The role of indoor dust in modulating indoor air chemistry: assessing air-dust heterogeneous transformations and human exposures

室内灰尘在调节室内空气化学方面的作用：评估空气-灰尘异质转化和人体暴露

• 批准号: 2341756
• 负责人: Jenna Ditto
• 金额: $ 45.3万
• 依托单位: Washington University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2024
• 资助国家: 美国
• 起止时间: 2024-03-01 至 2027-02-28
• 项目状态: 未结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2341756&HistoricalAwards=false
• 关键词: role; indoor; dust; modulating; air

This project is focused on characterizing indoor air chemistry that results from the interactions of organic compounds with airborne dust. This work will advance the understanding of indoor dust chemistry, especially in homes susceptible to higher pollutant concentrations from outside source emissions that infiltrate indoors. The results are expected to lead to a better understanding of individual compounds or compound groups in indoor air that pose significant human health risk.Experiments will be conducted to systematically characterize the interactions of gas- and particle-phase organic compounds with indoor dust, including their partitioning and subsequent heterogeneous chemistry. The objectives of this project are to: (1) Characterize the chemical transformation pathways and resulting products from target dust-bound precursors from within complex mixtures of outdoor pollutants (from sources such as motor vehicle, biomass burning, and cooking) that infiltrate the home and become exposed to indoor reactive gases (e.g., ozone, nitrogen oxides, hydroxyl radicals); (2) Identify novel chemical reaction products in lab-generated and genuine complex mixtures of fresh and aged indoor dust using non-targeted mass spectrometry approaches; and (3) Determine the oxidative potential and exposure risks of fresh and aged dust-bound and re-volatilized product mixtures.The chemical composition and exposure risk evaluations of the indoor air studied will be disseminated to the public via an interactive web tool. A series of workshops will be organized for middle school students and their teachers in collaboration with the Institute for School Partnership at Washington University in St. Louis. The project will support students from Lincoln University, a historically Black institution in Jefferson City, MO, to perform laboratory research each summer throughout the project.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

这个项目的重点是描述由有机化合物与空气中的粉尘相互作用产生的室内空气化学。这项工作将促进对室内粉尘化学的理解，特别是在容易受到渗入室内的外源排放的较高污染物浓度影响的家庭中。这些结果有望更好地了解室内空气中对人体健康构成重大风险的单个化合物或化合物组。将进行实验，系统地表征气相和颗粒相有机化合物与室内粉尘的相互作用，包括它们的分配和随后的非均相化学。该项目的目标是：(1)表征来自室外污染物(来自机动车、生物质燃烧和烹饪等来源)的复杂混合物中的目标粉尘结合前体的化学转化途径和结果，这些污染物渗入家庭并暴露在室内反应气体(例如臭氧、氮氧化物、羟基自由基)中；(2)使用非靶向质谱学方法识别实验室产生的和真正的新鲜和陈年室内粉尘的复杂混合物中的新的化学反应产物；以及(3)确定新鲜和陈年的尘埃和再挥发产品混合物的氧化潜力和暴露风险，研究的室内空气的化学成分和暴露风险评估将通过互动网络工具向公众发布。将与圣路易斯华盛顿大学学校伙伴关系研究所合作，为中学生及其教师举办一系列讲习班。该项目将支持林肯大学的学生在整个项目中每年夏天进行实验室研究。林肯大学是密苏里州杰斐逊市的一所历史悠久的黑人院校。该奖项反映了NSF的法定使命，并通过使用基金会的智力优势和更广泛的影响审查标准进行评估，被认为值得支持。