考虑到骨骼以外的肌肉骨骼状况的问题 主要重点仍然是骨头。为初级调查人员提供了机会，可以与更多的高级互动 调查人员。专门针对年轻调查人员的两个职业发展会议将是 实施。十名ASBMR/Frost的年轻调查员获奖者将从讲台上介绍他们的作品。十或 还将分发更多JEE年轻调查员奖，以增加年轻的研究者出勤率和 参与。