ORS Musculoskeletal Biology Workshop at Snowbird

描述 本申请请求支持第 49 届 ORS 肌肉骨骼年会 生物学研讨会已在爱达荷州太阳谷举办了 20 年。 2021年 研讨会将于 7 月 24 日至 28 日在犹他州斯诺伯德举行。车间搬迁至 根据过去几年与会者的反馈，新地点 表示希望在一个更便宜且更容易到达的地点举行会议。 我们通过新地点实现了这两项改进。会议本身将 保持了几十年来的相同精神：强调积极参与 初级教师和学生；促进跨学科交流；不寻常之处在于 讨论时间等于或超过分配给正式演示的时间。的目标 研讨会的目标是 (1) 致力于分子的多学科基础和临床综合， 肌肉骨骼组织中的组织和生物力学过程，帮助我们了解 骨、肌肉、软骨疾病的发病机制及其预防和治疗； (2) 将基本科学概念应用于临床问题；在基础和基础之间建立对话 导致跨学科合作的临床研究人员； (3) 识别重大问题 肌肉骨骼疾病，并确定为其提供解决方案的实验方法 (4) 为学生培训提供论坛，并为初级学生提供小组环境的机会 科学家与更资深的科学家交谈。研讨会与 骨科研究协会 (ORS) 通过广播电子邮件和 ORS 网站上的链接。今年我们继续将新的重点放在解决问题上， 研讨会的主题是“肌肉骨骼免疫学和 机械转导：从干细胞到衰老细胞的生物学和疾病。”六场分会场致辞 当前相关且重要的问题，包括下一代肌肉骨骼疗法 专注于 senolytics 和自体/自体方法、肌肉骨骼成像 组织、骨免疫学和机械传导，以及骨细胞专题会议 生物学。为初级研究人员提供与更高级研究人员互动的机会 调查人员。专门针对年轻研究者的职业发展研讨会 将进行。九名 ASBMR/Frost 青年研究者奖获得者将展示他们的工作 讲台上。十名 Jee Young 研究员奖获得者，以及最多五名额外的 Jee 奖 将介绍代表性不足的少数群体。 演出现场 犹他州雪鸟 主要人员 名称 组织在项目中的角色 Robling, Alexander G. 印第安纳大学研讨会联合主任，PI Bellido，阿肯色州特雷西塔大学研讨会联合主任，Co-I

Description This application requests support for the 49th annual meeting of the ORS Musculoskeletal Biology Workshop, which has been held at Sun Valley, Idaho, for the past 20+ years. The 2021 Workshop will be held in Snowbird, Utah, from July 24-28. The Workshop was moved to the new location in response to feedback from attendees over the past several years, who expressed a desire to have the meeting at a venue that was less expensive and easier to get to. We have achieved both of those improvements with the new location. The conference itself will maintain the same spirit it has enjoyed for several decades: it emphasizes active participation of junior faculty and students; promotes interdisciplinary communication; and is unusual in that discussion time equals or exceeds time allotted for formal presentation. The goals of the Workshop are to (1) work toward a multidisciplinary basic and clinical synthesis of molecular, tissue and biomechanical processes in musculoskeletal tissues that help us to understand the pathogenesis of bone, muscle, and cartilage disease as well as its prevention and treatment; (2) apply basic science concepts to clinical problems; develop a dialogue between basic and clinical investigators that leads to interdisciplinary collaboration; (3) identify significant problems in musculoskeletal disease, and identify experimental approaches that provide solutions to them and (4) provide a forum for student training and the opportunity in a small group setting for junior scientists to talk with more senior scientists. A partnership between the Workshop and the Orthopaedic Research Society (ORS) provides maximum visibility through broadcast emails and links on the ORS website. This year we continue our newly-instituted focus on problem solving, with the theme for the Workshop being “Musculoskeletal immunology and mechanotransduction: biology and disease from stem to senescent cells.” Six sessions address relevant and significant current problems, including next-generation musculoskeletal therapies focusing on senolytics and autologous/autogenous approaches, imaging of musculoskeletal tissues, osteoimmunology and mechanotransduction, and a focused session on osteocyte biology. Opportunities are provided for junior investigators to interact with more senior investigators. A Career Development Workshop specifically geared toward young investigators will be conducted. Nine ASBMR/Frost Young Investigator Awardees will present their work from the podium. Ten Jee Young Investigator Awardees, and up to five additional Jee Awards for under-represented minorities will be presented. Performance Site Snowbird, Utah Key Personnel Name Organization Role on Project Robling, Alexander G. Indiana University Workshop Co-Director, PI Bellido, Teresita University of Arkansas Workshop Co-Director, Co-I