The role of indoor dust in modulating indoor air chemistry: assessing air-dust heterogeneous transformations and human exposures

室内灰尘在调节室内空气化学方面的作用：评估空气-灰尘异质转化和人体暴露

• 批准号: 2341756
• 负责人: Jenna Ditto
• 金额: $ 45.3万
• 依托单位: Washington University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2024
• 资助国家: 美国
• 起止时间: 2024-03-01 至 2027-02-28
• 项目状态: 未结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2341756&HistoricalAwards=false
• 关键词: role; indoor; dust; modulating; air

This project is focused on characterizing indoor air chemistry that results from the interactions of organic compounds with airborne dust. This work will advance the understanding of indoor dust chemistry, especially in homes susceptible to higher pollutant concentrations from outside source emissions that infiltrate indoors. The results are expected to lead to a better understanding of individual compounds or compound groups in indoor air that pose significant human health risk.Experiments will be conducted to systematically characterize the interactions of gas- and particle-phase organic compounds with indoor dust, including their partitioning and subsequent heterogeneous chemistry. The objectives of this project are to: (1) Characterize the chemical transformation pathways and resulting products from target dust-bound precursors from within complex mixtures of outdoor pollutants (from sources such as motor vehicle, biomass burning, and cooking) that infiltrate the home and become exposed to indoor reactive gases (e.g., ozone, nitrogen oxides, hydroxyl radicals); (2) Identify novel chemical reaction products in lab-generated and genuine complex mixtures of fresh and aged indoor dust using non-targeted mass spectrometry approaches; and (3) Determine the oxidative potential and exposure risks of fresh and aged dust-bound and re-volatilized product mixtures.The chemical composition and exposure risk evaluations of the indoor air studied will be disseminated to the public via an interactive web tool. A series of workshops will be organized for middle school students and their teachers in collaboration with the Institute for School Partnership at Washington University in St. Louis. The project will support students from Lincoln University, a historically Black institution in Jefferson City, MO, to perform laboratory research each summer throughout the project.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

该项目的重点是表征室内空气化学，这是由于有机化合物与机载灰尘的相互作用而产生的。这项工作将提高人们对室内粉尘化学的了解，尤其是在容易受到较高污染物浓度的房屋中，这些污染物浓度来自室内渗透的外部源排放。预计该结果将使对室内空气中的各个化合物或化合物有更好的理解，这些化合物或化合物构成了显着的人类健康风险。将进行实例，以系统地表征与室内粉尘的气体和颗粒相和粒子相的相互作用，包括它们的分配以及随后的异质化学。该项目的目标是：（1）表征化学转化途径和产生的产物，来自目标粉尘结合的前体，来自室外污染物的复杂混合物（来自诸如机动车，生物量燃烧和烹饪），并暴露于房屋并暴露于室内反应性气体（例如，焦点，nItrogoganigy indrodrocy indrocogenys，Hydroxy indro indro indro indro indro indro indro carticy indosigy of）。 （2）使用非靶向的质谱方法，在实验室生成的新鲜和老化室内粉尘的实验室生成和真正的复杂混合物中确定新型化学反应产物； （3）确定新鲜和老化的粉尘结合和重新授粉产品混合物的氧化潜力和暴露风险。所研究的室内空气的化学成分和暴露风险评估将通过交互式网络工具传播给公众。将在与圣路易斯华盛顿大学的学校合作研究所合作，为中学生及其老师举办一系列研讨会。该项目将支持来自密苏里州杰斐逊市历史悠久的黑人机构林肯大学的学生在整个项目中进行实验室研究。该奖项反映了NSF的法定任务，并被认为是值得通过基金会的知识分子的评估来支持的，并具有更广泛的影响。